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- W4225426241 endingPage "119564" @default.
- W4225426241 startingPage "119564" @default.
- W4225426241 abstract "Human milk oligosaccharides (HMOs) are complex glycans that are the third largest solid component in human milk. It has attracted great interest in recent years due to their critical role in boosting infant health. These oligosaccharides play an important role in a variety of physiological processes, such as shaping the infant gut microbiome, preventing pathogenic infections and promoting the development of immune system. However, limited availability of HMOs hampered their use in food and medical areas. Moreover, most of the HMOs are unique to human milk and difficult to isolate. The strategies, chemical synthesis, whole-cell fermentation, and purification from human milk, have their advantages and come with their own challenges. In this review, we examined the remarkable progress that has been made in the enzymatic and chemoenzymatic synthesis of HMOs, and discussed the challenges and opportunities in large-scale synthesis of HMOs." @default.
- W4225426241 created "2022-05-05" @default.
- W4225426241 creator A5013698242 @default.
- W4225426241 creator A5050803462 @default.
- W4225426241 creator A5075141324 @default.
- W4225426241 creator A5081111762 @default.
- W4225426241 date "2022-09-01" @default.
- W4225426241 modified "2023-10-15" @default.
- W4225426241 title "Enzymatic and chemoenzymatic synthesis of human milk oligosaccharides and derivatives" @default.
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