Matches in SemOpenAlex for { <https://semopenalex.org/work/W4224241473> ?p ?o ?g. }
- W4224241473 abstract "Abstract Among various kinds of fluorine‐substituted biomolecules, 2‐fluoroadenine (2FA) and its derivatives have been actively investigated as therapeutic reagents, radio‐sensitizers, and 19 F NMR probes. In spite of their excellent properties, DNA containing 2FA has not been studied well. For fundamental understanding and future applications to the development of functional nucleic acids, we characterized 2FA‐containing oligonucleotides for canonical right‐handed DNA duplex, G‐quadruplex, and i‐motif structures. Properties of 2FA were similar to native adenine due to the small size of the fluorine atom, but it showed unique features caused by high electronegativity. This work provides useful information for future application of 2FA‐modified DNA." @default.
- W4224241473 created "2022-04-26" @default.
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- W4224241473 date "2022-05-09" @default.
- W4224241473 modified "2023-10-15" @default.
- W4224241473 title "Characterization of 2‐Fluoro‐2’‐deoxyadenosine in Duplex, G‐quadruplex and I‐motif" @default.
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- W4224241473 doi "https://doi.org/10.1002/cbic.202200222" @default.
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