FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4225117590> ?p ?o ?g. }

• W4225117590 endingPage "e37377" @default.
• W4225117590 startingPage "e37377" @default.
• W4225117590 abstract "The Omicron variant of SARS-CoV-2 is more transmissible than prior variants of concern (VOCs). It has caused the largest outbreaks in the pandemic, with increases in mortality and hospitalizations. Early data on the spread of Omicron were captured in countries with relatively low case counts, so it was unclear how the arrival of Omicron would impact the trajectory of the pandemic in countries already experiencing high levels of community transmission of Delta.The objective of this study is to quantify and explain the impact of Omicron on pandemic trajectories and how they differ between countries that were or were not in a Delta outbreak at the time Omicron occurred.We used SARS-CoV-2 surveillance and genetic sequence data to classify countries into 2 groups: those that were in a Delta outbreak (defined by at least 10 novel daily transmissions per 100,000 population) when Omicron was first sequenced in the country and those that were not. We used trend analysis, survival curves, and dynamic panel regression models to compare outbreaks in the 2 groups over the period from November 1, 2021, to February 11, 2022. We summarized the outbreaks in terms of their peak rate of SARS-CoV-2 infections and the duration of time the outbreaks took to reach the peak rate.Countries that were already in an outbreak with predominantly Delta lineages when Omicron arrived took longer to reach their peak rate and saw greater than a twofold increase (2.04) in the average apex of the Omicron outbreak compared to countries that were not yet in an outbreak.These results suggest that high community transmission of Delta at the time of the first detection of Omicron was not protective, but rather preluded larger outbreaks in those countries. Outbreak status may reflect a generally susceptible population, due to overlapping factors, including climate, policy, and individual behavior. In the absence of strong mitigation measures, arrival of a new, more transmissible variant in these countries is therefore more likely to lead to larger outbreaks. Alternately, countries with enhanced surveillance programs and incentives may be more likely to both exist in an outbreak status and detect more cases during an outbreak, resulting in a spurious relationship. Either way, these data argue against herd immunity mitigating future outbreaks with variants that have undergone significant antigenic shifts." @default.
• W4225117590 created "2022-05-01" @default.
• W4225117590 creator A5004620673 @default.
• W4225117590 creator A5009100986 @default.
• W4225117590 creator A5009813502 @default.
• W4225117590 creator A5011685760 @default.
• W4225117590 creator A5019405556 @default.
• W4225117590 creator A5020247610 @default.
• W4225117590 creator A5024981232 @default.
• W4225117590 creator A5041036157 @default.
• W4225117590 creator A5050045466 @default.
• W4225117590 creator A5063382027 @default.
• W4225117590 creator A5067644316 @default.
• W4225117590 creator A5069518342 @default.
• W4225117590 creator A5076943224 @default.
• W4225117590 date "2022-06-03" @default.
• W4225117590 modified "2023-10-17" @default.
• W4225117590 title "Overlapping Delta and Omicron Outbreaks During the COVID-19 Pandemic: Dynamic Panel Data Estimates" @default.
• W4225117590 cites W1950629566 @default.
• W4225117590 cites W2025610165 @default.
• W4225117590 cites W2027382631 @default.
• W4225117590 cites W2137960802 @default.
• W4225117590 cites W2148974484 @default.
• W4225117590 cites W2408017125 @default.
• W4225117590 cites W2603020828 @default.
• W4225117590 cites W2610297457 @default.
• W4225117590 cites W2793350103 @default.
• W4225117590 cites W2804332183 @default.
• W4225117590 cites W3043124965 @default.
• W4225117590 cites W3084060850 @default.
• W4225117590 cites W3084806672 @default.
• W4225117590 cites W3087558377 @default.
• W4225117590 cites W3090021091 @default.
• W4225117590 cites W3094481451 @default.
• W4225117590 cites W3095922626 @default.
• W4225117590 cites W3100681411 @default.
• W4225117590 cites W3106386073 @default.
• W4225117590 cites W3109205774 @default.
• W4225117590 cites W3112988635 @default.
• W4225117590 cites W3118497926 @default.
• W4225117590 cites W3121658058 @default.
• W4225117590 cites W3123739522 @default.
• W4225117590 cites W3126004755 @default.
• W4225117590 cites W3126027997 @default.
• W4225117590 cites W3134496002 @default.
• W4225117590 cites W3134540911 @default.
• W4225117590 cites W3135257712 @default.
• W4225117590 cites W3151261432 @default.
• W4225117590 cites W3155602756 @default.
• W4225117590 cites W3159771495 @default.
• W4225117590 cites W3164370384 @default.
• W4225117590 cites W3165441111 @default.
• W4225117590 cites W3165870311 @default.
• W4225117590 cites W3180301457 @default.
• W4225117590 cites W3205830567 @default.
• W4225117590 cites W3212439952 @default.
• W4225117590 cites W3212642323 @default.
• W4225117590 cites W4200066927 @default.
• W4225117590 cites W4200094261 @default.
• W4225117590 cites W4200119705 @default.
• W4225117590 cites W4200121261 @default.
• W4225117590 cites W4200170989 @default.
• W4225117590 cites W4200192318 @default.
• W4225117590 cites W4200230275 @default.
• W4225117590 cites W4200247320 @default.
• W4225117590 cites W4200253206 @default.
• W4225117590 cites W4200311999 @default.
• W4225117590 cites W4200340523 @default.
• W4225117590 cites W4200350227 @default.
• W4225117590 cites W4200391585 @default.
• W4225117590 cites W4200427880 @default.
• W4225117590 cites W4200487801 @default.
• W4225117590 cites W4200553670 @default.
• W4225117590 cites W4200565171 @default.
• W4225117590 cites W4200604575 @default.
• W4225117590 cites W4200619717 @default.
• W4225117590 cites W4205703676 @default.
• W4225117590 cites W4206040938 @default.
• W4225117590 cites W4206547321 @default.
• W4225117590 cites W4206675538 @default.
• W4225117590 cites W4206976973 @default.
• W4225117590 cites W4206979529 @default.
• W4225117590 cites W4220673385 @default.
• W4225117590 cites W4220897589 @default.
• W4225117590 cites W4220987557 @default.
• W4225117590 cites W4224950216 @default.
• W4225117590 cites W4225386205 @default.
• W4225117590 cites W4225691034 @default.
• W4225117590 cites W4226050536 @default.
• W4225117590 cites W4226087845 @default.
• W4225117590 cites W4226192094 @default.
• W4225117590 cites W4226229183 @default.
• W4225117590 cites W4226443227 @default.
• W4225117590 doi "https://doi.org/10.2196/37377" @default.
• W4225117590 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35500140" @default.
• W4225117590 hasPublicationYear "2022" @default.
• W4225117590 type Work @default.
• W4225117590 citedByCount "2" @default.

• next