FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4224488462> ?p ?o ?g. }

• W4224488462 endingPage "778" @default.
• W4224488462 startingPage "768" @default.
• W4224488462 abstract "The predicted repertoire of type III secretion system effectors (T3SEs) in Erwinia tracheiphila, causal agent of cucurbit bacterial wilt, is much larger than in xylem pathogens in the closely related genera Erwinia and Pantoea. The genomes of strains BHKY and SCR3, which represent distinct E. tracheiphila clades, encode at least 6 clade-specific and 12 shared T3SEs. The strains expressed the majority of the T3SE genes examined in planta. Among the shared T3SE genes, eop1 was expressed most highly in both strains in squash ( Cucurbita pepo) and muskmelon ( Cucumis melo) but the clade-specific gene avrRpm2 was expressed 40- to 900-fold more than eop1 in BHKY. The T3SEs AvrRpm2, Eop1, SrfC, and DspE contributed to BHKY virulence on squash and muskmelon, as shown using combinatorial mutants involving six T3SEs, whereas OspG and AvrB4 contributed to BHKY virulence only on muskmelon, demonstrating host-specific virulence functions. Moreover, Eop1 was functionally redundant with AvrRpm2, SrfC, OspG, and AvrB4 in BHKY, and BHKY mutants lacking up to five effector genes showed similar virulence to mutants lacking only two genes. The T3SEs OspG, AvrB4, and DspE contributed additively to SCR3 virulence on muskmelon and were not functionally redundant with Eop1. Rather, loss of eop1 and avrB4 restored wild-type virulence to the avrB4 mutant, suggesting that Eop1 suppresses a functionally redundant effector in SCR3. These results highlight functional differences in effector inventories between two E. tracheiphila clades, provide the first evidence of OspG as a phytopathogen effector, and suggest that Eop1 may be a metaeffector influencing virulence. [Formula: see text] Copyright © 2022 The Author(s). This is an open access article distributed under the CC BY 4.0 International license ." @default.
• W4224488462 created "2022-04-27" @default.
• W4224488462 creator A5005829756 @default.
• W4224488462 creator A5006080854 @default.
• W4224488462 creator A5081541319 @default.
• W4224488462 date "2022-09-01" @default.
• W4224488462 modified "2023-09-25" @default.
• W4224488462 title "Expression and Functional Analysis of the Type III Secretion System Effector Repertoire of the Xylem Pathogen <i>Erwinia tracheiphila</i> on Cucurbits" @default.
• W4224488462 cites W1492437640 @default.
• W4224488462 cites W1936138641 @default.
• W4224488462 cites W1977157440 @default.
• W4224488462 cites W1982459012 @default.
• W4224488462 cites W2004548026 @default.
• W4224488462 cites W2013288118 @default.
• W4224488462 cites W2018714810 @default.
• W4224488462 cites W2072895708 @default.
• W4224488462 cites W2081211654 @default.
• W4224488462 cites W2084879868 @default.
• W4224488462 cites W2096647798 @default.
• W4224488462 cites W2105061333 @default.
• W4224488462 cites W2113778418 @default.
• W4224488462 cites W2114453090 @default.
• W4224488462 cites W2124081239 @default.
• W4224488462 cites W2124469007 @default.
• W4224488462 cites W2126981014 @default.
• W4224488462 cites W2132696757 @default.
• W4224488462 cites W2138625184 @default.
• W4224488462 cites W2139142419 @default.
• W4224488462 cites W2142298292 @default.
• W4224488462 cites W2149516300 @default.
• W4224488462 cites W2157979157 @default.
• W4224488462 cites W2170488656 @default.
• W4224488462 cites W2171673901 @default.
• W4224488462 cites W2172070570 @default.
• W4224488462 cites W2291003270 @default.
• W4224488462 cites W2346398016 @default.
• W4224488462 cites W2470764317 @default.
• W4224488462 cites W2508804886 @default.
• W4224488462 cites W2545827800 @default.
• W4224488462 cites W2551837899 @default.
• W4224488462 cites W2559133556 @default.
• W4224488462 cites W2562690213 @default.
• W4224488462 cites W2792833919 @default.
• W4224488462 cites W2804210907 @default.
• W4224488462 cites W2906225254 @default.
• W4224488462 cites W2942138420 @default.
• W4224488462 cites W2952542037 @default.
• W4224488462 cites W2954264549 @default.
• W4224488462 cites W2954682214 @default.
• W4224488462 cites W2990100334 @default.
• W4224488462 cites W3048663396 @default.
• W4224488462 cites W3119117373 @default.
• W4224488462 cites W3122762908 @default.
• W4224488462 cites W3134402674 @default.
• W4224488462 cites W3160710237 @default.
• W4224488462 cites W3165040380 @default.
• W4224488462 cites W3200914509 @default.
• W4224488462 cites W4225278421 @default.
• W4224488462 cites W4226128034 @default.
• W4224488462 cites W4233809519 @default.
• W4224488462 doi "https://doi.org/10.1094/mpmi-01-22-0002-r" @default.
• W4224488462 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35471035" @default.
• W4224488462 hasPublicationYear "2022" @default.
• W4224488462 type Work @default.
• W4224488462 citedByCount "1" @default.
• W4224488462 countsByYear W42244884622022 @default.
• W4224488462 crossrefType "journal-article" @default.
• W4224488462 hasAuthorship W4224488462A5005829756 @default.
• W4224488462 hasAuthorship W4224488462A5006080854 @default.
• W4224488462 hasAuthorship W4224488462A5081541319 @default.
• W4224488462 hasBestOaLocation W42244884621 @default.
• W4224488462 hasConcept C104317684 @default.
• W4224488462 hasConcept C130211564 @default.
• W4224488462 hasConcept C143065580 @default.
• W4224488462 hasConcept C172854840 @default.
• W4224488462 hasConcept C181199279 @default.
• W4224488462 hasConcept C2776681119 @default.
• W4224488462 hasConcept C2778369795 @default.
• W4224488462 hasConcept C2778495000 @default.
• W4224488462 hasConcept C2780746887 @default.
• W4224488462 hasConcept C51785407 @default.
• W4224488462 hasConcept C54355233 @default.
• W4224488462 hasConcept C55493867 @default.
• W4224488462 hasConcept C59822182 @default.
• W4224488462 hasConcept C60987743 @default.
• W4224488462 hasConcept C86803240 @default.
• W4224488462 hasConcept C89423630 @default.
• W4224488462 hasConcept C95444343 @default.
• W4224488462 hasConceptScore W4224488462C104317684 @default.
• W4224488462 hasConceptScore W4224488462C130211564 @default.
• W4224488462 hasConceptScore W4224488462C143065580 @default.
• W4224488462 hasConceptScore W4224488462C172854840 @default.
• W4224488462 hasConceptScore W4224488462C181199279 @default.
• W4224488462 hasConceptScore W4224488462C2776681119 @default.
• W4224488462 hasConceptScore W4224488462C2778369795 @default.
• W4224488462 hasConceptScore W4224488462C2778495000 @default.
• W4224488462 hasConceptScore W4224488462C2780746887 @default.
• W4224488462 hasConceptScore W4224488462C51785407 @default.

• next