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- W4224320770 endingPage "696" @default.
- W4224320770 startingPage "684" @default.
- W4224320770 abstract "Abstract Across mammalian species, it has been demonstrated that sex influences birth weight, with males being heavier than females; a characteristic that can be observed from early gestation. Male piglets are more likely to be stillborn and have greater preweaning mortality than their female littermates, despite the additional maternal investment into male fetal growth. Given the conserved nature of the genome between the sexes, it is hypothesized that these developmental differences between males and females are most likely orchestrated by differential placental adaptation. This review summarizes the current understanding of fetal sex‐specific differences in placental and endometrial structure and function, with an emphasis on pathways found to be differentially regulated in the pig including angiogenesis, apoptosis, and proliferation. Given the importance of piglet sex in agricultural enterprises, and the potential for skewed litter sex ratios, it is imperative to improve understanding of the relationship between fetal sex and molecular signaling in both the placenta and endometria across gestation." @default.
- W4224320770 created "2022-04-26" @default.
- W4224320770 creator A5008008924 @default.
- W4224320770 creator A5053867963 @default.
- W4224320770 creator A5089670220 @default.
- W4224320770 date "2022-04-25" @default.
- W4224320770 modified "2023-10-14" @default.
- W4224320770 title "Sexual dimorphism in placental development and function: Comparative physiology with an emphasis on the pig" @default.
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- W4224320770 doi "https://doi.org/10.1002/mrd.23573" @default.
- W4224320770 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35466463" @default.
- W4224320770 hasPublicationYear "2022" @default.
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