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• W4224230330 abstract "Abstract Objective: This study aimed to assess the efficacy and safety of a new hemostatic gelatin matrix for use in spinal surgery. Methods: From September to December 2020, 54 patients from our hospital were recruited and randomly allocated to a test group or a control group using computer-generated randomization codes. In the test group, the new hemostatic gelatin matrix was used; in the control group, the Surgiflo™ Hemostatic Matrix was used. All operations for both groups were performed by a senior physician, and the following measures were recorded for comparison: (i) rates of successful hemostasis at 5 min; (ii) time to hemostasis; (iii) blood pressure (BP); (iv) red blood (RBC) cell count; and (v) hemoglobin (Hb) levels in the preoperative period, 1 st to 2 nd postoperative days, and 42 nd postoperative day. Adverse events following surgery were also compared. Results: All patients were followed up for at least 6 weeks. In the test group, 24 and 2 cases achieved and did not achieve hemostasis within 5 min, respectively. In the control group, 23 and 2 cases achieved and did not achieve hemostasis within 5 min, respectively. There was no statistical difference between the two groups (P = 0.967). The time to hemostasis, BP, RBC, and Hb in the preoperative period, on the 1 st and 2 nd postoperative days, and 42 nd postoperative day also showed no significant differences between groups (P > 0.05). Conclusion: The new hemostatic gelatin matrix has the same efficacy and safety as that of Surgiflo™ Hemostatic Matrix." @default.
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• W4224230330 date "2022-04-22" @default.
• W4224230330 modified "2023-09-24" @default.
• W4224230330 title "Efficacy and safety analysis of a new hemostatic gelatin matrix for spinal surgery: A randomized controlled study" @default.
• W4224230330 doi "https://doi.org/10.21203/rs.3.rs-1577463/v1" @default.
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