Matches in SemOpenAlex for { <https://semopenalex.org/work/W4224235280> ?p ?o ?g. }
- W4224235280 endingPage "24" @default.
- W4224235280 startingPage "12" @default.
- W4224235280 abstract "Perihilar cholangiocarcinoma (PHC) is defined anatomically as tumors located in the extrahepatic biliary tree proximal to the origin of the cystic duct. However, as the boundary between the extrahepatic and intrahepatic bile ducts is not well defined, PHC potentially includes two types of tumors: one is the extrahepatic type, which arises from the large hilar bile duct, and the other is the intrahepatic type, which has an intrahepatic component with invasion of the hepatic hilus. The new American Joint Commission on Cancer tumor-node-metastasis staging system for PHC was well revised; an important revision is that the Bismuth type IV was removed from T4 stage determinants. Most patients with PHC present with obstructive jaundice, and preoperative biliary drainage is mandatory. Previously, percutaneous transhepatic biliary drainage was used in many centers; however, it has been accepted that endoscopic nasobiliary drainage is the most suitable method for PHC. Recently, inside-stents have also been adopted for biliary drainage, with favorable results. Portal vein embolization is widely performed as presurgical treatment for patients undergoing extended hepatectomy to minimize postoperative liver dysfunction. Surgical resection of PHC is technically demanding and continues to be the most difficult challenge for hepatobiliary surgeons. Because of advances in diagnostic and surgical techniques, surgical outcomes and survival rates after resection have steadily improved. However, survival rates, especially for patients with lymph node metastasis, are unsatisfactory, and establishing a protocol for effective adjuvant chemotherapy is an urgent task. Further synergy of endoscopists, radiologists, oncologists, and surgeons is required to conquer this intractable disease." @default.
- W4224235280 created "2022-04-26" @default.
- W4224235280 creator A5059713499 @default.
- W4224235280 date "2022-03-01" @default.
- W4224235280 modified "2023-09-30" @default.
- W4224235280 title "Perihilar cholangiocarcinoma: A surgeon’s perspective" @default.
- W4224235280 cites W1741750461 @default.
- W4224235280 cites W1965111637 @default.
- W4224235280 cites W1970823825 @default.
- W4224235280 cites W1971456747 @default.
- W4224235280 cites W1973268573 @default.
- W4224235280 cites W1974407986 @default.
- W4224235280 cites W1975895704 @default.
- W4224235280 cites W1977559690 @default.
- W4224235280 cites W1980948970 @default.
- W4224235280 cites W1981125110 @default.
- W4224235280 cites W1982432235 @default.
- W4224235280 cites W1983208778 @default.
- W4224235280 cites W1983402002 @default.
- W4224235280 cites W1989387462 @default.
- W4224235280 cites W1989708996 @default.
- W4224235280 cites W1990729745 @default.
- W4224235280 cites W1992149176 @default.
- W4224235280 cites W1993594108 @default.
- W4224235280 cites W1998917414 @default.
- W4224235280 cites W1999835276 @default.
- W4224235280 cites W2008194516 @default.
- W4224235280 cites W2008242411 @default.
- W4224235280 cites W2008549694 @default.
- W4224235280 cites W2009284687 @default.
- W4224235280 cites W2010862158 @default.
- W4224235280 cites W2011173563 @default.
- W4224235280 cites W2013289012 @default.
- W4224235280 cites W2015787771 @default.
- W4224235280 cites W2028630440 @default.
- W4224235280 cites W2029652643 @default.
- W4224235280 cites W2034770797 @default.
- W4224235280 cites W2035040851 @default.
- W4224235280 cites W2035254040 @default.
- W4224235280 cites W2038265408 @default.
- W4224235280 cites W2039618160 @default.
- W4224235280 cites W2040835705 @default.
- W4224235280 cites W2041210801 @default.
- W4224235280 cites W2041653029 @default.
- W4224235280 cites W2045309761 @default.
- W4224235280 cites W2053274880 @default.
- W4224235280 cites W2054278834 @default.
- W4224235280 cites W2055712625 @default.
- W4224235280 cites W2058183684 @default.
- W4224235280 cites W2061318890 @default.
- W4224235280 cites W2067575315 @default.
- W4224235280 cites W2072953518 @default.
- W4224235280 cites W2073801722 @default.
- W4224235280 cites W2075644682 @default.
- W4224235280 cites W2075957912 @default.
- W4224235280 cites W2077446805 @default.
- W4224235280 cites W2079725382 @default.
- W4224235280 cites W2081150120 @default.
- W4224235280 cites W2086381331 @default.
- W4224235280 cites W2086392787 @default.
- W4224235280 cites W2088140627 @default.
- W4224235280 cites W2089839106 @default.
- W4224235280 cites W2093273760 @default.
- W4224235280 cites W2093325014 @default.
- W4224235280 cites W2094518752 @default.
- W4224235280 cites W2095634270 @default.
- W4224235280 cites W2096998881 @default.
- W4224235280 cites W2104729293 @default.
- W4224235280 cites W2108898444 @default.
- W4224235280 cites W2110284028 @default.
- W4224235280 cites W2112626007 @default.
- W4224235280 cites W2113519579 @default.
- W4224235280 cites W2123524720 @default.
- W4224235280 cites W2130335889 @default.
- W4224235280 cites W2130504424 @default.
- W4224235280 cites W2130947236 @default.
- W4224235280 cites W2134423861 @default.
- W4224235280 cites W2134833177 @default.
- W4224235280 cites W2139489447 @default.
- W4224235280 cites W2140140898 @default.
- W4224235280 cites W2142460968 @default.
- W4224235280 cites W2147796106 @default.
- W4224235280 cites W2148512550 @default.
- W4224235280 cites W2153358651 @default.
- W4224235280 cites W2158114552 @default.
- W4224235280 cites W2166509687 @default.
- W4224235280 cites W2204134524 @default.
- W4224235280 cites W2204289602 @default.
- W4224235280 cites W2258990563 @default.
- W4224235280 cites W2273632183 @default.
- W4224235280 cites W2313652843 @default.
- W4224235280 cites W2315040241 @default.
- W4224235280 cites W2317265960 @default.
- W4224235280 cites W2333767446 @default.
- W4224235280 cites W2415120629 @default.
- W4224235280 cites W2460231246 @default.
- W4224235280 cites W2469789759 @default.
- W4224235280 cites W2518107143 @default.