FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4224215164> ?p ?o ?g. }

• W4224215164 endingPage "75" @default.
• W4224215164 startingPage "65" @default.
• W4224215164 abstract "Abstract Background : Although vast clinical evidence supports the oxidative CVD hypothesis, little is known on the effects of statins on LDL/HDL oxidative functionality. Therefore, the aim of this study was to evaluate the antioxidative effects of rosuvastatin by monitoring the susceptibility of LDL to oxidation and the antioxidative HDL potential in low-to-moderate CV risk subjects. Methods : 40 adult ambulatory patients (aged 53.8±10.9 years, 27 women and 13 men) were included in the study. Data was collected from patients’ records, physical examination, and blood sampling. Subjects were prescribed rosuvastatin at 20mg/day. Traditional risk-factors/indicators, lipid parameters, inflammatory/immune markers, LDL susceptibility to oxidation and HDL antioxidative potential were monitored and statistically analyzed with t-test, Chi-square test, one-way ANOVA, Mann-Whitney, and Kruskal-Wallis tests. Multivariate logistic regression analyses were made. Results were considered significant when p≤0.05. Results : 67% of the patients showed lower susceptibility of LDL to oxidation after rosuvastatin treatment (p=0.03), with no significant effect on baseline LDL oxidation and lag time. All three LDL oxidative indices were seen to be dependent on the subjects’ lipid profile, hemoglobin levels and the IL-1α and IL-8 pro-inflammatory marker levels. 53% of the patients showed higher HDL antioxidative capacity after treatment, but without statistical significance (p=0.07). Increased antioxidative potential of HDL with rosuvastatin treatment was more likely in males (OR=9.350; p=0.010), and subjects achieving lower post-treatment CV relative risk levels (higher CV risk reduction) (OR=0.338; p=0.027). Conclusions : This study suggests the need of a comprehensive approach when investigating oxidative stress and LDL/HDL functions, especially in low-to-moderate CVD risk subjects." @default.
• W4224215164 created "2022-04-26" @default.
• W4224215164 creator A5005123258 @default.
• W4224215164 creator A5005484305 @default.
• W4224215164 creator A5015329406 @default.
• W4224215164 creator A5033280909 @default.
• W4224215164 creator A5041329258 @default.
• W4224215164 creator A5054921818 @default.
• W4224215164 creator A5061191457 @default.
• W4224215164 creator A5089627250 @default.
• W4224215164 date "2022-03-01" @default.
• W4224215164 modified "2023-10-03" @default.
• W4224215164 title "Antioxidative Effects of Rosuvastatin in Low-to-Moderate Cardiovascular Risk Subjects" @default.
• W4224215164 cites W1535628640 @default.
• W4224215164 cites W1597938677 @default.
• W4224215164 cites W1966454858 @default.
• W4224215164 cites W1991523990 @default.
• W4224215164 cites W2036071835 @default.
• W4224215164 cites W2036401451 @default.
• W4224215164 cites W2063169852 @default.
• W4224215164 cites W2109037624 @default.
• W4224215164 cites W2124525963 @default.
• W4224215164 cites W2135503869 @default.
• W4224215164 cites W2140998385 @default.
• W4224215164 cites W2143658317 @default.
• W4224215164 cites W2146992882 @default.
• W4224215164 cites W2212323528 @default.
• W4224215164 cites W2613713616 @default.
• W4224215164 cites W2616074689 @default.
• W4224215164 cites W2619599864 @default.
• W4224215164 cites W2735527928 @default.
• W4224215164 cites W2791992114 @default.
• W4224215164 cites W2889555654 @default.
• W4224215164 cites W2951345394 @default.
• W4224215164 cites W2953536521 @default.
• W4224215164 cites W2978970747 @default.
• W4224215164 cites W3109720983 @default.
• W4224215164 doi "https://doi.org/10.2478/prilozi-2022-0007" @default.
• W4224215164 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35451294" @default.
• W4224215164 hasPublicationYear "2022" @default.
• W4224215164 type Work @default.
• W4224215164 citedByCount "1" @default.
• W4224215164 countsByYear W42242151642023 @default.
• W4224215164 crossrefType "journal-article" @default.
• W4224215164 hasAuthorship W4224215164A5005123258 @default.
• W4224215164 hasAuthorship W4224215164A5005484305 @default.
• W4224215164 hasAuthorship W4224215164A5015329406 @default.
• W4224215164 hasAuthorship W4224215164A5033280909 @default.
• W4224215164 hasAuthorship W4224215164A5041329258 @default.
• W4224215164 hasAuthorship W4224215164A5054921818 @default.
• W4224215164 hasAuthorship W4224215164A5061191457 @default.
• W4224215164 hasAuthorship W4224215164A5089627250 @default.
• W4224215164 hasBestOaLocation W42242151641 @default.
• W4224215164 hasConcept C126322002 @default.
• W4224215164 hasConcept C134018914 @default.
• W4224215164 hasConcept C151956035 @default.
• W4224215164 hasConcept C2778163477 @default.
• W4224215164 hasConcept C2778270857 @default.
• W4224215164 hasConcept C2780499067 @default.
• W4224215164 hasConcept C65409693 @default.
• W4224215164 hasConcept C71924100 @default.
• W4224215164 hasConcept C90924648 @default.
• W4224215164 hasConcept C99476002 @default.
• W4224215164 hasConceptScore W4224215164C126322002 @default.
• W4224215164 hasConceptScore W4224215164C134018914 @default.
• W4224215164 hasConceptScore W4224215164C151956035 @default.
• W4224215164 hasConceptScore W4224215164C2778163477 @default.
• W4224215164 hasConceptScore W4224215164C2778270857 @default.
• W4224215164 hasConceptScore W4224215164C2780499067 @default.
• W4224215164 hasConceptScore W4224215164C65409693 @default.
• W4224215164 hasConceptScore W4224215164C71924100 @default.
• W4224215164 hasConceptScore W4224215164C90924648 @default.
• W4224215164 hasConceptScore W4224215164C99476002 @default.
• W4224215164 hasIssue "1" @default.
• W4224215164 hasLocation W42242151641 @default.
• W4224215164 hasLocation W42242151642 @default.
• W4224215164 hasOpenAccess W4224215164 @default.
• W4224215164 hasPrimaryLocation W42242151641 @default.
• W4224215164 hasRelatedWork W1966504330 @default.
• W4224215164 hasRelatedWork W1979139803 @default.
• W4224215164 hasRelatedWork W2030889776 @default.
• W4224215164 hasRelatedWork W2035331946 @default.
• W4224215164 hasRelatedWork W2037631372 @default.
• W4224215164 hasRelatedWork W2040058909 @default.
• W4224215164 hasRelatedWork W2043355960 @default.
• W4224215164 hasRelatedWork W2132898409 @default.
• W4224215164 hasRelatedWork W2748952813 @default.
• W4224215164 hasRelatedWork W4245035607 @default.
• W4224215164 hasVolume "43" @default.
• W4224215164 isParatext "false" @default.
• W4224215164 isRetracted "false" @default.
• W4224215164 workType "article" @default.