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• W4224990465 endingPage "549" @default.
• W4224990465 startingPage "533" @default.
• W4224990465 abstract "Cytosolic ABA Receptor Kinases (CARKs) play a pivotal role in abscisic acid (ABA)-dependent pathway in response to dehydration, but their regulatory mechanism in ABA signaling remains unexplored. In this study, we showed that CARK4/5 of CARK family physically interacted with ABA receptors (RCARs/PYR1/PYLs), including RCAR3, RCAR11-RCAR14, while CARK2/7/11 only interacted with RCAR11-RCAR14, but not RCAR3. It indicates that the members in CARK family function redundantly and differentially in ABA signaling. RCAR12 can form heterodimer with RCAR3 in vitro and in vivo. Moreover, the members of CARK family can form homodimer or heterodimer in a kinase activity dependent manner. ITC (isothermal titration calorimetry) analysis demonstrated that the phosphorylation of RCAR12 by CARK1 enhanced the ABA binding affinity. The phosphor-mimic RCAR12T105D significantly displayed ABA-induced inhibition of the phosphatase ABI1 (ABA insensitive 1) activity, leading to upregulation of ABA-responsive genes RD29A and RD29B in cark157:RCAR12T105D transgenic plants, which exhibited ABA hypersensitive phenotype. The transcription factor ABI5 (ABA insensitive 5) activates the transcriptions of CARK1 and CARK3 by binding to ABA-response elements (ABREs) of their promoters. Collectively, our data imply that the dimeric CARKs phosphorylate homodimer or heterodimer ABA receptors, leading to monomerization for triggering ABA responses in Arabidopsis." @default.
• W4224990465 created "2022-04-28" @default.
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• W4224990465 date "2022-04-27" @default.
• W4224990465 modified "2023-10-12" @default.
• W4224990465 title "Monomerization of abscisic acid receptors through CARKs‐mediated phosphorylation" @default.
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• W4224990465 cites W1966613025 @default.
• W4224990465 cites W1974131529 @default.
• W4224990465 cites W1974439236 @default.
• W4224990465 cites W1975604769 @default.
• W4224990465 cites W1978838242 @default.
• W4224990465 cites W1984017573 @default.
• W4224990465 cites W1992903652 @default.
• W4224990465 cites W1994410233 @default.
• W4224990465 cites W1997038372 @default.
• W4224990465 cites W2000555534 @default.
• W4224990465 cites W2010357923 @default.
• W4224990465 cites W2022682338 @default.
• W4224990465 cites W2026011395 @default.
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• W4224990465 cites W2054547140 @default.
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• W4224990465 cites W2099204445 @default.
• W4224990465 cites W2106541825 @default.
• W4224990465 cites W2107345958 @default.
• W4224990465 cites W2109411650 @default.
• W4224990465 cites W2110561077 @default.
• W4224990465 cites W2114900530 @default.
• W4224990465 cites W2116122104 @default.
• W4224990465 cites W2124422581 @default.
• W4224990465 cites W2134562769 @default.
• W4224990465 cites W2142704168 @default.
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• W4224990465 cites W2156700158 @default.
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• W4224990465 cites W2165628747 @default.
• W4224990465 cites W2167784171 @default.
• W4224990465 cites W2170938681 @default.
• W4224990465 cites W2272955058 @default.
• W4224990465 cites W2402240536 @default.
• W4224990465 cites W2406618641 @default.
• W4224990465 cites W2415952796 @default.
• W4224990465 cites W2510350523 @default.
• W4224990465 cites W2582506618 @default.
• W4224990465 cites W2604973478 @default.
• W4224990465 cites W2752431554 @default.
• W4224990465 cites W2761983477 @default.
• W4224990465 cites W2765629940 @default.
• W4224990465 cites W2766590917 @default.
• W4224990465 cites W2778077257 @default.
• W4224990465 cites W2794416643 @default.
• W4224990465 cites W2807178079 @default.
• W4224990465 cites W2898972668 @default.
• W4224990465 cites W2907526377 @default.
• W4224990465 cites W2907933728 @default.
• W4224990465 cites W2934110912 @default.
• W4224990465 cites W2953411320 @default.
• W4224990465 cites W2969673725 @default.
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• W4224990465 doi "https://doi.org/10.1111/nph.18149" @default.
• W4224990465 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35388459" @default.
• W4224990465 hasPublicationYear "2022" @default.
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