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- W4224880041 endingPage "102591" @default.
- W4224880041 startingPage "102591" @default.
- W4224880041 abstract "Antimicrobial coatings on metallic surfaces are rapidly emerging to combat bacterial pathogens. The excess use of conventional antibiotics increases the number of resistant strains at an alarming rate, which in turn leads to detrimental implications in the healthcare sector. Hence, it is of great importance in developing a new class of material with inherent bactericidal activity and good biocompatibility. In the present study, we have modified the aluminium surfaces by a coating of graphene oxide (GO) due to its excellent physicochemical properties, water dispersity and low cytotoxicity. Coatings were developed through facile and enviornment-friendly transfer method. The antimicrobial properties of GO coated aluminium are investigated against Gram-negative strain E. coli through agar plate counting and ‘Live/Dead’ fluorescence staining. Further, to shed light into the mechanism of antibacterial activity of GO at the molecular level, we have performed X-ray reflectivity (XRR) study considering a phospholipid multilayer as a model system to mimic bacteria cell membrane. Results show a significant bactericidal activity of the GO coatings compared to uncoated aluminium with lower concentration showing slightly better antibacterial property due to higher roughness. The obtained results may pave the way for engineering graphene-based antimicrobial coatings on a material surface using an easy, environment-friendly, cost-effective and straight forward processing route." @default.
- W4224880041 created "2022-04-27" @default.
- W4224880041 creator A5038034267 @default.
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- W4224880041 date "2022-11-01" @default.
- W4224880041 modified "2023-10-06" @default.
- W4224880041 title "Graphene oxide coated aluminium as an efficient antibacterial surface" @default.
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- W4224880041 doi "https://doi.org/10.1016/j.eti.2022.102591" @default.
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