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- W4224253979 endingPage "10317" @default.
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- W4224253979 abstract "Intramolecular interactions are key factors for constructing the secondary conformations of biomolecules and they are also vital for biomolecular functions. Their effect on the surface-enhanced Raman spectroscopy (SERS) spectra is also important for reliable label-free detection. The current work focuses on three GCGC-quadruplexes as model molecules for SERS studies, which contain both the G-quartet and the GCGC-quartet. Their spectra are compared with the ones of the G-quadruplex and the duplex. The present work presents the specific effect of intramolecular interactions, including various Watson-Crick and Hoogsteen hydrogen bonds as well as base stacking, on the SERS signals of closely-related secondary conformations. The overall results indicated a significant influence on the direct label-free detection of DNA molecules and the SERS capability for secondary structural analysis." @default.
- W4224253979 created "2022-04-26" @default.
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- W4224253979 date "2022-01-01" @default.
- W4224253979 modified "2023-09-25" @default.
- W4224253979 title "Revealing the effect of intramolecular interactions on DNA SERS detection: SERS capability for structural analysis" @default.
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- W4224253979 doi "https://doi.org/10.1039/d1cp05607g" @default.
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