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- W4225310568 abstract "In diabetes mellitus (DM) patients retinal complications were typically considered part of a vascular process. Recent research suggests that retinal degeneration in DM might also be caused by a neuropathy that could precede microvascular alterations. The present work reviews the currently available bibliography about neurodegeneration in patients with type 2 DM (DM2) without diabetic retinopathy (DR). In patients with non-severe, early DM2 without DR and good metabolic control visual function parameters show early abnormalities that precede clinical DR (in which we diagnose with a conventional ophthalmological examination). Using optical coherence tomography (OCT) technology, a reduction in macular and peripapillary thickness has been observed in different studies. Recent researches suggest that systemic complications (especially ischaemia) and a possible microvascular alteration eventually contributes to retinal neurodegeneration, which opens the door to new studies that include new techniques for evaluating the microvascularization of the retinal layers." @default.
- W4225310568 created "2022-05-05" @default.
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- W4225310568 date "2022-04-01" @default.
- W4225310568 modified "2023-09-30" @default.
- W4225310568 title "Retinal neurodegeneration in patients with type 2 diabetes mellitus without diabetic retinopathy" @default.
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- W4225310568 doi "https://doi.org/10.1016/j.oftale.2022.02.009" @default.
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