Matches in SemOpenAlex for { <https://semopenalex.org/work/W4224313838> ?p ?o ?g. }
- W4224313838 endingPage "15230" @default.
- W4224313838 startingPage "15223" @default.
- W4224313838 abstract "Breast cancer appears to be one of the leading causes of cancer-related morbidity and mortality for women worldwide. The accurate and rapid diagnosis of breast cancer is hence critical for the treatment and prognosis of patients. With the vibrational fingerprint information and high detection sensitivity, surface-enhanced Raman spectroscopy (SERS) has been extensively applied in biomedicine. Here, an optimized bimetallic nanosphere (Au@Ag NS) 3D substrate was fabricated for the aim of the diagnosis of breast cancer based on the SERS analysis of the extracellular metabolites. The unique stacking mode of 3D Au@Ag NSs provided multiple plasmonic hot spots according to the theoretical calculations of the electromagnetic field distribution. The low relative standard deviation (RSD = 2.7%) and high enhancement factor (EF = 1.42 × 105) proved the uniformity and high sensitivity. More importantly, the normal breast cells and breast cancer cells could be readily distinguished from the corresponding SERS spectra based on the extracellular metabolites. Furthermore, the clear clusters of SERS spectra from MCF-7 and MDA-MB-231 extracellular metabolites in the orthogonal partial least-squares discriminant analysis plot indicate the distinct metabolic fingerprint between breast cancer cells, which imply their potential clinical application in the diagnosis of breast cancer." @default.
- W4224313838 created "2022-04-26" @default.
- W4224313838 creator A5010283662 @default.
- W4224313838 creator A5025746827 @default.
- W4224313838 creator A5026047112 @default.
- W4224313838 creator A5027067615 @default.
- W4224313838 creator A5049688400 @default.
- W4224313838 creator A5081285185 @default.
- W4224313838 date "2022-04-24" @default.
- W4224313838 modified "2023-10-15" @default.
- W4224313838 title "High Uniformity and Enhancement Au@AgNS 3D Substrates for the Diagnosis of Breast Cancer" @default.
- W4224313838 cites W1757407923 @default.
- W4224313838 cites W1976737565 @default.
- W4224313838 cites W1992450009 @default.
- W4224313838 cites W2036374319 @default.
- W4224313838 cites W2042929094 @default.
- W4224313838 cites W2046808714 @default.
- W4224313838 cites W2077055938 @default.
- W4224313838 cites W2109909368 @default.
- W4224313838 cites W2150198834 @default.
- W4224313838 cites W2255892726 @default.
- W4224313838 cites W2314211840 @default.
- W4224313838 cites W2316180345 @default.
- W4224313838 cites W2345654890 @default.
- W4224313838 cites W2517468343 @default.
- W4224313838 cites W2615498501 @default.
- W4224313838 cites W2760537261 @default.
- W4224313838 cites W2770242618 @default.
- W4224313838 cites W2774281740 @default.
- W4224313838 cites W2791592432 @default.
- W4224313838 cites W2797445881 @default.
- W4224313838 cites W2800838988 @default.
- W4224313838 cites W2804279294 @default.
- W4224313838 cites W2904703066 @default.
- W4224313838 cites W2941413126 @default.
- W4224313838 cites W2947085612 @default.
- W4224313838 cites W2948528372 @default.
- W4224313838 cites W2964656561 @default.
- W4224313838 cites W2969387066 @default.
- W4224313838 cites W2970641546 @default.
- W4224313838 cites W2981547805 @default.
- W4224313838 cites W2982346646 @default.
- W4224313838 cites W3015202523 @default.
- W4224313838 cites W3022456269 @default.
- W4224313838 cites W3037174894 @default.
- W4224313838 cites W3096116629 @default.
- W4224313838 cites W3113187892 @default.
- W4224313838 cites W3128381485 @default.
- W4224313838 cites W3145635272 @default.
- W4224313838 cites W3162543922 @default.
- W4224313838 cites W4205724345 @default.
- W4224313838 doi "https://doi.org/10.1021/acsomega.2c01453" @default.
- W4224313838 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35572747" @default.
- W4224313838 hasPublicationYear "2022" @default.
- W4224313838 type Work @default.
- W4224313838 citedByCount "2" @default.
- W4224313838 countsByYear W42243138382023 @default.
- W4224313838 crossrefType "journal-article" @default.
- W4224313838 hasAuthorship W4224313838A5010283662 @default.
- W4224313838 hasAuthorship W4224313838A5025746827 @default.
- W4224313838 hasAuthorship W4224313838A5026047112 @default.
- W4224313838 hasAuthorship W4224313838A5027067615 @default.
- W4224313838 hasAuthorship W4224313838A5049688400 @default.
- W4224313838 hasAuthorship W4224313838A5081285185 @default.
- W4224313838 hasBestOaLocation W42243138381 @default.
- W4224313838 hasConcept C120665830 @default.
- W4224313838 hasConcept C121332964 @default.
- W4224313838 hasConcept C121608353 @default.
- W4224313838 hasConcept C126322002 @default.
- W4224313838 hasConcept C169573571 @default.
- W4224313838 hasConcept C18903297 @default.
- W4224313838 hasConcept C191897082 @default.
- W4224313838 hasConcept C192562407 @default.
- W4224313838 hasConcept C2777289219 @default.
- W4224313838 hasConcept C2777790068 @default.
- W4224313838 hasConcept C33347731 @default.
- W4224313838 hasConcept C40003534 @default.
- W4224313838 hasConcept C43411465 @default.
- W4224313838 hasConcept C46141821 @default.
- W4224313838 hasConcept C530470458 @default.
- W4224313838 hasConcept C544153396 @default.
- W4224313838 hasConcept C71924100 @default.
- W4224313838 hasConcept C86803240 @default.
- W4224313838 hasConceptScore W4224313838C120665830 @default.
- W4224313838 hasConceptScore W4224313838C121332964 @default.
- W4224313838 hasConceptScore W4224313838C121608353 @default.
- W4224313838 hasConceptScore W4224313838C126322002 @default.
- W4224313838 hasConceptScore W4224313838C169573571 @default.
- W4224313838 hasConceptScore W4224313838C18903297 @default.
- W4224313838 hasConceptScore W4224313838C191897082 @default.
- W4224313838 hasConceptScore W4224313838C192562407 @default.
- W4224313838 hasConceptScore W4224313838C2777289219 @default.
- W4224313838 hasConceptScore W4224313838C2777790068 @default.
- W4224313838 hasConceptScore W4224313838C33347731 @default.
- W4224313838 hasConceptScore W4224313838C40003534 @default.
- W4224313838 hasConceptScore W4224313838C43411465 @default.
- W4224313838 hasConceptScore W4224313838C46141821 @default.
- W4224313838 hasConceptScore W4224313838C530470458 @default.