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- W4224256373 abstract "Auditory Signal Detection (ASD) theory postulates that auditory verbal hallucinations (AVH) result from an aberrant association of meaningful connection to abstract noises. In this study, schizophrenia (SZ) patients with persistent AVH (N = 17) and matched controls (N = 25) performed an ASD task with concurrent functional near-infrared spectroscopy recording targetting the left dorsolateral prefrontal cortex (L-DLPFC) and left temporoparietal junction (L-TPJ). During the task, discriminability index had a significant negative correlation, and early deoxyhemoglobin (HbR) latency at L-TPJ positively correlated with AVH scores. Also, patients had significantly lower discriminability, early HbR latency at L-TPJ, and delayed latency at L-DLPFC. This finding suggests the presence of ASD abnormalities and impaired auditory processing in SZ patients with AVH supporting ASD-based pathogenesis." @default.
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- W4224256373 date "2022-07-01" @default.
- W4224256373 modified "2023-10-17" @default.
- W4224256373 title "Functional near-infrared spectroscopy in schizophrenia patients with auditory verbal hallucinations: Preliminary observations" @default.
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- W4224256373 doi "https://doi.org/10.1016/j.ajp.2022.103127" @default.
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