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- W4224313622 abstract "Early Parkinson’s disease (PD) may cause respiratory dysfunction; however the findings vary among studies. The aim of the preliminary prospective observational study was to explore the deterioration of pulmonary function at various stages in patients with early PD. A total of 237 patients with PD were screened. Fifty-six patients were included (modified Hoehn and Yahr stage ≤ 2.5). In addition, 56 age-matched healthy controls were also included in the study. Significant differences between the PD and control groups were found in all the investigated lung-function parameters. The maximal voluntary ventilation (MVV) percent predicted was the only parameter that distinguished PD stages (101.1 ± 14.9% vs. 82.8 ± 19.2% vs. 71.4 ± 12.9%, Hoehn and Yahr stages 1.5 vs. 2 vs. 2.5, respectively; p < 0.005). MVV could be the most sensitive parameter for distinguishing the severity of early-stage PD." @default.
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- W4224313622 date "2022-04-25" @default.
- W4224313622 modified "2023-09-26" @default.
- W4224313622 title "Abnormal Pulmonary Function in Early Parkinson’s Disease: A Preliminary Prospective Observational Study" @default.
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- W4224313622 doi "https://doi.org/10.1007/s00408-022-00533-2" @default.
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