FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4225157024> ?p ?o ?g. }

• W4225157024 abstract "This study aimed to noninvasively predict the mutation status of epidermal growth factor receptor (EGFR) molecular subtype in lung adenocarcinoma based on CT radiomics features.In total, 728 patients with lung adenocarcinoma were included, and divided into three groups according to EGFR mutation subtypes. 1727 radiomics features were extracted from the three-dimensional images of each patient. Wilcoxon test, least absolute shrinkage and selection operator regression, and multiple logistic regression were used for feature selection. ROC curve was used to evaluate the predictive performance of the model. Nomogram was constructed by combining radiomics features and clinical risk factors. Calibration curve was used to evaluate the goodness of fit of the model. Decision curve analysis was used to evaluate the clinical applicability of the model.There were three, two, and one clinical factor and fourteen, thirteen, and four radiomics features, respectively, which were significantly related to each EGFR molecular subtype. Compared with the clinical and radiomics models, the combined model had the highest predictive performance in predicting EGFR molecular subtypes [Del-19 mutation vs. wild-type, AUC=0.838 (95% CI, 0.799-0.877); L858R mutation vs. wild-type, AUC=0.855 (95% CI, 0.817-0.894); and Del-19 mutation vs. L858R mutation, AUC=0.906 (95% CI, 0.869-0.943), respectively], and it has a stable performance in the validation set [AUC was 0.813 (95% CI, 0.740-0.886), 0.852 (95% CI, 0.790-0.913), and 0.875 (95% CI, 0.781-0.929), respectively].Our combined model showed good performance in predicting EGFR molecular subtypes in patients with lung adenocarcinoma. This model can be applied to patients with lung adenocarcinoma." @default.
• W4225157024 created "2022-05-01" @default.
• W4225157024 creator A5001030035 @default.
• W4225157024 creator A5001928494 @default.
• W4225157024 creator A5011864143 @default.
• W4225157024 creator A5017947172 @default.
• W4225157024 creator A5023419739 @default.
• W4225157024 creator A5033298072 @default.
• W4225157024 creator A5035832774 @default.
• W4225157024 creator A5040682167 @default.
• W4225157024 creator A5046777459 @default.
• W4225157024 creator A5058246931 @default.
• W4225157024 creator A5058668034 @default.
• W4225157024 creator A5060788268 @default.
• W4225157024 creator A5088960713 @default.
• W4225157024 date "2022-04-29" @default.
• W4225157024 modified "2023-10-16" @default.
• W4225157024 title "Development of a Nomogram Based on 3D CT Radiomics Signature to Predict the Mutation Status of EGFR Molecular Subtypes in Lung Adenocarcinoma: A Multicenter Study" @default.
• W4225157024 cites W2000785208 @default.
• W4225157024 cites W2076178766 @default.
• W4225157024 cites W2101569260 @default.
• W4225157024 cites W2129590156 @default.
• W4225157024 cites W2140124489 @default.
• W4225157024 cites W2174661749 @default.
• W4225157024 cites W2287231805 @default.
• W4225157024 cites W2290433232 @default.
• W4225157024 cites W2461805626 @default.
• W4225157024 cites W2560717039 @default.
• W4225157024 cites W2584153090 @default.
• W4225157024 cites W2770828094 @default.
• W4225157024 cites W2775847164 @default.
• W4225157024 cites W2790185976 @default.
• W4225157024 cites W2806325305 @default.
• W4225157024 cites W2807519281 @default.
• W4225157024 cites W2896617188 @default.
• W4225157024 cites W2903686982 @default.
• W4225157024 cites W2915540738 @default.
• W4225157024 cites W2923148806 @default.
• W4225157024 cites W2926971658 @default.
• W4225157024 cites W2953404953 @default.
• W4225157024 cites W2966334392 @default.
• W4225157024 cites W2976516489 @default.
• W4225157024 cites W2990041408 @default.
• W4225157024 cites W2990087304 @default.
• W4225157024 cites W2998789541 @default.
• W4225157024 cites W2999691771 @default.
• W4225157024 cites W3003975456 @default.
• W4225157024 cites W3037626323 @default.
• W4225157024 cites W3045506849 @default.
• W4225157024 cites W3046420495 @default.
• W4225157024 cites W3088644716 @default.
• W4225157024 cites W3107758137 @default.
• W4225157024 cites W3138402016 @default.
• W4225157024 doi "https://doi.org/10.3389/fonc.2022.889293" @default.
• W4225157024 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35574401" @default.
• W4225157024 hasPublicationYear "2022" @default.
• W4225157024 type Work @default.
• W4225157024 citedByCount "2" @default.
• W4225157024 countsByYear W42251570242022 @default.
• W4225157024 countsByYear W42251570242023 @default.
• W4225157024 crossrefType "journal-article" @default.
• W4225157024 hasAuthorship W4225157024A5001030035 @default.
• W4225157024 hasAuthorship W4225157024A5001928494 @default.
• W4225157024 hasAuthorship W4225157024A5011864143 @default.
• W4225157024 hasAuthorship W4225157024A5017947172 @default.
• W4225157024 hasAuthorship W4225157024A5023419739 @default.
• W4225157024 hasAuthorship W4225157024A5033298072 @default.
• W4225157024 hasAuthorship W4225157024A5035832774 @default.
• W4225157024 hasAuthorship W4225157024A5040682167 @default.
• W4225157024 hasAuthorship W4225157024A5046777459 @default.
• W4225157024 hasAuthorship W4225157024A5058246931 @default.
• W4225157024 hasAuthorship W4225157024A5058668034 @default.
• W4225157024 hasAuthorship W4225157024A5060788268 @default.
• W4225157024 hasAuthorship W4225157024A5088960713 @default.
• W4225157024 hasBestOaLocation W42251570241 @default.
• W4225157024 hasConcept C104317684 @default.
• W4225157024 hasConcept C121608353 @default.
• W4225157024 hasConcept C126322002 @default.
• W4225157024 hasConcept C126838900 @default.
• W4225157024 hasConcept C142724271 @default.
• W4225157024 hasConcept C143998085 @default.
• W4225157024 hasConcept C151956035 @default.
• W4225157024 hasConcept C2778559731 @default.
• W4225157024 hasConcept C2781182431 @default.
• W4225157024 hasConcept C34626388 @default.
• W4225157024 hasConcept C501734568 @default.
• W4225157024 hasConcept C54355233 @default.
• W4225157024 hasConcept C58471807 @default.
• W4225157024 hasConcept C71924100 @default.
• W4225157024 hasConcept C76318530 @default.
• W4225157024 hasConcept C86803240 @default.
• W4225157024 hasConceptScore W4225157024C104317684 @default.
• W4225157024 hasConceptScore W4225157024C121608353 @default.
• W4225157024 hasConceptScore W4225157024C126322002 @default.
• W4225157024 hasConceptScore W4225157024C126838900 @default.
• W4225157024 hasConceptScore W4225157024C142724271 @default.
• W4225157024 hasConceptScore W4225157024C143998085 @default.
• W4225157024 hasConceptScore W4225157024C151956035 @default.
• W4225157024 hasConceptScore W4225157024C2778559731 @default.
• W4225157024 hasConceptScore W4225157024C2781182431 @default.

• next