FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4224211468> ?p ?o ?g. }

• W4224211468 endingPage "3562" @default.
• W4224211468 startingPage "3556" @default.
• W4224211468 abstract "Hydrogen [11C]cyanide ([11C]HCN) is a versatile 11C-labelling agent for the production of 11C-labelled compounds used for positron emission tomography (PET). However, the traditional method for [11C]HCN production requires a dedicated infrastructure, limiting accessibility to [11C]HCN. Herein, we report a simple and efficient [11C]HCN production method that can be easily implemented in 11C production facilities. The immediate production of [11C]HCN was achieved by passing gaseous [11C]methyl iodide ([11C]CH3I) through a small two-layered reaction column. The first layer contained an N-oxide and a sulfoxide for conversion of [11C]CH3I to [11C]formaldehyde ([11C]CH2O). The [11C]CH2O produced was subsequently converted to [11C]HCN in a second layer containing hydroxylamine-O-sulfonic acid. The yield of [11C]HCN produced by the current method was comparable to that of [11C]HCN produced by the traditional method. The use of oxymatrine and diphenyl sulfoxide for [11C]CH2O production prevented deterioration of the molar activity of [11C]HCN. Using this method, compounds labelled with [11C]HCN are now made easily accessible for PET synthesis applications using readily available labware, without the need for the 'traditional' dedicated cyanide synthesis infrastructure." @default.
• W4224211468 created "2022-04-26" @default.
• W4224211468 creator A5038795436 @default.
• W4224211468 creator A5044072322 @default.
• W4224211468 creator A5053346995 @default.
• W4224211468 creator A5066418948 @default.
• W4224211468 creator A5074481547 @default.
• W4224211468 date "2022-01-01" @default.
• W4224211468 modified "2023-10-14" @default.
• W4224211468 title "Rapid ‘on-column’ preparation of hydrogen [¹¹C]cyanide from [¹¹C]methyl iodide <i>via</i> [¹¹C]formaldehyde" @default.
• W4224211468 cites W1480504321 @default.
• W4224211468 cites W1550686208 @default.
• W4224211468 cites W1852665323 @default.
• W4224211468 cites W1921582957 @default.
• W4224211468 cites W1964041012 @default.
• W4224211468 cites W1966272203 @default.
• W4224211468 cites W1967214286 @default.
• W4224211468 cites W1969878437 @default.
• W4224211468 cites W1972989875 @default.
• W4224211468 cites W1975410382 @default.
• W4224211468 cites W1981914102 @default.
• W4224211468 cites W1994689089 @default.
• W4224211468 cites W1995357756 @default.
• W4224211468 cites W2001378503 @default.
• W4224211468 cites W2009016941 @default.
• W4224211468 cites W2016112837 @default.
• W4224211468 cites W2023032810 @default.
• W4224211468 cites W2026132508 @default.
• W4224211468 cites W2027014396 @default.
• W4224211468 cites W2042907121 @default.
• W4224211468 cites W2042944998 @default.
• W4224211468 cites W2054439940 @default.
• W4224211468 cites W2055484187 @default.
• W4224211468 cites W2058760162 @default.
• W4224211468 cites W2060685280 @default.
• W4224211468 cites W2064865731 @default.
• W4224211468 cites W2068729864 @default.
• W4224211468 cites W2071161201 @default.
• W4224211468 cites W2079656529 @default.
• W4224211468 cites W2085547559 @default.
• W4224211468 cites W2086367721 @default.
• W4224211468 cites W2087462044 @default.
• W4224211468 cites W2088945610 @default.
• W4224211468 cites W2094805926 @default.
• W4224211468 cites W2098735745 @default.
• W4224211468 cites W2131770745 @default.
• W4224211468 cites W2135240392 @default.
• W4224211468 cites W2146318041 @default.
• W4224211468 cites W2319489245 @default.
• W4224211468 cites W2320545884 @default.
• W4224211468 cites W2329873351 @default.
• W4224211468 cites W2339380182 @default.
• W4224211468 cites W2410195566 @default.
• W4224211468 cites W2474535754 @default.
• W4224211468 cites W2489083586 @default.
• W4224211468 cites W2520847438 @default.
• W4224211468 cites W2735356684 @default.
• W4224211468 cites W2752969755 @default.
• W4224211468 cites W2762021406 @default.
• W4224211468 cites W2884017587 @default.
• W4224211468 cites W2932784392 @default.
• W4224211468 cites W2996279934 @default.
• W4224211468 cites W3028299631 @default.
• W4224211468 cites W3096729150 @default.
• W4224211468 cites W3190817907 @default.
• W4224211468 cites W3204121968 @default.
• W4224211468 cites W4244558553 @default.
• W4224211468 cites W4253916366 @default.
• W4224211468 doi "https://doi.org/10.1039/d1sc07033a" @default.
• W4224211468 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35432866" @default.
• W4224211468 hasPublicationYear "2022" @default.
• W4224211468 type Work @default.
• W4224211468 citedByCount "3" @default.
• W4224211468 countsByYear W42242114682022 @default.
• W4224211468 countsByYear W42242114682023 @default.
• W4224211468 crossrefType "journal-article" @default.
• W4224211468 hasAuthorship W4224211468A5038795436 @default.
• W4224211468 hasAuthorship W4224211468A5044072322 @default.
• W4224211468 hasAuthorship W4224211468A5053346995 @default.
• W4224211468 hasAuthorship W4224211468A5066418948 @default.
• W4224211468 hasAuthorship W4224211468A5074481547 @default.
• W4224211468 hasBestOaLocation W42242114681 @default.
• W4224211468 hasConcept C134121241 @default.
• W4224211468 hasConcept C178790620 @default.
• W4224211468 hasConcept C185592680 @default.
• W4224211468 hasConcept C191897082 @default.
• W4224211468 hasConcept C192562407 @default.
• W4224211468 hasConcept C2775930285 @default.
• W4224211468 hasConcept C2775999725 @default.
• W4224211468 hasConcept C2778455166 @default.
• W4224211468 hasConcept C2779650833 @default.
• W4224211468 hasConcept C2780073701 @default.
• W4224211468 hasConcept C2781046861 @default.
• W4224211468 hasConcept C512968161 @default.
• W4224211468 hasConceptScore W4224211468C134121241 @default.
• W4224211468 hasConceptScore W4224211468C178790620 @default.
• W4224211468 hasConceptScore W4224211468C185592680 @default.
• W4224211468 hasConceptScore W4224211468C191897082 @default.

• next