FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4225127890> ?p ?o ?g. }

• W4225127890 endingPage "785" @default.
• W4225127890 startingPage "777" @default.
• W4225127890 abstract "Abstract Aims To conduct a health economic evaluation of ticagrelor in patients with type 2 diabetes and coronary artery disease (CAD) from a multinational payer perspective. Cost–effectiveness and cost–utility of ticagrelor were evaluated in the overall effect of Ticagrelor on Health Outcomes in Diabetes Mellitus Patients Intervention Study (THEMIS) trial population and in the predefined patient group with prior percutaneous coronary intervention. Methods and results A Markov model was developed to extrapolate patient outcomes over a lifetime horizon. The primary outcome was incremental cost–effectiveness ratios (ICERs), which were compared with conventional willingness-to-pay thresholds [€47 000/quality-adjusted life-year (QALY) in Sweden and €30 000/QALY in other countries]. Treatment with ticagrelor resulted in QALY gains of up to 0.045 in the overall population and 0.099 in patients with percutaneous coronary intervention (PCI). Increased costs and benefits translated to ICERs ranged between €27 894 and €42 252/QALY across Sweden, Germany, Italy, and Spain in the overall population. In patients with prior PCI, estimated ICERs improved to €18 449, €20 632, €20 233, and €13 228/QALY in Sweden, Germany, Italy, and Spain, respectively, driven by higher event rates and treatment benefit. Conclusion Based on THEMIS results, ticagrelor plus aspirin compared with aspirin alone may be cost–effective in some European countries in patients with T2DM and CAD and no prior myocardial infarction (MI) or stroke. Additionally, ticagrelor is likely to be cost–effective across European countries in patients with a history of PCI." @default.
• W4225127890 created "2022-05-01" @default.
• W4225127890 creator A5001686107 @default.
• W4225127890 creator A5003831287 @default.
• W4225127890 creator A5007737202 @default.
• W4225127890 creator A5010571732 @default.
• W4225127890 creator A5017448186 @default.
• W4225127890 creator A5035700447 @default.
• W4225127890 creator A5040754419 @default.
• W4225127890 creator A5044052327 @default.
• W4225127890 creator A5051592573 @default.
• W4225127890 creator A5053660748 @default.
• W4225127890 creator A5057167171 @default.
• W4225127890 creator A5058098020 @default.
• W4225127890 creator A5060370891 @default.
• W4225127890 creator A5068562796 @default.
• W4225127890 creator A5073596004 @default.
• W4225127890 creator A5074572540 @default.
• W4225127890 creator A5080414941 @default.
• W4225127890 creator A5090902821 @default.
• W4225127890 date "2022-04-30" @default.
• W4225127890 modified "2023-09-30" @default.
• W4225127890 title "Cost–effectiveness of ticagrelor in patients with type 2 diabetes and coronary artery disease: a European economic evaluation of the THEMIS trial" @default.
• W4225127890 cites W2002189205 @default.
• W4225127890 cites W2013564592 @default.
• W4225127890 cites W2040816046 @default.
• W4225127890 cites W2051424809 @default.
• W4225127890 cites W2070327180 @default.
• W4225127890 cites W2078317138 @default.
• W4225127890 cites W2110544662 @default.
• W4225127890 cites W2122779695 @default.
• W4225127890 cites W2130827378 @default.
• W4225127890 cites W2142164422 @default.
• W4225127890 cites W2147663252 @default.
• W4225127890 cites W2154038775 @default.
• W4225127890 cites W2501112626 @default.
• W4225127890 cites W2579918811 @default.
• W4225127890 cites W2752189600 @default.
• W4225127890 cites W2772302443 @default.
• W4225127890 cites W2788008365 @default.
• W4225127890 cites W2796182819 @default.
• W4225127890 cites W2806521060 @default.
• W4225127890 cites W2809463321 @default.
• W4225127890 cites W2917620857 @default.
• W4225127890 cites W2927831437 @default.
• W4225127890 cites W2970797239 @default.
• W4225127890 cites W2971019453 @default.
• W4225127890 cites W2981412695 @default.
• W4225127890 cites W2982380086 @default.
• W4225127890 cites W3016566219 @default.
• W4225127890 cites W3162843285 @default.
• W4225127890 cites W3193919932 @default.
• W4225127890 cites W4226272138 @default.
• W4225127890 cites W591057956 @default.
• W4225127890 doi "https://doi.org/10.1093/ehjcvp/pvac032" @default.
• W4225127890 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35488865" @default.
• W4225127890 hasPublicationYear "2022" @default.
• W4225127890 type Work @default.
• W4225127890 citedByCount "3" @default.
• W4225127890 countsByYear W42251278902022 @default.
• W4225127890 countsByYear W42251278902023 @default.
• W4225127890 crossrefType "journal-article" @default.
• W4225127890 hasAuthorship W4225127890A5001686107 @default.
• W4225127890 hasAuthorship W4225127890A5003831287 @default.
• W4225127890 hasAuthorship W4225127890A5007737202 @default.
• W4225127890 hasAuthorship W4225127890A5010571732 @default.
• W4225127890 hasAuthorship W4225127890A5017448186 @default.
• W4225127890 hasAuthorship W4225127890A5035700447 @default.
• W4225127890 hasAuthorship W4225127890A5040754419 @default.
• W4225127890 hasAuthorship W4225127890A5044052327 @default.
• W4225127890 hasAuthorship W4225127890A5051592573 @default.
• W4225127890 hasAuthorship W4225127890A5053660748 @default.
• W4225127890 hasAuthorship W4225127890A5057167171 @default.
• W4225127890 hasAuthorship W4225127890A5058098020 @default.
• W4225127890 hasAuthorship W4225127890A5060370891 @default.
• W4225127890 hasAuthorship W4225127890A5068562796 @default.
• W4225127890 hasAuthorship W4225127890A5073596004 @default.
• W4225127890 hasAuthorship W4225127890A5074572540 @default.
• W4225127890 hasAuthorship W4225127890A5080414941 @default.
• W4225127890 hasAuthorship W4225127890A5090902821 @default.
• W4225127890 hasBestOaLocation W42251278901 @default.
• W4225127890 hasConcept C112930515 @default.
• W4225127890 hasConcept C126322002 @default.
• W4225127890 hasConcept C127413603 @default.
• W4225127890 hasConcept C2777628954 @default.
• W4225127890 hasConcept C2778213512 @default.
• W4225127890 hasConcept C2780400711 @default.
• W4225127890 hasConcept C2780645631 @default.
• W4225127890 hasConcept C2780890252 @default.
• W4225127890 hasConcept C2908647359 @default.
• W4225127890 hasConcept C3019080777 @default.
• W4225127890 hasConcept C45393284 @default.
• W4225127890 hasConcept C500558357 @default.
• W4225127890 hasConcept C64332521 @default.
• W4225127890 hasConcept C71924100 @default.
• W4225127890 hasConcept C78519656 @default.
• W4225127890 hasConcept C99454951 @default.
• W4225127890 hasConceptScore W4225127890C112930515 @default.

• next