Matches in SemOpenAlex for { <https://semopenalex.org/work/W4224255710> ?p ?o ?g. }
Showing items 1 to 84 of
84
with 100 items per page.
- W4224255710 endingPage "103" @default.
- W4224255710 startingPage "98" @default.
- W4224255710 abstract "Background Transfusion-dependent thalassemia (TDT) has a major impact on a child’s growth and is associated with stunting, risk of vitamin D deficiency, and decreased insulin-like growth factor-1 (IGF-1). To date, the relationship between vitamin D levels and stunting in TDT remains unclear. Futhermore, the role of vitamin D and IGF-1 in mediating stunting in TDT patients is still unknown. 
 Objective To investigate the relationship between stunting and vitamin D as well as IGF-1 levels in children with TDT.
 Methods This cross-sectional study involved 50 TDT children aged 5 to 18 years, included consecutively from the Pediatric Hemato-oncology Outpatient Clinic, Dr. Soetomo Hospital, Surabaya, East Java. Subjects were divided into two groups: stunted (S) and not stunted (NS). Vitamin D and IGF-1 were evaluated by antibody competitive immunoassay and sandwich-enzyme-linked immunosorbent assay (ELISA), respectively. Age, sex, and duration of repeated transfusion were analyzed as confounding factors.
 Results Median IGF-1 levels were 91.43 (13.67-192.86) ng/mL and 161.53 (17.99-363.01) ng/mL in the S and NS groups, respectively (P=0.011). Mean vitamin D levels were 20 (+ 5.71) ng/mL and 20.46 (5.25) ng/mL in the S and NS groups, respectively (P=0.765). The correlation coefficient (r) of vitamin D and IGF-I levels was not significant. Multivariate analysis showed that low IGF-1 levels, male, and longer duration of repeated transfusions were associated with stunting in children with TDT. 
 Conclusion Low IGF-1 level is associated with stunting in children with TDT. Vitamin D is not significantly associated with either stunting or IGF-1 in children with TDT." @default.
- W4224255710 created "2022-04-26" @default.
- W4224255710 creator A5043447280 @default.
- W4224255710 creator A5048482251 @default.
- W4224255710 creator A5068376019 @default.
- W4224255710 creator A5074026606 @default.
- W4224255710 date "2022-03-07" @default.
- W4224255710 modified "2023-09-27" @default.
- W4224255710 title "Vitamin D, insulin-like growth factor-1, and stunting in children with transfusion-dependent thalassemia" @default.
- W4224255710 cites W1523620087 @default.
- W4224255710 cites W1905352651 @default.
- W4224255710 cites W1988314386 @default.
- W4224255710 cites W2003006151 @default.
- W4224255710 cites W2021094991 @default.
- W4224255710 cites W2044936340 @default.
- W4224255710 cites W2047635292 @default.
- W4224255710 cites W2050722709 @default.
- W4224255710 cites W2057521903 @default.
- W4224255710 cites W2107177713 @default.
- W4224255710 cites W2110863515 @default.
- W4224255710 cites W2149199918 @default.
- W4224255710 cites W2159716292 @default.
- W4224255710 cites W2186181683 @default.
- W4224255710 cites W2577875157 @default.
- W4224255710 cites W2766083547 @default.
- W4224255710 cites W2809146266 @default.
- W4224255710 cites W2894599235 @default.
- W4224255710 cites W3010042905 @default.
- W4224255710 doi "https://doi.org/10.14238/pi62.2.2022.98-103" @default.
- W4224255710 hasPublicationYear "2022" @default.
- W4224255710 type Work @default.
- W4224255710 citedByCount "0" @default.
- W4224255710 crossrefType "journal-article" @default.
- W4224255710 hasAuthorship W4224255710A5043447280 @default.
- W4224255710 hasAuthorship W4224255710A5048482251 @default.
- W4224255710 hasAuthorship W4224255710A5068376019 @default.
- W4224255710 hasAuthorship W4224255710A5074026606 @default.
- W4224255710 hasBestOaLocation W42242557101 @default.
- W4224255710 hasConcept C124490489 @default.
- W4224255710 hasConcept C126322002 @default.
- W4224255710 hasConcept C170493617 @default.
- W4224255710 hasConcept C187212893 @default.
- W4224255710 hasConcept C2775960820 @default.
- W4224255710 hasConcept C2776940978 @default.
- W4224255710 hasConcept C2777799968 @default.
- W4224255710 hasConcept C2779740938 @default.
- W4224255710 hasConcept C2780689927 @default.
- W4224255710 hasConcept C3020110884 @default.
- W4224255710 hasConcept C71924100 @default.
- W4224255710 hasConcept C77350462 @default.
- W4224255710 hasConcept C90924648 @default.
- W4224255710 hasConceptScore W4224255710C124490489 @default.
- W4224255710 hasConceptScore W4224255710C126322002 @default.
- W4224255710 hasConceptScore W4224255710C170493617 @default.
- W4224255710 hasConceptScore W4224255710C187212893 @default.
- W4224255710 hasConceptScore W4224255710C2775960820 @default.
- W4224255710 hasConceptScore W4224255710C2776940978 @default.
- W4224255710 hasConceptScore W4224255710C2777799968 @default.
- W4224255710 hasConceptScore W4224255710C2779740938 @default.
- W4224255710 hasConceptScore W4224255710C2780689927 @default.
- W4224255710 hasConceptScore W4224255710C3020110884 @default.
- W4224255710 hasConceptScore W4224255710C71924100 @default.
- W4224255710 hasConceptScore W4224255710C77350462 @default.
- W4224255710 hasConceptScore W4224255710C90924648 @default.
- W4224255710 hasIssue "2" @default.
- W4224255710 hasLocation W42242557101 @default.
- W4224255710 hasOpenAccess W4224255710 @default.
- W4224255710 hasPrimaryLocation W42242557101 @default.
- W4224255710 hasRelatedWork W1965661929 @default.
- W4224255710 hasRelatedWork W2093952566 @default.
- W4224255710 hasRelatedWork W2130028120 @default.
- W4224255710 hasRelatedWork W2186620321 @default.
- W4224255710 hasRelatedWork W2922359746 @default.
- W4224255710 hasRelatedWork W2937257713 @default.
- W4224255710 hasRelatedWork W3010668005 @default.
- W4224255710 hasRelatedWork W3199428373 @default.
- W4224255710 hasRelatedWork W4229444180 @default.
- W4224255710 hasRelatedWork W4311709114 @default.
- W4224255710 hasVolume "62" @default.
- W4224255710 isParatext "false" @default.
- W4224255710 isRetracted "false" @default.
- W4224255710 workType "article" @default.