Matches in SemOpenAlex for { <https://semopenalex.org/work/W4224661797> ?p ?o ?g. }
- W4224661797 abstract "Alzheimer’s disease (AD) is the most common neurodegenerative disease and is characterized by progressive cognitive dysfunction and memory loss in the elderly, which seriously affects the quality of their lives. Currently, the pathogenesis of AD remains unclear. Molecular biologists have proposed a variety of hypotheses, including the amyloid-β hypothesis, tau hyperphosphorylation hypothesis, cholinergic neuron injury, inflammation caused by an abnormal immune response, and gene mutation. Drugs based on these pathological studies, including cholinesterase inhibitors and N-methyl-D-aspartate receptor antagonists, have achieved a certain level of efficacy but are far from meeting clinical needs. In the recent years, some important advances have been made in the traditional Chinese medicine treatment of AD. Erigeron breviscapus (Vant.) Hand-Mazz. (EBHM) is an important medicinal plant distributed in Yunnan Province, China. Studies have shown that EBHM and its active ingredients have a variety of pharmacological effects with good therapeutic effects and wide application prospects for cognitive disability-related diseases. However, to our best knowledge, only few review articles have been published on the anti-AD effects of EBHM. Through a literature review, we identified the possible pathogenesis of AD, discussed the cultivation and phytochemistry of EBHM, and summarized the pharmacological mechanism of EBHM and its active ingredients in the treatment of AD to provide suggestions regarding anti-AD therapy as well as a broader insight into the therapeutic potential of EBHM." @default.
- W4224661797 created "2022-04-27" @default.
- W4224661797 creator A5009333117 @default.
- W4224661797 creator A5051017507 @default.
- W4224661797 date "2022-04-26" @default.
- W4224661797 modified "2023-09-26" @default.
- W4224661797 title "Erigeron breviscapus (Vant.) Hand-Mazz.: A Promising Natural Neuroprotective Agent for Alzheimer’s Disease" @default.
- W4224661797 cites W1494211647 @default.
- W4224661797 cites W1498115555 @default.
- W4224661797 cites W1528275131 @default.
- W4224661797 cites W1882566069 @default.
- W4224661797 cites W1963993567 @default.
- W4224661797 cites W1973296024 @default.
- W4224661797 cites W1973733191 @default.
- W4224661797 cites W1987076477 @default.
- W4224661797 cites W1989689426 @default.
- W4224661797 cites W1995447460 @default.
- W4224661797 cites W2000908311 @default.
- W4224661797 cites W2003970507 @default.
- W4224661797 cites W2015234847 @default.
- W4224661797 cites W2040423354 @default.
- W4224661797 cites W2041547815 @default.
- W4224661797 cites W2043201662 @default.
- W4224661797 cites W2051388479 @default.
- W4224661797 cites W2051401733 @default.
- W4224661797 cites W2052362708 @default.
- W4224661797 cites W2052761136 @default.
- W4224661797 cites W2060214041 @default.
- W4224661797 cites W2060805703 @default.
- W4224661797 cites W2061333828 @default.
- W4224661797 cites W2061765230 @default.
- W4224661797 cites W2069893872 @default.
- W4224661797 cites W2073656988 @default.
- W4224661797 cites W2074661552 @default.
- W4224661797 cites W2082540127 @default.
- W4224661797 cites W2084060787 @default.
- W4224661797 cites W2094640306 @default.
- W4224661797 cites W2109984042 @default.
- W4224661797 cites W2118478089 @default.
- W4224661797 cites W2162878517 @default.
- W4224661797 cites W2164490896 @default.
- W4224661797 cites W2168499550 @default.
- W4224661797 cites W2239903496 @default.
- W4224661797 cites W2261085470 @default.
- W4224661797 cites W2329336071 @default.
- W4224661797 cites W2345260273 @default.
- W4224661797 cites W2366404060 @default.
- W4224661797 cites W2373671840 @default.
- W4224661797 cites W2412202264 @default.
- W4224661797 cites W2418082769 @default.
- W4224661797 cites W2467253808 @default.
- W4224661797 cites W2472736674 @default.
- W4224661797 cites W2492045666 @default.
- W4224661797 cites W2550850084 @default.
- W4224661797 cites W2575337706 @default.
- W4224661797 cites W2600703024 @default.
- W4224661797 cites W2613251848 @default.
- W4224661797 cites W2617788655 @default.
- W4224661797 cites W2738888781 @default.
- W4224661797 cites W2739182934 @default.
- W4224661797 cites W2739628150 @default.
- W4224661797 cites W2742783690 @default.
- W4224661797 cites W2743513023 @default.
- W4224661797 cites W2755558750 @default.
- W4224661797 cites W2768412315 @default.
- W4224661797 cites W2774284160 @default.
- W4224661797 cites W2791553480 @default.
- W4224661797 cites W2793391328 @default.
- W4224661797 cites W2793673664 @default.
- W4224661797 cites W2797133397 @default.
- W4224661797 cites W2799864931 @default.
- W4224661797 cites W2800060797 @default.
- W4224661797 cites W2805257646 @default.
- W4224661797 cites W2807564415 @default.
- W4224661797 cites W2887698793 @default.
- W4224661797 cites W2888993029 @default.
- W4224661797 cites W2890547275 @default.
- W4224661797 cites W2892135048 @default.
- W4224661797 cites W2892312375 @default.
- W4224661797 cites W2893130459 @default.
- W4224661797 cites W2907547898 @default.
- W4224661797 cites W2908803078 @default.
- W4224661797 cites W2913751428 @default.
- W4224661797 cites W2922471618 @default.
- W4224661797 cites W2939808570 @default.
- W4224661797 cites W2958665365 @default.
- W4224661797 cites W2969869660 @default.
- W4224661797 cites W2984563923 @default.
- W4224661797 cites W2990871652 @default.
- W4224661797 cites W2993041426 @default.
- W4224661797 cites W2997032704 @default.
- W4224661797 cites W3000635098 @default.
- W4224661797 cites W3006091262 @default.
- W4224661797 cites W3006572353 @default.
- W4224661797 cites W3007324781 @default.
- W4224661797 cites W3023832122 @default.
- W4224661797 cites W3048901815 @default.
- W4224661797 cites W3082199339 @default.
- W4224661797 cites W3088400247 @default.
- W4224661797 cites W3090944540 @default.