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• W4225000161 abstract "This report describes an efficient method for one-pot, three-component coupling of aldehydes, β-ketoesters/β-diketone, and urea/thiourea catalyzed by N-(phenylsulfonyl)benzene sulfonamide (NPBSA) as efficient organocatalyst to afford the corresponding 3,4-dihydropyrimidine-2(1H)-ones/thiones via Biginelli condensation. Novel catalyst, high yields, quick reaction time, solvent-free environment, simple workup, and the ability to tolerate a variety of functional groups are some of the advantages of the current method, providing economic and environmental benefits. The present work also includes the synthesis of active pharmaceutical ingredient Piperasterol as application of the method." @default.
• W4225000161 created "2022-04-29" @default.
• W4225000161 creator A5046007050 @default.
• W4225000161 creator A5056224849 @default.
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• W4225000161 date "2022-04-27" @default.
• W4225000161 modified "2023-09-29" @default.
• W4225000161 title "<i>N</i>-(Phenylsulfonyl)Benzenesulfonamide: A New Organocatalyst for One-Pot, Solvent-Free Synthesis of Biginelli’s 3,4-Dihydropyrimidine-2(1<i>H</i>)-Thiones" @default.
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• W4225000161 doi "https://doi.org/10.1080/10406638.2022.2067191" @default.
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