FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4224589310> ?p ?o ?g. }

• W4224589310 abstract "Background: Porcine heart and bovine pericardium valves, which are collagen-based with relatively little elastin, have been broadly utilized to construct bioprosthetic heart valves (BHVs). With a larger proportion of elastin, the pulmonary visceral pleura (PVP) has greater elasticity and could potentially serve as an advantageous biomaterial for the construction/repair of BHVs. The question of how the aortic valve's performance is affected by its bending rigidity has not been well studied. Methods: Based on the stress-strain relationships of the pericardium and PVP determined by planar uni-axial tests, a three-dimensional (3D) computational fluid-structure interaction (FSI) framework is employed to numerically investigate the aortic valve's performance by considering three different cases with Young's modulus as follows: E=375 , 750 , and 1500 kPa, respectively. Results: The stroke volumes are 112, 99.6, and 91.4 ml as Young's modulus increases from 375 to 750 and 1500 kPa, respectively. Peak geometric opening area (GOA) values are 2.3, 2.2, and 2.0 cm2 for E=375 , 750, and 1500 kPa, respectively. The maximum value of the aortic leaflet stress is about 271 kPa for E=375 kPa, and it increases to about 383 and 540 kPa for E=750 and 1500 kPa in the belly region at the peak systole, while it reduces from 550 kPa to 450 and 400 kPa for E=375 , 750, and 1500 kPa, respectively, at the instant of peak water-hammer. Conclusion: A more compliant PVP aortic leaflet valve with a smaller Young's modulus, E , has a higher cardiac output, larger GOA, and lower hemodynamic resistance. Most importantly, the aortic leaflet stresses are substantially lower in the belly region within the higher compliance PVP aortic valve tissue during the systole phase, even though some stress increase is also found during the fast-closing phase due to the water-hammer effect similar to that in the pericardial tissue. Future clinical studies will be conducted to test the hypothesis that the PVP-based valve leaflets with higher compliance will have lower fatigue or calcification rates due to the overall lower stress." @default.
• W4224589310 created "2022-04-27" @default.
• W4224589310 creator A5026060144 @default.
• W4224589310 creator A5068904779 @default.
• W4224589310 creator A5081782138 @default.
• W4224589310 creator A5086452343 @default.
• W4224589310 date "2022-04-26" @default.
• W4224589310 modified "2023-10-18" @default.
• W4224589310 title "Aortic Leaflet Stresses Are Substantially Lower Using Pulmonary Visceral Pleura Than Pericardial Tissue" @default.
• W4224589310 cites W1175704214 @default.
• W4224589310 cites W1543715150 @default.
• W4224589310 cites W1580797149 @default.
• W4224589310 cites W1970267065 @default.
• W4224589310 cites W1985393587 @default.
• W4224589310 cites W1996771593 @default.
• W4224589310 cites W2009204009 @default.
• W4224589310 cites W2010118207 @default.
• W4224589310 cites W2033114927 @default.
• W4224589310 cites W2050210997 @default.
• W4224589310 cites W2060833243 @default.
• W4224589310 cites W2068470549 @default.
• W4224589310 cites W2077889232 @default.
• W4224589310 cites W2078034298 @default.
• W4224589310 cites W2098510103 @default.
• W4224589310 cites W2106796962 @default.
• W4224589310 cites W2126464383 @default.
• W4224589310 cites W2127226038 @default.
• W4224589310 cites W2156922522 @default.
• W4224589310 cites W2346879305 @default.
• W4224589310 cites W2552376975 @default.
• W4224589310 cites W2554231017 @default.
• W4224589310 cites W2801499546 @default.
• W4224589310 cites W2954350064 @default.
• W4224589310 cites W2980403721 @default.
• W4224589310 cites W2990528997 @default.
• W4224589310 cites W2993456875 @default.
• W4224589310 cites W2994695180 @default.
• W4224589310 cites W3032935701 @default.
• W4224589310 cites W3105922237 @default.
• W4224589310 cites W3123723379 @default.
• W4224589310 cites W384006447 @default.
• W4224589310 cites W95347834 @default.
• W4224589310 cites W1537524068 @default.
• W4224589310 doi "https://doi.org/10.3389/fbioe.2022.869095" @default.
• W4224589310 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35557866" @default.
• W4224589310 hasPublicationYear "2022" @default.
• W4224589310 type Work @default.
• W4224589310 citedByCount "1" @default.
• W4224589310 countsByYear W42245893102023 @default.
• W4224589310 crossrefType "journal-article" @default.
• W4224589310 hasAuthorship W4224589310A5026060144 @default.
• W4224589310 hasAuthorship W4224589310A5068904779 @default.
• W4224589310 hasAuthorship W4224589310A5081782138 @default.
• W4224589310 hasAuthorship W4224589310A5086452343 @default.
• W4224589310 hasBestOaLocation W42245893101 @default.
• W4224589310 hasConcept C105702510 @default.
• W4224589310 hasConcept C136229726 @default.
• W4224589310 hasConcept C142724271 @default.
• W4224589310 hasConcept C159985019 @default.
• W4224589310 hasConcept C164705383 @default.
• W4224589310 hasConcept C192562407 @default.
• W4224589310 hasConcept C193867417 @default.
• W4224589310 hasConcept C196029304 @default.
• W4224589310 hasConcept C2776229121 @default.
• W4224589310 hasConcept C2778875491 @default.
• W4224589310 hasConcept C2779869378 @default.
• W4224589310 hasConcept C2779980429 @default.
• W4224589310 hasConcept C2780714102 @default.
• W4224589310 hasConcept C71924100 @default.
• W4224589310 hasConceptScore W4224589310C105702510 @default.
• W4224589310 hasConceptScore W4224589310C136229726 @default.
• W4224589310 hasConceptScore W4224589310C142724271 @default.
• W4224589310 hasConceptScore W4224589310C159985019 @default.
• W4224589310 hasConceptScore W4224589310C164705383 @default.
• W4224589310 hasConceptScore W4224589310C192562407 @default.
• W4224589310 hasConceptScore W4224589310C193867417 @default.
• W4224589310 hasConceptScore W4224589310C196029304 @default.
• W4224589310 hasConceptScore W4224589310C2776229121 @default.
• W4224589310 hasConceptScore W4224589310C2778875491 @default.
• W4224589310 hasConceptScore W4224589310C2779869378 @default.
• W4224589310 hasConceptScore W4224589310C2779980429 @default.
• W4224589310 hasConceptScore W4224589310C2780714102 @default.
• W4224589310 hasConceptScore W4224589310C71924100 @default.
• W4224589310 hasFunder F4320332161 @default.
• W4224589310 hasLocation W42245893101 @default.
• W4224589310 hasLocation W42245893102 @default.
• W4224589310 hasLocation W42245893103 @default.
• W4224589310 hasOpenAccess W4224589310 @default.
• W4224589310 hasPrimaryLocation W42245893101 @default.
• W4224589310 hasRelatedWork W1967241601 @default.
• W4224589310 hasRelatedWork W1990132939 @default.
• W4224589310 hasRelatedWork W2006431693 @default.
• W4224589310 hasRelatedWork W2020340785 @default.
• W4224589310 hasRelatedWork W2055568118 @default.
• W4224589310 hasRelatedWork W2063778609 @default.
• W4224589310 hasRelatedWork W2472117937 @default.
• W4224589310 hasRelatedWork W2595859023 @default.
• W4224589310 hasRelatedWork W2606221433 @default.
• W4224589310 hasRelatedWork W4224589310 @default.
• W4224589310 hasVolume "10" @default.

• next