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- W4224952170 abstract "The recent advances in molecular methods and data processing have facilitated research on anisakid nematodes. While most research efforts were made regarding the genus Anisakis, since this genus is held responsible for the majority of reported clinical signs, there is still a demand for data on the genus Pseudoterranova. Several case studies of severe invasive anisakidosis affecting various organs caused by species of the P. decipiens complex have been described. To better understand the way these parasites might infest their fish host, we examined whether parasite location within the fish host affects gene expression. A de novo assembly of the transcriptome of Pseudoterranova bulbosa, isolated from North Atlantic cod, was analysed for patterns of differential gene expression between samples taken from liver and viscera. We additionally searched for homologs to known nematode allergens, to give a first estimate of the potential allergenicity of P. bulbosa. There was a subtle difference in the gene expression of samples taken from liver and viscera. Seventy genes were differentially expressed, 32 genes were upregulated in parasites isolated from liver and 38 genes were upregulated in parasites from viscera. Homologs of five nematode allergens were identified among the genes expressed by P. bulbosa. Our transcriptome of P. bulbosa will be a valuable resource for further meta-analyses and resequencing projects." @default.
- W4224952170 created "2022-04-28" @default.
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- W4224952170 date "2022-04-27" @default.
- W4224952170 modified "2023-10-16" @default.
- W4224952170 title "Gene expression and allergenic potential of <i>Pseudoterranova bulbosa</i> L3 from different infection sites in North Atlantic cod ( <i>Gadus morhua</i> )" @default.
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- W4224952170 doi "https://doi.org/10.1111/jfd.13630" @default.
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- W4224952170 hasPublicationYear "2022" @default.
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