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• W4224306554 endingPage "109086" @default.
• W4224306554 startingPage "109086" @default.
• W4224306554 abstract "We had previously found that chicken eyes with normal visual experience grow larger when they have more L cones, relative to M cones. It is not known whether also S cone abundancies may affect eye size, whether cone abundancy ratios can also affect the amount of deprivation myopia that is induced by diffusers in front of the eyes, and whether broadband white light with added energy in the blue may reduce the development of deprivation myopia. Therefore, chickens were monocularly treated with diffusers and raised under three different light conditions with increasing amounts of energy in the blue but with matched total illuminance. L, M and S cones were counted in fresh retinal tissues after the experiments. It was found that adding energy in the blue did not significantly inhibit deprivation myopia, nor did it make uncovered eyes more hyperopic. However, more S cones, relative to L cones, were correlated with more hyperopic refractions in eyes with normal vision. M to L, L to S and M to S cone ratios were also correlated with the amount of induced deprivation myopia. Interestingly, in deprivation myopia, the correlations between cone abundancy ratios with refractive states had reverted signs: eyes with more S cones developed more myopia. Since cone abundancy ratios remained correlated in both eyes, no matter whether eyes had normal vision, were deprived or were exposed to different light spectra, they appear genetically determined. We conclude that, among other factors, inherited cone abundancy ratios determine both normal refractive development and deprivation myopia in the chicken while adding more blue light to a broadband light spectrum had no effect." @default.
• W4224306554 created "2022-04-26" @default.
• W4224306554 creator A5031262025 @default.
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• W4224306554 date "2022-06-01" @default.
• W4224306554 modified "2023-10-14" @default.
• W4224306554 title "Impact of cone abundancy ratios and light spectra on emmetropization in chickens" @default.
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• W4224306554 doi "https://doi.org/10.1016/j.exer.2022.109086" @default.
• W4224306554 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35469896" @default.
• W4224306554 hasPublicationYear "2022" @default.
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