FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4225287512> ?p ?o ?g. }

• W4225287512 endingPage "1816" @default.
• W4225287512 startingPage "1816" @default.
• W4225287512 abstract "During wound healing, bacterial infection is one of the main limiting factors for the desired efficiency. Wound dressing-mediated antibiotics therapies could overcome this problem to a great extent due to sustained drug release and controllable dose. Here, we designed a kind of alginate injectable hydrogel loaded with minocycline (SA@MC) as a dressing for staphylococcus aureus-infected wound healing. SA@MC hydrogel possessed good injectability and can be injected by syringes. MC participated in the gel formation, causing the microstructure change based on the morphology characterization. The element mapping and FT-IR spectra further confirmed the successful loading of MC in SA hydrogel. Interestingly, MC was released more efficiently in a weakly alkaline condition (pH 7–8) than in a weakly acidic condition (pH 4–6) from SA@MC injectable hydrogel, which means that there is an accelerated release to respond to the weakly alkaline wound microenvironment. Meanwhile, SA@MC injectable hydrogel had high biocompatibility and excellent antibacterial activity due to the sustained release of MC. Further, in vivo experiment results demonstrated that SA@MC injectable hydrogel promoted staphylococcus aureus-infected wound healing efficiently. In summary, the injectable composite hydrogel can serve as an ideal dressing to prevent bacterial infection and promote wound healing." @default.
• W4225287512 created "2022-05-05" @default.
• W4225287512 creator A5012349246 @default.
• W4225287512 creator A5013451791 @default.
• W4225287512 creator A5028490219 @default.
• W4225287512 creator A5061633389 @default.
• W4225287512 creator A5082357190 @default.
• W4225287512 date "2022-04-29" @default.
• W4225287512 modified "2023-10-14" @default.
• W4225287512 title "Sustained and Microenvironment-Accelerated Release of Minocycline from Alginate Injectable Hydrogel for Bacteria-Infected Wound Healing" @default.
• W4225287512 cites W1992407852 @default.
• W4225287512 cites W1999271022 @default.
• W4225287512 cites W2001447678 @default.
• W4225287512 cites W2056206021 @default.
• W4225287512 cites W2332968100 @default.
• W4225287512 cites W2345853376 @default.
• W4225287512 cites W2507439294 @default.
• W4225287512 cites W2579302807 @default.
• W4225287512 cites W2787874969 @default.
• W4225287512 cites W2794279282 @default.
• W4225287512 cites W2909505539 @default.
• W4225287512 cites W2910956760 @default.
• W4225287512 cites W2916903224 @default.
• W4225287512 cites W2968947248 @default.
• W4225287512 cites W3002076090 @default.
• W4225287512 cites W3003924126 @default.
• W4225287512 cites W3033134281 @default.
• W4225287512 cites W3105255083 @default.
• W4225287512 cites W3127828393 @default.
• W4225287512 cites W3137746295 @default.
• W4225287512 cites W3151198666 @default.
• W4225287512 cites W3173420867 @default.
• W4225287512 cites W3191069748 @default.
• W4225287512 cites W3193219480 @default.
• W4225287512 cites W3210457093 @default.
• W4225287512 cites W4221067010 @default.
• W4225287512 cites W4248304441 @default.
• W4225287512 doi "https://doi.org/10.3390/polym14091816" @default.
• W4225287512 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35566985" @default.
• W4225287512 hasPublicationYear "2022" @default.
• W4225287512 type Work @default.
• W4225287512 citedByCount "7" @default.
• W4225287512 countsByYear W42252875122022 @default.
• W4225287512 countsByYear W42252875122023 @default.
• W4225287512 crossrefType "journal-article" @default.
• W4225287512 hasAuthorship W4225287512A5012349246 @default.
• W4225287512 hasAuthorship W4225287512A5013451791 @default.
• W4225287512 hasAuthorship W4225287512A5028490219 @default.
• W4225287512 hasAuthorship W4225287512A5061633389 @default.
• W4225287512 hasAuthorship W4225287512A5082357190 @default.
• W4225287512 hasBestOaLocation W42252875121 @default.
• W4225287512 hasConcept C108586683 @default.
• W4225287512 hasConcept C136229726 @default.
• W4225287512 hasConcept C141071460 @default.
• W4225287512 hasConcept C150903083 @default.
• W4225287512 hasConcept C163588942 @default.
• W4225287512 hasConcept C178790620 @default.
• W4225287512 hasConcept C185592680 @default.
• W4225287512 hasConcept C188027245 @default.
• W4225287512 hasConcept C207001950 @default.
• W4225287512 hasConcept C2777230088 @default.
• W4225287512 hasConcept C2778275353 @default.
• W4225287512 hasConcept C2779489039 @default.
• W4225287512 hasConcept C2780269544 @default.
• W4225287512 hasConcept C501593827 @default.
• W4225287512 hasConcept C523546767 @default.
• W4225287512 hasConcept C54355233 @default.
• W4225287512 hasConcept C55493867 @default.
• W4225287512 hasConcept C71924100 @default.
• W4225287512 hasConcept C86803240 @default.
• W4225287512 hasConcept C89423630 @default.
• W4225287512 hasConcept C98274493 @default.
• W4225287512 hasConceptScore W4225287512C108586683 @default.
• W4225287512 hasConceptScore W4225287512C136229726 @default.
• W4225287512 hasConceptScore W4225287512C141071460 @default.
• W4225287512 hasConceptScore W4225287512C150903083 @default.
• W4225287512 hasConceptScore W4225287512C163588942 @default.
• W4225287512 hasConceptScore W4225287512C178790620 @default.
• W4225287512 hasConceptScore W4225287512C185592680 @default.
• W4225287512 hasConceptScore W4225287512C188027245 @default.
• W4225287512 hasConceptScore W4225287512C207001950 @default.
• W4225287512 hasConceptScore W4225287512C2777230088 @default.
• W4225287512 hasConceptScore W4225287512C2778275353 @default.
• W4225287512 hasConceptScore W4225287512C2779489039 @default.
• W4225287512 hasConceptScore W4225287512C2780269544 @default.
• W4225287512 hasConceptScore W4225287512C501593827 @default.
• W4225287512 hasConceptScore W4225287512C523546767 @default.
• W4225287512 hasConceptScore W4225287512C54355233 @default.
• W4225287512 hasConceptScore W4225287512C55493867 @default.
• W4225287512 hasConceptScore W4225287512C71924100 @default.
• W4225287512 hasConceptScore W4225287512C86803240 @default.
• W4225287512 hasConceptScore W4225287512C89423630 @default.
• W4225287512 hasConceptScore W4225287512C98274493 @default.
• W4225287512 hasFunder F4320321001 @default.
• W4225287512 hasFunder F4320324174 @default.
• W4225287512 hasIssue "9" @default.
• W4225287512 hasLocation W42252875121 @default.
• W4225287512 hasLocation W42252875122 @default.

• next