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- W4224257067 abstract "Diseases in marine eukaryotic organisms caused by opportunistic pathogens represent a serious threat to our oceans with potential downstream consequences for ecosystem functioning. Disease outbreaks affecting macroalgae are of particular concern due to their critical role as habitat-forming organisms. However, there is limited understanding of the molecular strategies used by macroalgae to respond to opportunistic pathogens. In this study, we used mRNA-sequencing analysis to investigate the early antipathogen response of the model macroalga Delisea pulchra (Rhodophyta) under the environmental conditions that are known to promote the onset of disease. Using de novo assembly methods, 27,586 unique transcripts belonging to D. pulchra were identified that were mostly affiliated with stress response and signal transduction processes. Differential gene expression analysis between a treatment with the known opportunistic pathogen, Aquimarina sp. AD1 (Bacteroidota), and a closely related benign strain (Aquimarina sp. AD10) revealed a downregulation of genes coding for predicted protein metabolism, stress response, energy generation and photosynthesis functions. The rapid repression of genes coding for core cellular processes is likely to interfere with the macroalgal antipathogen response, later leading to infection, tissue damage and bleaching symptoms. Overall, this study provides valuable insight into the genetic features of D. pulchra, highlighting potential antipathogen response mechanisms of macroalgae and contributing to an improved understanding of host-pathogen interactions in a changing environment." @default.
- W4224257067 created "2022-04-26" @default.
- W4224257067 creator A5024764606 @default.
- W4224257067 creator A5025444019 @default.
- W4224257067 creator A5026607741 @default.
- W4224257067 creator A5032188457 @default.
- W4224257067 date "2022-05-04" @default.
- W4224257067 modified "2023-10-14" @default.
- W4224257067 title "Pathogen exposure leads to a transcriptional downregulation of core cellular functions that may dampen the immune response in a macroalga" @default.
- W4224257067 cites W1483272085 @default.
- W4224257067 cites W1831103454 @default.
- W4224257067 cites W1853184557 @default.
- W4224257067 cites W1865938512 @default.
- W4224257067 cites W1893532359 @default.
- W4224257067 cites W1901798979 @default.
- W4224257067 cites W1905657580 @default.
- W4224257067 cites W1968816051 @default.
- W4224257067 cites W1975331444 @default.
- W4224257067 cites W1984947863 @default.
- W4224257067 cites W1989546697 @default.
- W4224257067 cites W1989886263 @default.
- W4224257067 cites W1994369174 @default.
- W4224257067 cites W1995979535 @default.
- W4224257067 cites W2002821316 @default.
- W4224257067 cites W2005009733 @default.
- W4224257067 cites W2011874398 @default.
- W4224257067 cites W2015951063 @default.
- W4224257067 cites W2026262911 @default.
- W4224257067 cites W2029149923 @default.
- W4224257067 cites W2030884812 @default.
- W4224257067 cites W2033604071 @default.
- W4224257067 cites W2039521726 @default.
- W4224257067 cites W2041119476 @default.
- W4224257067 cites W2049221635 @default.
- W4224257067 cites W2053384550 @default.
- W4224257067 cites W2063820323 @default.
- W4224257067 cites W2066804688 @default.
- W4224257067 cites W2072654764 @default.
- W4224257067 cites W2072913884 @default.
- W4224257067 cites W2073585538 @default.
- W4224257067 cites W2075768482 @default.
- W4224257067 cites W2091091274 @default.
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- W4224257067 cites W2100833438 @default.
- W4224257067 cites W2102103362 @default.
- W4224257067 cites W2103539617 @default.
- W4224257067 cites W2114104545 @default.
- W4224257067 cites W2120454847 @default.
- W4224257067 cites W2125111246 @default.
- W4224257067 cites W2126419817 @default.
- W4224257067 cites W2132616061 @default.
- W4224257067 cites W2137019479 @default.
- W4224257067 cites W2139569318 @default.
- W4224257067 cites W2145633515 @default.
- W4224257067 cites W2151380059 @default.
- W4224257067 cites W2153950899 @default.
- W4224257067 cites W2156125289 @default.
- W4224257067 cites W2158125657 @default.
- W4224257067 cites W2161586263 @default.
- W4224257067 cites W2164154943 @default.
- W4224257067 cites W2168342464 @default.
- W4224257067 cites W2170747616 @default.
- W4224257067 cites W2171091522 @default.
- W4224257067 cites W2171601148 @default.
- W4224257067 cites W2178043251 @default.
- W4224257067 cites W2468532002 @default.
- W4224257067 cites W2470740215 @default.
- W4224257067 cites W2592811885 @default.
- W4224257067 cites W2606354091 @default.
- W4224257067 cites W2769999772 @default.
- W4224257067 cites W2773765818 @default.
- W4224257067 cites W2775647432 @default.
- W4224257067 cites W2788121537 @default.
- W4224257067 cites W2802959259 @default.
- W4224257067 cites W2803787045 @default.
- W4224257067 cites W2805918882 @default.
- W4224257067 cites W2901181752 @default.
- W4224257067 cites W2902256103 @default.
- W4224257067 cites W2912990441 @default.
- W4224257067 cites W2921173984 @default.
- W4224257067 cites W2924921298 @default.
- W4224257067 cites W2937720241 @default.
- W4224257067 cites W2941072767 @default.
- W4224257067 cites W2971073877 @default.
- W4224257067 cites W2979888523 @default.
- W4224257067 cites W2979981170 @default.
- W4224257067 cites W2989775567 @default.
- W4224257067 cites W3094776514 @default.
- W4224257067 cites W3188880897 @default.
- W4224257067 cites W3208311864 @default.
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- W4224257067 doi "https://doi.org/10.1111/mec.16476" @default.
- W4224257067 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35445473" @default.
- W4224257067 hasPublicationYear "2022" @default.
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