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- W4224955950 abstract "Gene therapy has the potential to transform lives, as over 3000 genes have been associated with disease-causing mutations. CRISPR/Cas9 technology can perform site-specific editing of the human genome and potentially treat many diseases. However, effective delivery of the CRISPR/Cas9 gene editing system remains one major obstacle for affordable treatments. Several methods have been developed to improve CRISPR/Cas9 delivery, including polyplexes, or complexes formed between polymer vehicles and gene and/or protein cargo." @default.
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- W4224955950 date "2022-02-01" @default.
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- W4224955950 title "Raman spectro-microscopy to improve gene therapy vehicle design for CRISPR/cas9 delivery" @default.
- W4224955950 doi "https://doi.org/10.1016/j.bpj.2021.11.687" @default.
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