FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4225302781> ?p ?o ?g. }

• W4225302781 abstract "Patients with primary hyperparathyroidism (pHPT) and impaired kidney function (estimated glomerular filtration rate (eGFR) < 60 mL/min) are offered parathyroidectomy (PTX) to protect them from further complications. Surprisingly, two recent uncontrolled cohort studies have suggested a further decrease in kidney function following PTX. We aimed to examine the effects of PTX compared to non-surgical surveillance on kidney function in pHPT patients.Historic cohort study. From the Danish National Patient Registry (NPR) and major medical biochemistry laboratories in Denmark, we identified 3585 patients with biochemically confirmed pHPT among whom n = 1977 (55%) were treated with PTX (PTX-group) whereas n = 1608 (45%) were followed without surgery (non-PTX group). Baseline was defined as time of diagnosis and kidney function was re-assessed 9-15 months after PTX (PTX group) or 9-15 months after diagnosis (non-PTX group).At follow-up, eGFR had decreased significantly in the PTX- compared to the non-PTX-group (median - 4% vs. - 1%, p < 0.01). Stratification by baseline eGFR showed that the decrease was significant for those with a baseline eGFR value of 80-89 and > 90 mL/min, but not for those with lower eGFR values. Findings did not differ between patients with mild compared to moderate/severe hypercalcemia. However, after mutual adjustments, we identified baseline levels of calcium, PTH, and eGFR as well as age and treatment (PTX vs. no-PTX) as independent predictors for changes in kidney function.Compared to non-surgical surveillance, PTX is associated with a small but significant decrease in kidney function in pHPT patients with an initial normal kidney function." @default.
• W4225302781 created "2022-05-05" @default.
• W4225302781 creator A5008946327 @default.
• W4225302781 creator A5032591631 @default.
• W4225302781 creator A5036824028 @default.
• W4225302781 creator A5051386441 @default.
• W4225302781 creator A5061192413 @default.
• W4225302781 creator A5061853414 @default.
• W4225302781 creator A5066576087 @default.
• W4225302781 creator A5067258958 @default.
• W4225302781 creator A5067767608 @default.
• W4225302781 creator A5083801035 @default.
• W4225302781 date "2022-01-06" @default.
• W4225302781 modified "2023-09-26" @default.
• W4225302781 title "The effect of parathyroidectomy compared to non-surgical surveillance on kidney function in primary hyperparathyroidism: a nationwide historic cohort study" @default.
• W4225302781 cites W1916364140 @default.
• W4225302781 cites W1964331231 @default.
• W4225302781 cites W1967945152 @default.
• W4225302781 cites W1983966778 @default.
• W4225302781 cites W1984957306 @default.
• W4225302781 cites W1989554784 @default.
• W4225302781 cites W2006632162 @default.
• W4225302781 cites W2006984304 @default.
• W4225302781 cites W2031862399 @default.
• W4225302781 cites W2035295349 @default.
• W4225302781 cites W2042484533 @default.
• W4225302781 cites W2050301212 @default.
• W4225302781 cites W2051155551 @default.
• W4225302781 cites W2051208577 @default.
• W4225302781 cites W2056833134 @default.
• W4225302781 cites W2059543709 @default.
• W4225302781 cites W2061793431 @default.
• W4225302781 cites W2076927105 @default.
• W4225302781 cites W2079225330 @default.
• W4225302781 cites W2085377174 @default.
• W4225302781 cites W2086695519 @default.
• W4225302781 cites W2087707445 @default.
• W4225302781 cites W2104954752 @default.
• W4225302781 cites W2109509624 @default.
• W4225302781 cites W2114710197 @default.
• W4225302781 cites W2144102059 @default.
• W4225302781 cites W2144495692 @default.
• W4225302781 cites W2146091120 @default.
• W4225302781 cites W2155965977 @default.
• W4225302781 cites W2169367554 @default.
• W4225302781 cites W2219591537 @default.
• W4225302781 cites W2415778807 @default.
• W4225302781 cites W2439014402 @default.
• W4225302781 cites W2515002635 @default.
• W4225302781 cites W2558096072 @default.
• W4225302781 cites W2607031541 @default.
• W4225302781 cites W2751110334 @default.
• W4225302781 cites W2884318746 @default.
• W4225302781 cites W2894074914 @default.
• W4225302781 cites W2900775703 @default.
• W4225302781 cites W2934694044 @default.
• W4225302781 cites W2963159076 @default.
• W4225302781 cites W2991907277 @default.
• W4225302781 cites W3206083345 @default.
• W4225302781 cites W4211028492 @default.
• W4225302781 cites W4230414410 @default.
• W4225302781 cites W4237538204 @default.
• W4225302781 cites W4297914826 @default.
• W4225302781 cites W4376999369 @default.
• W4225302781 doi "https://doi.org/10.1186/s12902-021-00918-z" @default.
• W4225302781 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34991581" @default.
• W4225302781 hasPublicationYear "2022" @default.
• W4225302781 type Work @default.
• W4225302781 citedByCount "2" @default.
• W4225302781 countsByYear W42253027812022 @default.
• W4225302781 countsByYear W42253027812023 @default.
• W4225302781 crossrefType "journal-article" @default.
• W4225302781 hasAuthorship W4225302781A5008946327 @default.
• W4225302781 hasAuthorship W4225302781A5032591631 @default.
• W4225302781 hasAuthorship W4225302781A5036824028 @default.
• W4225302781 hasAuthorship W4225302781A5051386441 @default.
• W4225302781 hasAuthorship W4225302781A5061192413 @default.
• W4225302781 hasAuthorship W4225302781A5061853414 @default.
• W4225302781 hasAuthorship W4225302781A5066576087 @default.
• W4225302781 hasAuthorship W4225302781A5067258958 @default.
• W4225302781 hasAuthorship W4225302781A5067767608 @default.
• W4225302781 hasAuthorship W4225302781A5083801035 @default.
• W4225302781 hasBestOaLocation W42253027811 @default.
• W4225302781 hasConcept C126322002 @default.
• W4225302781 hasConcept C126894567 @default.
• W4225302781 hasConcept C134018914 @default.
• W4225302781 hasConcept C159641895 @default.
• W4225302781 hasConcept C2777645128 @default.
• W4225302781 hasConcept C2779053571 @default.
• W4225302781 hasConcept C2780091579 @default.
• W4225302781 hasConcept C2781208988 @default.
• W4225302781 hasConcept C519063684 @default.
• W4225302781 hasConcept C71924100 @default.
• W4225302781 hasConcept C72563966 @default.
• W4225302781 hasConcept C90924648 @default.
• W4225302781 hasConceptScore W4225302781C126322002 @default.
• W4225302781 hasConceptScore W4225302781C126894567 @default.
• W4225302781 hasConceptScore W4225302781C134018914 @default.
• W4225302781 hasConceptScore W4225302781C159641895 @default.
• W4225302781 hasConceptScore W4225302781C2777645128 @default.

• next