Matches in SemOpenAlex for { <https://semopenalex.org/work/W4225015064> ?p ?o ?g. }
- W4225015064 abstract "When fish are under oxidative stress, levels of reactive oxygen species (ROS) are chronically elevated, which play a crucial role in fish innate immunity. In the present study, the mechanism by which betaine regulates ROS production via Wnt10b/β-catenin signaling was investigated in zebrafish liver. Our results showed that betaine enrichment of diet at 0.1, 0.2 and 0.4 g/kg induced Wnt10b and β-catenin gene expression, but suppressed GSK-3β expression in zebrafish liver. In addition, the content of superoxide anion (O2·-), hydrogen peroxide (H2O2) and hydroxyl radical (·OH) was decreased by all of the experimental betaine treatments. However, betaine enrichment of diet at 0.1, 0.2 and 0.4 g/kg enhanced gene expression and activity of superoxide dismutase (SOD), glutathione peroxidase (GSH-PX) and catalase (CAT) in zebrafish liver. In addition, Wnt10b RNA was further interfered in zebrafish, and the results of Wnt10b RNAi indicated that Wnt10b plays a key role in regulating ROS production and antioxidant enzyme activity. In conclusion, betaine can inhibit ROS production in zebrafish liver through the Wnt10b/β-catenin signaling pathway." @default.
- W4225015064 created "2022-04-29" @default.
- W4225015064 creator A5004629089 @default.
- W4225015064 creator A5021983750 @default.
- W4225015064 creator A5024800181 @default.
- W4225015064 creator A5026475770 @default.
- W4225015064 creator A5053018112 @default.
- W4225015064 creator A5057281199 @default.
- W4225015064 date "2022-04-28" @default.
- W4225015064 modified "2023-10-18" @default.
- W4225015064 title "Betaine Regulates the Production of Reactive Oxygen Species Through Wnt10b Signaling in the Liver of Zebrafish" @default.
- W4225015064 cites W1577149434 @default.
- W4225015064 cites W1619859117 @default.
- W4225015064 cites W1889155473 @default.
- W4225015064 cites W1962867466 @default.
- W4225015064 cites W1966589861 @default.
- W4225015064 cites W1985548941 @default.
- W4225015064 cites W1998417945 @default.
- W4225015064 cites W2001422326 @default.
- W4225015064 cites W2012197375 @default.
- W4225015064 cites W2015974087 @default.
- W4225015064 cites W2017668082 @default.
- W4225015064 cites W2027728914 @default.
- W4225015064 cites W2039248606 @default.
- W4225015064 cites W2047429667 @default.
- W4225015064 cites W2051930121 @default.
- W4225015064 cites W2061380592 @default.
- W4225015064 cites W2064620988 @default.
- W4225015064 cites W2068483959 @default.
- W4225015064 cites W2070446839 @default.
- W4225015064 cites W2085886216 @default.
- W4225015064 cites W2090636859 @default.
- W4225015064 cites W2106943004 @default.
- W4225015064 cites W2107277218 @default.
- W4225015064 cites W2107651627 @default.
- W4225015064 cites W2108962195 @default.
- W4225015064 cites W2109955944 @default.
- W4225015064 cites W2119284420 @default.
- W4225015064 cites W2128635872 @default.
- W4225015064 cites W2140126848 @default.
- W4225015064 cites W2144796426 @default.
- W4225015064 cites W2161085054 @default.
- W4225015064 cites W2170582708 @default.
- W4225015064 cites W2192080449 @default.
- W4225015064 cites W2208123523 @default.
- W4225015064 cites W2346892681 @default.
- W4225015064 cites W2509513888 @default.
- W4225015064 cites W2527958556 @default.
- W4225015064 cites W2737430199 @default.
- W4225015064 cites W2795430688 @default.
- W4225015064 cites W2801153227 @default.
- W4225015064 cites W2809933682 @default.
- W4225015064 cites W2894807859 @default.
- W4225015064 cites W2916753152 @default.
- W4225015064 cites W4248948140 @default.
- W4225015064 cites W4293247451 @default.
- W4225015064 doi "https://doi.org/10.3389/fphys.2022.877178" @default.
- W4225015064 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35574489" @default.
- W4225015064 hasPublicationYear "2022" @default.
- W4225015064 type Work @default.
- W4225015064 citedByCount "1" @default.
- W4225015064 countsByYear W42250150642023 @default.
- W4225015064 crossrefType "journal-article" @default.
- W4225015064 hasAuthorship W4225015064A5004629089 @default.
- W4225015064 hasAuthorship W4225015064A5021983750 @default.
- W4225015064 hasAuthorship W4225015064A5024800181 @default.
- W4225015064 hasAuthorship W4225015064A5026475770 @default.
- W4225015064 hasAuthorship W4225015064A5053018112 @default.
- W4225015064 hasAuthorship W4225015064A5057281199 @default.
- W4225015064 hasBestOaLocation W42250150641 @default.
- W4225015064 hasConcept C104317684 @default.
- W4225015064 hasConcept C153911025 @default.
- W4225015064 hasConcept C181199279 @default.
- W4225015064 hasConcept C185592680 @default.
- W4225015064 hasConcept C2775838275 @default.
- W4225015064 hasConcept C2776151105 @default.
- W4225015064 hasConcept C2776878037 @default.
- W4225015064 hasConcept C2777248517 @default.
- W4225015064 hasConcept C2778004101 @default.
- W4225015064 hasConcept C2778979269 @default.
- W4225015064 hasConcept C2780795997 @default.
- W4225015064 hasConcept C48349386 @default.
- W4225015064 hasConcept C538909803 @default.
- W4225015064 hasConcept C55493867 @default.
- W4225015064 hasConcept C86803240 @default.
- W4225015064 hasConcept C95444343 @default.
- W4225015064 hasConceptScore W4225015064C104317684 @default.
- W4225015064 hasConceptScore W4225015064C153911025 @default.
- W4225015064 hasConceptScore W4225015064C181199279 @default.
- W4225015064 hasConceptScore W4225015064C185592680 @default.
- W4225015064 hasConceptScore W4225015064C2775838275 @default.
- W4225015064 hasConceptScore W4225015064C2776151105 @default.
- W4225015064 hasConceptScore W4225015064C2776878037 @default.
- W4225015064 hasConceptScore W4225015064C2777248517 @default.
- W4225015064 hasConceptScore W4225015064C2778004101 @default.
- W4225015064 hasConceptScore W4225015064C2778979269 @default.
- W4225015064 hasConceptScore W4225015064C2780795997 @default.
- W4225015064 hasConceptScore W4225015064C48349386 @default.
- W4225015064 hasConceptScore W4225015064C538909803 @default.
- W4225015064 hasConceptScore W4225015064C55493867 @default.