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- W4225159517 abstract "Emerging evidence suggests that, along with dietary, genetic and environmental factors, gut microbiota plays a role in the progress of colorectal cancer. Dysbiosis of oral flora in patients with periodontitis affects the composition of microbial community in the gut, impairs gut barrier function, and induces a proinflammatory microenvironment, all of which contribute to the progression of colorectal cancer. In view of the influences by microbiota dysbiosis, this article reviews the role of periodontitis in affecting the occurrence and development of colorectal cancer.结直肠癌是一种常见的恶性肿瘤，其发生发展受饮食、遗传、环境和代谢等多种因素的影响。肠道微生物组成的变化是重要的内部环境之一，与结直肠癌的发生发展密切相关。而牙周炎患者的口腔菌群失调可影响肠道菌群的组成，降低肠道的屏障功能，促进炎症微环境的形成，进而促进结直肠癌的进展。本文从菌群失调入手，对牙周炎促进结直肠癌发生发展的作用进行综述。." @default.
- W4225159517 created "2022-05-01" @default.
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- W4225159517 date "2022-05-09" @default.
- W4225159517 modified "2023-10-16" @default.
- W4225159517 title "[Can periodontitis affect colorectal cancer by altering microbiota balance?]" @default.
- W4225159517 doi "https://doi.org/10.3760/cma.j.cn112144-20220303-00090" @default.
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