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• W4225375732 endingPage "444" @default.
• W4225375732 startingPage "429" @default.
• W4225375732 abstract "Abstract The COVID-19 pandemic continues to pose a serious global challenge, with the world engulfed in fighting second, third and fourth waves of the disease, which is reaching scary proportions in terms of cases and mortality in countries like India. Despite the urgent need of proven management protocols, there is still confusion about the best practices for treating COVID-19 with different pharmaceutical interventions. Antimicrobials are empirically used in COVID-19 patients. During the initial phase of this pandemic, hydroxychloroquine, ivermectin, azithromycin and doxycycline were widely suggested for possible prophylaxis or treatment for COVID-19 in outpatient as well as hospitalized settings. Various national and international guidelines recommended its use. However, cumulative evidence from subsequent clinical trials has revealed no significant clinical benefits in any setting, with the risk of adverse effects being high particularly in combination with azithromycin. Yet, there is continued use of antimicrobials particularly in outpatient settings which should be avoided because there is no justifiable rationale for doing so. Antimicrobial resistance (AMR) was one of the top problems for global public health before the coronavirus 2019 (COVID-19) pandemic began. AMR, which is already a difficult problem, must now be handled in the context of a changing healthcare sector." @default.
• W4225375732 created "2022-05-05" @default.
• W4225375732 creator A5001478992 @default.
• W4225375732 creator A5002472821 @default.
• W4225375732 date "2022-05-03" @default.
• W4225375732 modified "2023-09-27" @default.
• W4225375732 title "Antimicrobials in COVID-19: strategies for treating a COVID-19 pandemic" @default.
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• W4225375732 doi "https://doi.org/10.1515/jbcpp-2022-0061" @default.
• W4225375732 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35503307" @default.
• W4225375732 hasPublicationYear "2022" @default.
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