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- W4225101008 abstract "A 39-year-old woman with a history of Alport syndrome was admitted to our hospital for heart failure due to severe aortic regurgitation. Computed tomography revealed a chronic type A aortic dissection that required valve-sparing aortic root replacement. The pathological examination demonstrated that elastic fibers in the tunica media of the aortic wall are torn and severely disorganized. Immunostaining showed fragmented alpha 5 chains, indicating Alport syndrome. These findings imply Alport syndrome may have connective tissue vulnerability, rendering patients susceptible to the development of aortic disease at a young age." @default.
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- W4225101008 date "2022-04-09" @default.
- W4225101008 modified "2023-10-17" @default.
- W4225101008 title "Alport syndrome: A case study of chronic type A aortic dissection" @default.
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- W4225101008 doi "https://doi.org/10.1111/jocs.16496" @default.
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