Matches in SemOpenAlex for { <https://semopenalex.org/work/W4225278620> ?p ?o ?g. }
- W4225278620 endingPage "120996" @default.
- W4225278620 startingPage "120996" @default.
- W4225278620 abstract "Antibiotic resistance is one of the world’s most urgent healthcare challenges. Antimicrobial photodynamic therapy (aPDT) has shown promise in combating this growing threat. In aPDT, photoactivation of a sensitizer leads to the generation of reactive oxygen species, which induces bacterial cell death by damaging vital biomolecules. Ruthenium polypyridyl complexes possess rich photophysical properties and have been shown to generate singlet oxygen species upon light activation. Herein, we report antibacterial photodynamic properties of ruthenium (II) polypyridyl complex, [RuCl(MePhtpy)(dpp)]+ (where, MePhtpy = 4′-(4-methylphenyl)-2,2′:6′,2′'-terpyridine and dpp = 2,3-bis(2-pyridyl)pyrazine). The complex displays antibacterial properties in the absence of light, which are further enhanced upon photoirradiation. Agarose gel electrophoresis studies on DNA extracted from treated bacterial cells revealed that binding to DNA is not responsible for these antimicrobial photodynamic properties and that further studies are needed to identify the target biomolecule(s) of [RuCl(MePhtpy)(dpp)](PF6)." @default.
- W4225278620 created "2022-05-04" @default.
- W4225278620 creator A5064270682 @default.
- W4225278620 creator A5065284710 @default.
- W4225278620 creator A5085881029 @default.
- W4225278620 date "2022-08-01" @default.
- W4225278620 modified "2023-10-14" @default.
- W4225278620 title "Photodynamic antimicrobial studies on a Ruthenium-based metal complex" @default.
- W4225278620 cites W1978716231 @default.
- W4225278620 cites W1982298817 @default.
- W4225278620 cites W1994426246 @default.
- W4225278620 cites W1998297675 @default.
- W4225278620 cites W2002306693 @default.
- W4225278620 cites W2002380846 @default.
- W4225278620 cites W2019098068 @default.
- W4225278620 cites W2023460725 @default.
- W4225278620 cites W2024437480 @default.
- W4225278620 cites W2042062103 @default.
- W4225278620 cites W2042246520 @default.
- W4225278620 cites W2046624268 @default.
- W4225278620 cites W2050430738 @default.
- W4225278620 cites W2055915619 @default.
- W4225278620 cites W2087152379 @default.
- W4225278620 cites W2100591192 @default.
- W4225278620 cites W2104126843 @default.
- W4225278620 cites W2110193006 @default.
- W4225278620 cites W2137854825 @default.
- W4225278620 cites W2138433877 @default.
- W4225278620 cites W2149944391 @default.
- W4225278620 cites W2152137749 @default.
- W4225278620 cites W2278726896 @default.
- W4225278620 cites W2332843627 @default.
- W4225278620 cites W2393563438 @default.
- W4225278620 cites W2407305065 @default.
- W4225278620 cites W2410429991 @default.
- W4225278620 cites W2511874499 @default.
- W4225278620 cites W2516910933 @default.
- W4225278620 cites W2549136394 @default.
- W4225278620 cites W2580702166 @default.
- W4225278620 cites W2592308048 @default.
- W4225278620 cites W2622062417 @default.
- W4225278620 cites W2736390504 @default.
- W4225278620 cites W2772136362 @default.
- W4225278620 cites W2774290463 @default.
- W4225278620 cites W2782716004 @default.
- W4225278620 cites W2800147280 @default.
- W4225278620 cites W2806673097 @default.
- W4225278620 cites W2887652955 @default.
- W4225278620 cites W2889119483 @default.
- W4225278620 cites W2891810428 @default.
- W4225278620 cites W2911578653 @default.
- W4225278620 cites W2955358713 @default.
- W4225278620 cites W2970628411 @default.
- W4225278620 cites W2992113953 @default.
- W4225278620 cites W2992694119 @default.
- W4225278620 cites W2995541140 @default.
- W4225278620 cites W2996030696 @default.
- W4225278620 cites W3005921653 @default.
- W4225278620 cites W3039308761 @default.
- W4225278620 cites W3090627291 @default.
- W4225278620 cites W3090999060 @default.
- W4225278620 cites W3093217897 @default.
- W4225278620 cites W3163210487 @default.
- W4225278620 cites W4211057422 @default.
- W4225278620 doi "https://doi.org/10.1016/j.ica.2022.120996" @default.
- W4225278620 hasPublicationYear "2022" @default.
- W4225278620 type Work @default.
- W4225278620 citedByCount "3" @default.
- W4225278620 countsByYear W42252786202022 @default.
- W4225278620 countsByYear W42252786202023 @default.
- W4225278620 crossrefType "journal-article" @default.
- W4225278620 hasAuthorship W4225278620A5064270682 @default.
- W4225278620 hasAuthorship W4225278620A5065284710 @default.
- W4225278620 hasAuthorship W4225278620A5085881029 @default.
- W4225278620 hasConcept C161790260 @default.
- W4225278620 hasConcept C178790620 @default.
- W4225278620 hasConcept C185592680 @default.
- W4225278620 hasConcept C21951064 @default.
- W4225278620 hasConcept C2777516457 @default.
- W4225278620 hasConcept C2778271344 @default.
- W4225278620 hasConcept C2780104969 @default.
- W4225278620 hasConcept C2781323092 @default.
- W4225278620 hasConcept C2781350956 @default.
- W4225278620 hasConcept C48349386 @default.
- W4225278620 hasConcept C4937899 @default.
- W4225278620 hasConcept C49853544 @default.
- W4225278620 hasConcept C523546767 @default.
- W4225278620 hasConcept C540031477 @default.
- W4225278620 hasConcept C54355233 @default.
- W4225278620 hasConcept C544153396 @default.
- W4225278620 hasConcept C552990157 @default.
- W4225278620 hasConcept C55493867 @default.
- W4225278620 hasConcept C555196967 @default.
- W4225278620 hasConcept C75473681 @default.
- W4225278620 hasConcept C86803240 @default.
- W4225278620 hasConceptScore W4225278620C161790260 @default.
- W4225278620 hasConceptScore W4225278620C178790620 @default.
- W4225278620 hasConceptScore W4225278620C185592680 @default.