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• W4224255062 endingPage "L821" @default.
• W4224255062 startingPage "L804" @default.
• W4224255062 abstract "Although advances in the respiratory management of extremely preterm infants have led to improvements in survival, this progress has not yet extended to a reduction in the incidence of bronchopulmonary dysplasia (BPD). BPD is a complex multifactorial condition that primarily occurs due to disturbances in the regulation of normal pulmonary airspace and vascular development. Preterm birth and exposure to invasive mechanical ventilation also compromises large airway development, leading to significant morbidity and mortality. Although both predisposing and protective genetic and environmental factors have been frequently described in the clinical literature, these findings have had limited impact on the development of effective therapeutic strategies. This gap is likely because the molecular pathways that underlie these observations are yet not fully understood, limiting the ability of researchers to identify novel treatments that can preserve normal lung development and/or enhance cellular repair mechanisms. In this review article, we will outline various well-established clinical observations while identifying key knowledge gaps that need to be filled with carefully designed preclinical experiments. We will address these issues by discussing controversial topics in the pathophysiology, the pathology, and the treatment of BPD, including an evaluation of existing animal models that have been used to answer important questions." @default.
• W4224255062 created "2022-04-26" @default.
• W4224255062 creator A5049642684 @default.
• W4224255062 creator A5062925044 @default.
• W4224255062 date "2022-06-01" @default.
• W4224255062 modified "2023-10-16" @default.
• W4224255062 title "Moving bronchopulmonary dysplasia research from the bedside to the bench" @default.
• W4224255062 cites W1515779841 @default.
• W4224255062 cites W1531021750 @default.
• W4224255062 cites W1543755962 @default.
• W4224255062 cites W1555431179 @default.
• W4224255062 cites W1857797615 @default.
• W4224255062 cites W1936275650 @default.
• W4224255062 cites W1963928796 @default.
• W4224255062 cites W1965007772 @default.
• W4224255062 cites W1968053961 @default.
• W4224255062 cites W1972446219 @default.
• W4224255062 cites W1972695030 @default.
• W4224255062 cites W1974207629 @default.
• W4224255062 cites W1975078682 @default.
• W4224255062 cites W1975525268 @default.
• W4224255062 cites W1975752798 @default.
• W4224255062 cites W1976336434 @default.
• W4224255062 cites W1981360765 @default.
• W4224255062 cites W1986180694 @default.
• W4224255062 cites W1989832114 @default.
• W4224255062 cites W1993734510 @default.
• W4224255062 cites W1994557305 @default.
• W4224255062 cites W1997672418 @default.
• W4224255062 cites W1999194263 @default.
• W4224255062 cites W1999810822 @default.
• W4224255062 cites W2000093553 @default.
• W4224255062 cites W2000433980 @default.
• W4224255062 cites W2001065358 @default.
• W4224255062 cites W2002725229 @default.
• W4224255062 cites W2003679733 @default.
• W4224255062 cites W2004119748 @default.
• W4224255062 cites W2004905707 @default.
• W4224255062 cites W2005719144 @default.
• W4224255062 cites W2006357580 @default.
• W4224255062 cites W2006414860 @default.
• W4224255062 cites W2008983935 @default.
• W4224255062 cites W2009529606 @default.
• W4224255062 cites W2010336370 @default.
• W4224255062 cites W2011266453 @default.
• W4224255062 cites W2012860021 @default.
• W4224255062 cites W2016317398 @default.
• W4224255062 cites W2016465069 @default.
• W4224255062 cites W2016590285 @default.
• W4224255062 cites W2024681203 @default.
• W4224255062 cites W2024962699 @default.
• W4224255062 cites W2025410624 @default.
• W4224255062 cites W2033042544 @default.
• W4224255062 cites W2033829367 @default.
• W4224255062 cites W2040237058 @default.
• W4224255062 cites W2046236004 @default.
• W4224255062 cites W2047714099 @default.
• W4224255062 cites W2049216735 @default.
• W4224255062 cites W2050081577 @default.
• W4224255062 cites W2052191146 @default.
• W4224255062 cites W2052456731 @default.
• W4224255062 cites W2054188002 @default.
• W4224255062 cites W2062194371 @default.
• W4224255062 cites W2063602122 @default.
• W4224255062 cites W2064939222 @default.
• W4224255062 cites W2069894453 @default.
• W4224255062 cites W2073694908 @default.
• W4224255062 cites W2074016895 @default.
• W4224255062 cites W2079115347 @default.
• W4224255062 cites W2079490745 @default.
• W4224255062 cites W2080054123 @default.
• W4224255062 cites W2088749796 @default.
• W4224255062 cites W2089288497 @default.
• W4224255062 cites W2092331833 @default.
• W4224255062 cites W2092784594 @default.
• W4224255062 cites W2092887171 @default.
• W4224255062 cites W2103452292 @default.
• W4224255062 cites W2111593921 @default.
• W4224255062 cites W2113909027 @default.
• W4224255062 cites W2114235313 @default.
• W4224255062 cites W2117073610 @default.
• W4224255062 cites W2119415426 @default.
• W4224255062 cites W2120215146 @default.
• W4224255062 cites W2123163444 @default.
• W4224255062 cites W2123968598 @default.
• W4224255062 cites W2125088463 @default.
• W4224255062 cites W2126081460 @default.
• W4224255062 cites W2131997206 @default.
• W4224255062 cites W2135160692 @default.
• W4224255062 cites W2138666525 @default.
• W4224255062 cites W2138822771 @default.
• W4224255062 cites W2140569066 @default.
• W4224255062 cites W2141885786 @default.
• W4224255062 cites W2151483014 @default.
• W4224255062 cites W2153604360 @default.
• W4224255062 cites W2154498462 @default.
• W4224255062 cites W2154576595 @default.
• W4224255062 cites W2159136750 @default.

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