FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4224596113> ?p ?o ?g. }

• W4224596113 endingPage "1079" @default.
• W4224596113 startingPage "1079" @default.
• W4224596113 abstract "Loiasis, caused by the filarial nematode Loa loa, is endemic in Central and West Africa. Loa loa has been associated with severe adverse reactions in high Loa-infected individuals receiving ivermectin during mass drug administration programs for the control of onchocerciasis and lymphatic filariasis. Diagnosis of loiasis still depends on microscopy in blood samples, but this is not effective for large-scale surveys. New diagnostics methods for loiasis are urgently needed. Previously, we developed a colorimetric high-sensitive and species-specific LAMP for Loa loa DNA detection. Here, we evaluate it in a set of 100 field-collected clinical samples stored as dried blood spots. In addition, Loa loa-LAMP was also evaluated in real-time testing and compared with microscopy and a specific PCR/nested PCR. A simple saponin/Chelex-based method was used to extract DNA. Colorimetric and real-time LAMP assays detected more samples with microscopy-confirmed Loa loa and Loa loa/Mansonella perstans mixed infections than PCR/nested-PCR. Samples with the highest Loa loa microfilariae counts were amplified faster in real-time LAMP assays. Our Loa loa-LAMP could be a promising molecular tool for the easy, rapid and accurate screening of patients for loiasis in endemic areas with low-resource settings. The real-time testing (feasible in a handheld device) could be very useful to rule out high-microfilariae loads in infected patients." @default.
• W4224596113 created "2022-04-27" @default.
• W4224596113 creator A5004783025 @default.
• W4224596113 creator A5006503984 @default.
• W4224596113 creator A5023659030 @default.
• W4224596113 creator A5034130065 @default.
• W4224596113 creator A5046566470 @default.
• W4224596113 creator A5053924318 @default.
• W4224596113 creator A5054836364 @default.
• W4224596113 creator A5056337927 @default.
• W4224596113 creator A5061763924 @default.
• W4224596113 creator A5067529107 @default.
• W4224596113 creator A5073848974 @default.
• W4224596113 creator A5074517328 @default.
• W4224596113 date "2022-04-25" @default.
• W4224596113 modified "2023-10-18" @default.
• W4224596113 title "Colorimetric and Real-Time Loop-Mediated Isothermal Amplification (LAMP) for Detection of Loa loa DNA in Human Blood Samples" @default.
• W4224596113 cites W1500247208 @default.
• W4224596113 cites W163010470 @default.
• W4224596113 cites W1838568970 @default.
• W4224596113 cites W1854087605 @default.
• W4224596113 cites W1932301938 @default.
• W4224596113 cites W1975801865 @default.
• W4224596113 cites W1985175515 @default.
• W4224596113 cites W1987091168 @default.
• W4224596113 cites W1987880853 @default.
• W4224596113 cites W1994278994 @default.
• W4224596113 cites W2013660563 @default.
• W4224596113 cites W2021904910 @default.
• W4224596113 cites W2022012410 @default.
• W4224596113 cites W2035219286 @default.
• W4224596113 cites W2049768104 @default.
• W4224596113 cites W2063533401 @default.
• W4224596113 cites W2065098811 @default.
• W4224596113 cites W2072243249 @default.
• W4224596113 cites W2084632839 @default.
• W4224596113 cites W2095315281 @default.
• W4224596113 cites W2095917140 @default.
• W4224596113 cites W2105275554 @default.
• W4224596113 cites W2120017448 @default.
• W4224596113 cites W2129355263 @default.
• W4224596113 cites W2130213398 @default.
• W4224596113 cites W2148765503 @default.
• W4224596113 cites W2155358648 @default.
• W4224596113 cites W2156380818 @default.
• W4224596113 cites W2156433666 @default.
• W4224596113 cites W2163512019 @default.
• W4224596113 cites W2174781316 @default.
• W4224596113 cites W2183279756 @default.
• W4224596113 cites W2225710478 @default.
• W4224596113 cites W2234337445 @default.
• W4224596113 cites W2559470376 @default.
• W4224596113 cites W2733992941 @default.
• W4224596113 cites W2740872866 @default.
• W4224596113 cites W2761321182 @default.
• W4224596113 cites W2767594581 @default.
• W4224596113 cites W2780860670 @default.
• W4224596113 cites W2782894713 @default.
• W4224596113 cites W2783347320 @default.
• W4224596113 cites W2789002710 @default.
• W4224596113 cites W2804827168 @default.
• W4224596113 cites W2809494364 @default.
• W4224596113 cites W2897402248 @default.
• W4224596113 cites W2898806417 @default.
• W4224596113 cites W2958194661 @default.
• W4224596113 cites W2963771773 @default.
• W4224596113 cites W2982486238 @default.
• W4224596113 cites W3022655241 @default.
• W4224596113 cites W3045202313 @default.
• W4224596113 cites W3119417145 @default.
• W4224596113 cites W4210868551 @default.
• W4224596113 cites W4229549340 @default.
• W4224596113 cites W4243936225 @default.
• W4224596113 doi "https://doi.org/10.3390/diagnostics12051079" @default.
• W4224596113 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35626235" @default.
• W4224596113 hasPublicationYear "2022" @default.
• W4224596113 type Work @default.
• W4224596113 citedByCount "1" @default.
• W4224596113 crossrefType "journal-article" @default.
• W4224596113 hasAuthorship W4224596113A5004783025 @default.
• W4224596113 hasAuthorship W4224596113A5006503984 @default.
• W4224596113 hasAuthorship W4224596113A5023659030 @default.
• W4224596113 hasAuthorship W4224596113A5034130065 @default.
• W4224596113 hasAuthorship W4224596113A5046566470 @default.
• W4224596113 hasAuthorship W4224596113A5053924318 @default.
• W4224596113 hasAuthorship W4224596113A5054836364 @default.
• W4224596113 hasAuthorship W4224596113A5056337927 @default.
• W4224596113 hasAuthorship W4224596113A5061763924 @default.
• W4224596113 hasAuthorship W4224596113A5067529107 @default.
• W4224596113 hasAuthorship W4224596113A5073848974 @default.
• W4224596113 hasAuthorship W4224596113A5074517328 @default.
• W4224596113 hasBestOaLocation W42245961131 @default.
• W4224596113 hasConcept C153911025 @default.
• W4224596113 hasConcept C165901193 @default.
• W4224596113 hasConcept C167871757 @default.
• W4224596113 hasConcept C203014093 @default.
• W4224596113 hasConcept C2776031002 @default.
• W4224596113 hasConcept C2776158911 @default.

• next