Matches in SemOpenAlex for { <https://semopenalex.org/work/W4224509129> ?p ?o ?g. }
- W4224509129 endingPage "109473" @default.
- W4224509129 startingPage "109473" @default.
- W4224509129 abstract "Studies examining the impact of pharmacy-dispensed naloxone programs on fatal opioid overdose rates are lacking. We examined the impact of the publicly funded Ontario Naloxone Program for Pharmacies (ONPP), implemented in June 2016, on provincial rates of opioid overdose deaths. We conducted a population-based interrupted time-series study between July 1, 2012 and December 31, 2018. We considered a parsimonious model with terms for time, ONPP implementation, and time following the ONPP implementation. Models were adjusted for population characteristics, number of pharmacies and rate of naloxone distributed through non-pharmacy sites within provincial public health units. In the parsimonious model, the ONPP was associated with a non-significant 9% reduction in the level of fatal opioid overdoses (rate ratio [RR] 0.91; 95% confidence interval [CI] 0.79–1.06), a finding that was most pronounced in regions in the lowest tertile of implementation (RR 0.75; 95% CI 0.62–0.91). Following multivariable adjustment, there was an increase in the level (RR 1.06; 95% CI 0.94–1.19) and slope change (RR 1.06; 95% CI 1.02–1.10) of fatal overdose rates. The ONPP is insufficient as a single intervention to meaningfully reduce rates of fatal opioid overdoses during a period in which the cause of these deaths shifted from prescription opioids to highly potent fentanyl analogs. Access to additional harm reduction, treatment, and other interventions is necessary to prevent deaths and optimize the health of people who use drugs." @default.
- W4224509129 created "2022-04-27" @default.
- W4224509129 creator A5014847345 @default.
- W4224509129 creator A5026094776 @default.
- W4224509129 creator A5036298172 @default.
- W4224509129 creator A5053276850 @default.
- W4224509129 creator A5054833763 @default.
- W4224509129 creator A5086006866 @default.
- W4224509129 date "2022-07-01" @default.
- W4224509129 modified "2023-10-18" @default.
- W4224509129 title "Impact of a publicly funded pharmacy-dispensed naloxone program on fatal opioid overdose rates: A population-based study" @default.
- W4224509129 cites W1648774293 @default.
- W4224509129 cites W1856114993 @default.
- W4224509129 cites W1976566530 @default.
- W4224509129 cites W2031323283 @default.
- W4224509129 cites W2065531940 @default.
- W4224509129 cites W2068322846 @default.
- W4224509129 cites W2101831741 @default.
- W4224509129 cites W2139852527 @default.
- W4224509129 cites W2142180129 @default.
- W4224509129 cites W2165702384 @default.
- W4224509129 cites W2191045458 @default.
- W4224509129 cites W2283934245 @default.
- W4224509129 cites W2331803526 @default.
- W4224509129 cites W2561135550 @default.
- W4224509129 cites W2593775298 @default.
- W4224509129 cites W2739252919 @default.
- W4224509129 cites W2766090477 @default.
- W4224509129 cites W2792522767 @default.
- W4224509129 cites W2800878103 @default.
- W4224509129 cites W2801936818 @default.
- W4224509129 cites W2801992158 @default.
- W4224509129 cites W2888377253 @default.
- W4224509129 cites W2901836732 @default.
- W4224509129 cites W2911642310 @default.
- W4224509129 cites W2917842677 @default.
- W4224509129 cites W2918077387 @default.
- W4224509129 cites W2949738667 @default.
- W4224509129 cites W2956616100 @default.
- W4224509129 cites W2965786813 @default.
- W4224509129 cites W2970078533 @default.
- W4224509129 cites W2971512351 @default.
- W4224509129 cites W2972823724 @default.
- W4224509129 cites W2980951331 @default.
- W4224509129 cites W2982725428 @default.
- W4224509129 cites W2995130603 @default.
- W4224509129 cites W3004307250 @default.
- W4224509129 cites W3012261821 @default.
- W4224509129 cites W3034962419 @default.
- W4224509129 cites W3052924402 @default.
- W4224509129 cites W3096025577 @default.
- W4224509129 cites W3126407038 @default.
- W4224509129 cites W4230340127 @default.
- W4224509129 doi "https://doi.org/10.1016/j.drugalcdep.2022.109473" @default.
- W4224509129 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35523113" @default.
- W4224509129 hasPublicationYear "2022" @default.
- W4224509129 type Work @default.
- W4224509129 citedByCount "1" @default.
- W4224509129 countsByYear W42245091292023 @default.
- W4224509129 crossrefType "journal-article" @default.
- W4224509129 hasAuthorship W4224509129A5014847345 @default.
- W4224509129 hasAuthorship W4224509129A5026094776 @default.
- W4224509129 hasAuthorship W4224509129A5036298172 @default.
- W4224509129 hasAuthorship W4224509129A5053276850 @default.
- W4224509129 hasAuthorship W4224509129A5054833763 @default.
- W4224509129 hasAuthorship W4224509129A5086006866 @default.
- W4224509129 hasBestOaLocation W42245091291 @default.
- W4224509129 hasConcept C104863432 @default.
- W4224509129 hasConcept C105795698 @default.
- W4224509129 hasConcept C126322002 @default.
- W4224509129 hasConcept C138816342 @default.
- W4224509129 hasConcept C159110408 @default.
- W4224509129 hasConcept C170493617 @default.
- W4224509129 hasConcept C194828623 @default.
- W4224509129 hasConcept C2426938 @default.
- W4224509129 hasConcept C2776315796 @default.
- W4224509129 hasConcept C2778750930 @default.
- W4224509129 hasConcept C2779148768 @default.
- W4224509129 hasConcept C2781063702 @default.
- W4224509129 hasConcept C2781072394 @default.
- W4224509129 hasConcept C2908647359 @default.
- W4224509129 hasConcept C2909024267 @default.
- W4224509129 hasConcept C3017944768 @default.
- W4224509129 hasConcept C33923547 @default.
- W4224509129 hasConcept C42219234 @default.
- W4224509129 hasConcept C44249647 @default.
- W4224509129 hasConcept C512399662 @default.
- W4224509129 hasConcept C529928208 @default.
- W4224509129 hasConcept C71924100 @default.
- W4224509129 hasConcept C98274493 @default.
- W4224509129 hasConcept C99454951 @default.
- W4224509129 hasConceptScore W4224509129C104863432 @default.
- W4224509129 hasConceptScore W4224509129C105795698 @default.
- W4224509129 hasConceptScore W4224509129C126322002 @default.
- W4224509129 hasConceptScore W4224509129C138816342 @default.
- W4224509129 hasConceptScore W4224509129C159110408 @default.
- W4224509129 hasConceptScore W4224509129C170493617 @default.
- W4224509129 hasConceptScore W4224509129C194828623 @default.