Matches in SemOpenAlex for { <https://semopenalex.org/work/W4224212964> ?p ?o ?g. }
Showing items 1 to 84 of
84
with 100 items per page.
- W4224212964 abstract "Abstract Chronic hepatitis B (CHB) infection is a risk factor for hepatocellular carcinoma (HCC). Previous studies showed that elevated levels of Hepatitis B Virus (HBV) DNA and HBsAg are associated with increased HCC risk in patients with chronic HBV infection. Multiple studies showed that high levels of HBV DNA and Hepatitis B Surface Antigen (HBsAg) are associated with higher HCC risk in CHB patients. Patients treated with antiviral therapy may have undetectable or low levels of HBV DNA and HBsAg loss. However, HCC may develop in some patients with low‐level HBV DNA and HBsAg seroconversion. In this study, we evaluated the role of HBcrAg in predicting HBV related HCC development. We searched PubMed, Scopus, and Web of Science databases using keywords (hepatitis B core‐related antigen, hepatocellular carcinoma, liver neoplasm, hepatocellular and hepatic cancer, to identify studies assessing serum level of HBcrAg in patients with CHB and HCC. The search resulted in 184 studies. Seven studies were included: Four of which were retrospective cohort studies, and the rest were prospective cohort, case controls. Six of them reported a higher HBcrAg positivity rate in the HCC group when compared with the HBV DNA assay, yet with similar hazard ratio (HR) in predicting the incidence of HCC. However, four studies found that HBcrAg positivity was an independent risk factor for HCC development with a HR ranging from 3.27 to 7.05. HBV‐related HCC has many proposed biomarkers in its prediction, yet our findings revealed HBcrAg to may have superiority over other biomarkers. High quality studies with bigger sample size research is needed to understand the potential role of HBcrAg in CHB induced HCC." @default.
- W4224212964 created "2022-04-26" @default.
- W4224212964 creator A5001334485 @default.
- W4224212964 creator A5046102455 @default.
- W4224212964 creator A5057632467 @default.
- W4224212964 creator A5066962869 @default.
- W4224212964 creator A5079153438 @default.
- W4224212964 date "2022-04-20" @default.
- W4224212964 modified "2023-09-26" @default.
- W4224212964 title "Hepatitis B virus core‐related antigen (HBcrAg) as a prognostic marker for the development of hepatocellular carcinoma: A mini systematic review of the literature" @default.
- W4224212964 cites W2002144368 @default.
- W4224212964 cites W2004100607 @default.
- W4224212964 cites W2029041074 @default.
- W4224212964 cites W2066303652 @default.
- W4224212964 cites W2104389844 @default.
- W4224212964 cites W2119479641 @default.
- W4224212964 cites W2137652792 @default.
- W4224212964 cites W2159670669 @default.
- W4224212964 cites W2161152775 @default.
- W4224212964 cites W2161348039 @default.
- W4224212964 cites W2167565590 @default.
- W4224212964 cites W2187069076 @default.
- W4224212964 cites W2318766603 @default.
- W4224212964 cites W2528277687 @default.
- W4224212964 cites W2586433173 @default.
- W4224212964 cites W2884027518 @default.
- W4224212964 cites W2896889002 @default.
- W4224212964 cites W2970114132 @default.
- W4224212964 cites W3031914144 @default.
- W4224212964 cites W3035831051 @default.
- W4224212964 cites W3107774535 @default.
- W4224212964 doi "https://doi.org/10.1002/rmv.2353" @default.
- W4224212964 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35441759" @default.
- W4224212964 hasPublicationYear "2022" @default.
- W4224212964 type Work @default.
- W4224212964 citedByCount "2" @default.
- W4224212964 countsByYear W42242129642023 @default.
- W4224212964 crossrefType "journal-article" @default.
- W4224212964 hasAuthorship W4224212964A5001334485 @default.
- W4224212964 hasAuthorship W4224212964A5046102455 @default.
- W4224212964 hasAuthorship W4224212964A5057632467 @default.
- W4224212964 hasAuthorship W4224212964A5066962869 @default.
- W4224212964 hasAuthorship W4224212964A5079153438 @default.
- W4224212964 hasConcept C126322002 @default.
- W4224212964 hasConcept C143998085 @default.
- W4224212964 hasConcept C159047783 @default.
- W4224212964 hasConcept C2522874641 @default.
- W4224212964 hasConcept C2776231280 @default.
- W4224212964 hasConcept C2777382497 @default.
- W4224212964 hasConcept C2777410769 @default.
- W4224212964 hasConcept C2778019345 @default.
- W4224212964 hasConcept C2780593183 @default.
- W4224212964 hasConcept C71924100 @default.
- W4224212964 hasConcept C90924648 @default.
- W4224212964 hasConceptScore W4224212964C126322002 @default.
- W4224212964 hasConceptScore W4224212964C143998085 @default.
- W4224212964 hasConceptScore W4224212964C159047783 @default.
- W4224212964 hasConceptScore W4224212964C2522874641 @default.
- W4224212964 hasConceptScore W4224212964C2776231280 @default.
- W4224212964 hasConceptScore W4224212964C2777382497 @default.
- W4224212964 hasConceptScore W4224212964C2777410769 @default.
- W4224212964 hasConceptScore W4224212964C2778019345 @default.
- W4224212964 hasConceptScore W4224212964C2780593183 @default.
- W4224212964 hasConceptScore W4224212964C71924100 @default.
- W4224212964 hasConceptScore W4224212964C90924648 @default.
- W4224212964 hasIssue "6" @default.
- W4224212964 hasLocation W42242129641 @default.
- W4224212964 hasLocation W42242129642 @default.
- W4224212964 hasOpenAccess W4224212964 @default.
- W4224212964 hasPrimaryLocation W42242129641 @default.
- W4224212964 hasRelatedWork W1493569787 @default.
- W4224212964 hasRelatedWork W2002144368 @default.
- W4224212964 hasRelatedWork W2065538639 @default.
- W4224212964 hasRelatedWork W2089561133 @default.
- W4224212964 hasRelatedWork W2095133085 @default.
- W4224212964 hasRelatedWork W2096808350 @default.
- W4224212964 hasRelatedWork W2124774996 @default.
- W4224212964 hasRelatedWork W2369572641 @default.
- W4224212964 hasRelatedWork W2382250513 @default.
- W4224212964 hasRelatedWork W3030616408 @default.
- W4224212964 hasVolume "32" @default.
- W4224212964 isParatext "false" @default.
- W4224212964 isRetracted "false" @default.
- W4224212964 workType "article" @default.