Matches in SemOpenAlex for { <https://semopenalex.org/work/W4225276543> ?p ?o ?g. }
Showing items 1 to 64 of
64
with 100 items per page.
- W4225276543 endingPage "e2" @default.
- W4225276543 startingPage "e1" @default.
- W4225276543 abstract "A 43-year-old woman diagnosed with granular corneal dystrophy (GCD) type 2 on the basis of bilateral granular deposition in the corneal stroma (Fig. 1A) and the detection of a heterozygous R124H mutation of the transforming growth factor–β–induced gene (TGFIB) presented with ocular pain and conjunctival hyperemia in her left eye. Slitlamp examination showed swelling and congestion of the left conjunctiva associated with yellowish-white deposits in the bulbar region (Fig. 1B). Two weeks later, similar conjunctival lesions appeared in the lower portion of her right eye. Biopsy and histopathologic examination of the left conjunctival lesions revealed eosinophilic deposits in the lamina propria (Fig. 1C). The conjunctival deposits reacted with Masson's trichrome stain (Fig. 1D) and Luxol fast blue but not with Congo red, suggesting the presence of hyaline but not amyloid. Treatment with betamethasone eyedrops attenuated the redness and swelling of the conjunctiva as well as induced regression of the protrusions in both eyes. Hyalin bodies are occasionally observed in the superficial layers of the conjunctival epithelium in the elderly, but not in patients younger than 79 years. Our case is very unusual because of the patient's young age and the hyaline depositing mass in the conjunctival stroma. The corneal deposits of GCD type 2 have been shown to be composed of hyaline and amyloid. This is the first reported case of GCD type 2 associated with hyaline deposition in a tissue other than the cornea." @default.
- W4225276543 created "2022-05-04" @default.
- W4225276543 creator A5028575367 @default.
- W4225276543 creator A5045602197 @default.
- W4225276543 creator A5053130083 @default.
- W4225276543 creator A5059355075 @default.
- W4225276543 creator A5082408504 @default.
- W4225276543 creator A5086028584 @default.
- W4225276543 date "2022-08-01" @default.
- W4225276543 modified "2023-10-12" @default.
- W4225276543 title "Atypical conjunctival hyaline deposition in a case of granular corneal dystrophy type 2" @default.
- W4225276543 doi "https://doi.org/10.1016/j.ajo.2022.04.012" @default.
- W4225276543 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35513029" @default.
- W4225276543 hasPublicationYear "2022" @default.
- W4225276543 type Work @default.
- W4225276543 citedByCount "0" @default.
- W4225276543 crossrefType "journal-article" @default.
- W4225276543 hasAuthorship W4225276543A5028575367 @default.
- W4225276543 hasAuthorship W4225276543A5045602197 @default.
- W4225276543 hasAuthorship W4225276543A5053130083 @default.
- W4225276543 hasAuthorship W4225276543A5059355075 @default.
- W4225276543 hasAuthorship W4225276543A5082408504 @default.
- W4225276543 hasAuthorship W4225276543A5086028584 @default.
- W4225276543 hasBestOaLocation W42252765431 @default.
- W4225276543 hasConcept C105702510 @default.
- W4225276543 hasConcept C118487528 @default.
- W4225276543 hasConcept C118494813 @default.
- W4225276543 hasConcept C142724271 @default.
- W4225276543 hasConcept C163031210 @default.
- W4225276543 hasConcept C204232928 @default.
- W4225276543 hasConcept C2775984611 @default.
- W4225276543 hasConcept C2776882836 @default.
- W4225276543 hasConcept C52124034 @default.
- W4225276543 hasConcept C71924100 @default.
- W4225276543 hasConceptScore W4225276543C105702510 @default.
- W4225276543 hasConceptScore W4225276543C118487528 @default.
- W4225276543 hasConceptScore W4225276543C118494813 @default.
- W4225276543 hasConceptScore W4225276543C142724271 @default.
- W4225276543 hasConceptScore W4225276543C163031210 @default.
- W4225276543 hasConceptScore W4225276543C204232928 @default.
- W4225276543 hasConceptScore W4225276543C2775984611 @default.
- W4225276543 hasConceptScore W4225276543C2776882836 @default.
- W4225276543 hasConceptScore W4225276543C52124034 @default.
- W4225276543 hasConceptScore W4225276543C71924100 @default.
- W4225276543 hasLocation W42252765431 @default.
- W4225276543 hasLocation W42252765432 @default.
- W4225276543 hasOpenAccess W4225276543 @default.
- W4225276543 hasPrimaryLocation W42252765431 @default.
- W4225276543 hasRelatedWork W184757023 @default.
- W4225276543 hasRelatedWork W1977439500 @default.
- W4225276543 hasRelatedWork W1996853317 @default.
- W4225276543 hasRelatedWork W2010062690 @default.
- W4225276543 hasRelatedWork W2187707974 @default.
- W4225276543 hasRelatedWork W2397360123 @default.
- W4225276543 hasRelatedWork W2987802902 @default.
- W4225276543 hasRelatedWork W35495171 @default.
- W4225276543 hasRelatedWork W4286835824 @default.
- W4225276543 hasRelatedWork W85560277 @default.
- W4225276543 hasVolume "240" @default.
- W4225276543 isParatext "false" @default.
- W4225276543 isRetracted "false" @default.
- W4225276543 workType "article" @default.