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- W4224942325 abstract "To date, hydroxychloroquine (HCQ) is a well-established antimalarial and immunomodulatory drug used as a treatment for several autoimmune and infectious diseases including rheumatoid arthritis, lupus erythematosus, and malaria [1], [2]. Recently, HCQ has been used as pre-/postexposure prophylaxis and treatment for the coronavirus disease 2019 (COVID-19) [3], [4], [5], [6]. However, despite the potential antiviral effects and its anti-inflammatory profile, the results based on clinical studies regarding HCQ as a treatment for SARS-CoV-2 are contradictory, and main concerns exist for its efficacy and safety profile [1], [2], [3], [7], [8]. In addition, studies have shown that the benefits of treating SARS-CoV-2 patients are limited and do not seem to outweigh side effects [2], [3], [5], [7]. Thus, the World Health Organization (WHO) no longer recommends HCQ to prevent or treat patients with SARS-CoV-2 [9]. Among common side effects, HCQ can cause gastrointestinal discomfort, headache, and dizziness, but also more severe side effects such as cardiotoxicity and ocular toxicity [1], [3], [6]. Regarding ocular toxicity, manifestations can be corneal deposits, ciliary body dysfunction, posterior subcapsular lens opacity, and retinopathy [10], [11]. Symptoms of an HCQ retinopathy can include blurred vision, loss of night vision, and partial central or peripheral loss of vision [10]." @default.
- W4224942325 created "2022-04-28" @default.
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- W4224942325 date "2022-04-01" @default.
- W4224942325 modified "2023-09-27" @default.
- W4224942325 title "Decrease in Visual Acuity in a 77-Year-old Woman with Age-Related Macular Degeneration after a SARS-CoV-2 Infection Treated with Hydroxychloroquine" @default.
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- W4224942325 doi "https://doi.org/10.1055/a-1766-7035" @default.
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