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• W4224314574 startingPage "379" @default.
• W4224314574 abstract "Plants perceive pathogenic threats from the environment that have evaded preformed barriers through pattern recognition receptors (PRRs) that recognise microbe-associated molecular patterns (MAMPs). The perception of and triggered defence to lipopolysaccharides (LPSs) as a MAMP is well-studied in mammals, but little is known in plants, including the PRR(s). Understanding LPS-induced secondary metabolites and perturbed metabolic pathways in Arabidopsis will be key to generating disease-resistant plants and improving global plant crop yield. Recently, Arabidopsis LPS-binding protein (LBP) and bactericidal/permeability-increasing protein (BPI)-related proteins (LBP/BPI related-1) and (LBP/BPI related-2) were shown to perceive LPS from Pseudomonas aeruginosa and trigger defence responses. In turn, brassinosteroid insensitive 1 (BRI1)-associated receptor kinase 1 (BAK1) is a well-established co-receptor for several defence-related PRRs in plants. Due to the lack of knowledge pertaining to LPS perception in plants and given the involvement of the afore-mentioned proteins in MAMPs recognition, in this study, Arabidopsis wild type (WT) and mutant (lbr2-2 and bak1-4) plants were pressure-infiltrated with LPSs purified from Pseudomonas syringae pv. tomato DC3000 (Pst) and Xanthomonas campestris pv. campestris 8004 (Xcc). Metabolites were extracted from the leaves at four time points over a 24 h period and analysed by UHPLC-MS, generating distinct metabolite profiles. Data analysed using unsupervised and supervised multivariate data analysis (MVDA) tools generated results that reflected time- and treatment-related variations after both LPS chemotypes treatments. Forty-five significant metabolites were putatively annotated and belong to the following groups: glucosinolates, hydroxycinnamic acid derivatives, flavonoids, lignans, lipids, oxylipins, arabidopsides and phytohormones, while metabolic pathway analysis (MetPA) showed enrichment of flavone and flavanol biosynthesis, phenylpropanoid biosynthesis, alpha-linolenic acid metabolism and glucosinolate biosynthesis. Distinct metabolite accumulations depended on the LPS chemotype and the genetic background of the lbr2-2 and bak1-4 mutants. This study highlights the role of LPSs in the reprogramming Arabidopsis metabolism into a defensive state, and the possible role of LBR and BAK1 proteins in LPSs perception and thus plant defence against pathogenic bacteria." @default.
• W4224314574 created "2022-04-26" @default.
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• W4224314574 date "2022-04-22" @default.
• W4224314574 modified "2023-09-25" @default.
• W4224314574 title "Untargeted Metabolomics Profiling of Arabidopsis WT, lbr-2-2 and bak1-4 Mutants Following Treatment with Two LPS Chemotypes" @default.
• W4224314574 cites W1611854178 @default.
• W4224314574 cites W1810468221 @default.
• W4224314574 cites W1905904564 @default.
• W4224314574 cites W1967737318 @default.
• W4224314574 cites W1970342847 @default.
• W4224314574 cites W1977087029 @default.
• W4224314574 cites W1987003587 @default.
• W4224314574 cites W1987582069 @default.
• W4224314574 cites W1994223088 @default.
• W4224314574 cites W1994602890 @default.
• W4224314574 cites W1996611722 @default.
• W4224314574 cites W1997062226 @default.
• W4224314574 cites W1997878447 @default.
• W4224314574 cites W2006638034 @default.
• W4224314574 cites W2015134345 @default.
• W4224314574 cites W2017073911 @default.
• W4224314574 cites W2017485306 @default.
• W4224314574 cites W2020245878 @default.
• W4224314574 cites W2023650844 @default.
• W4224314574 cites W2025635901 @default.
• W4224314574 cites W2038606732 @default.
• W4224314574 cites W2045369223 @default.
• W4224314574 cites W2046790027 @default.
• W4224314574 cites W2054317956 @default.
• W4224314574 cites W2065679561 @default.
• W4224314574 cites W2071745577 @default.
• W4224314574 cites W2079273380 @default.
• W4224314574 cites W2083813609 @default.
• W4224314574 cites W2087900386 @default.
• W4224314574 cites W2091080924 @default.
• W4224314574 cites W2091956761 @default.
• W4224314574 cites W2092605841 @default.
• W4224314574 cites W2099130699 @default.
• W4224314574 cites W2106951893 @default.
• W4224314574 cites W2109770073 @default.
• W4224314574 cites W2110229779 @default.
• W4224314574 cites W2121500212 @default.
• W4224314574 cites W2122221811 @default.
• W4224314574 cites W2124911115 @default.
• W4224314574 cites W2125979970 @default.
• W4224314574 cites W2129963309 @default.
• W4224314574 cites W2132066552 @default.
• W4224314574 cites W2147270084 @default.
• W4224314574 cites W2148680876 @default.
• W4224314574 cites W2149756786 @default.
• W4224314574 cites W2160607514 @default.
• W4224314574 cites W2161053859 @default.
• W4224314574 cites W2165405896 @default.
• W4224314574 cites W2169005195 @default.
• W4224314574 cites W2170723243 @default.
• W4224314574 cites W2177012362 @default.
• W4224314574 cites W2280547557 @default.
• W4224314574 cites W2298511681 @default.
• W4224314574 cites W2413979805 @default.
• W4224314574 cites W2416771819 @default.
• W4224314574 cites W2419132153 @default.
• W4224314574 cites W2522702698 @default.
• W4224314574 cites W2606991946 @default.
• W4224314574 cites W2619148567 @default.
• W4224314574 cites W2764064372 @default.
• W4224314574 cites W2779666144 @default.
• W4224314574 cites W2867153182 @default.
• W4224314574 cites W2909313627 @default.
• W4224314574 cites W2936955405 @default.
• W4224314574 cites W2938269089 @default.
• W4224314574 cites W2942776357 @default.
• W4224314574 cites W2976562089 @default.
• W4224314574 cites W2989939095 @default.
• W4224314574 cites W2995167752 @default.
• W4224314574 cites W3000121253 @default.
• W4224314574 cites W3023728839 @default.
• W4224314574 cites W3088210540 @default.
• W4224314574 cites W3088470157 @default.
• W4224314574 cites W3127410500 @default.
• W4224314574 cites W3159995035 @default.
• W4224314574 cites W3162639002 @default.
• W4224314574 cites W3164329025 @default.
• W4224314574 cites W4206340987 @default.
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• W4224314574 doi "https://doi.org/10.3390/metabo12050379" @default.
• W4224314574 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35629883" @default.
• W4224314574 hasPublicationYear "2022" @default.
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