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- W4224996711 abstract "Abstract A novel bis ‐heterocyclic system encompassing the 1,2‐dihydro‐3 H ‐pyrrolo[3,4‐ b ]indolizin‐3‐one and 1,5‐disubstituted tetrazole moieties was designed, synthesized, and evaluated as a Copper (II) recognizing agent. This was achieved by exploiting the optical characteristics of indolizine and the copper recognizing activity of tetrazoles. For the preparation of these compounds, a novel and simple synthetic strategy consisting in a double one‐pot process involving four‐step reactions was developed. The first process is a one‐pot five component reaction by using propargylamine as a bifunctional reactant to access the key intermediate, the N ‐acylated tetrazole. Consequently, N ‐acylated tetrazole was subjected to a one‐pot three component reaction, consisting in a bimolecular nucleophilic substitution followed of a domino process to afford the target compounds. The photophysical properties of the obtained bis ‐heterocycles were evaluated against copper (II) addition." @default.
- W4224996711 created "2022-04-28" @default.
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- W4224996711 date "2022-05-23" @default.
- W4224996711 modified "2023-10-16" @default.
- W4224996711 title "Synthesis of 1,5‐Disubstituted Tetrazole−Indolizine <i>Bis</i> ‐Heterocycles and Their Copper (II) Recognizing Properties" @default.
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- W4224996711 doi "https://doi.org/10.1002/ejoc.202200230" @default.
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