Matches in SemOpenAlex for { <https://semopenalex.org/work/W4225503407> ?p ?o ?g. }
- W4225503407 endingPage "247" @default.
- W4225503407 startingPage "233" @default.
- W4225503407 abstract "Abstract Vitamin C (ascorbic acid) is a water-soluble vitamin with an array of biological functions. A number of proposed factors contribute to the vitamin’s plasma bioavailability and ability to exert optimal functionality. The aim of this review was to systematically assess plasma vitamin C levels post-surgery compared with pre-surgery/the magnitude and time frame of potential changes in concentration. We searched the PUBMED, SCOPUS, SciSearch and the Cochrane Library databases between 1970 and April 2020 for relevant research papers. Prospective studies, control groups and true placebo groups derived from controlled trials that reported means and standard deviations of plasma vitamin C concentrations pre- and postoperatively were included into the meta-analysis. Data were grouped into short-term (≤7 d) and long-term (>7 d) postoperative follow-up. Twenty-three of thirty-one studies involving 642 patients included in the systematic review were suitable for meta-analysis. Pooled data from the meta-analysis revealed a mean depletion of plasma vitamin C concentration of −17·99 µmol/l (39 % depletion) (CI −22·81, −13·17) (trial arms = 25, n 565, P < 0·001) during the first postoperative week and −18·80 µmol/l (21 % depletion) (CI −25·04, −12·56) (trial arms = 6, n 166, P < 0·001) 2–3 months postoperatively. Subgroup analyses revealed that these depletions occurred following different types of surgery; however, high heterogeneity was observed amongst trials assessing concentration change during the first postoperative week. Overall, our results warrant larger, long-term investigations of changes in postoperative plasma vitamin C concentrations and their potential effects on clinical symptomology." @default.
- W4225503407 created "2022-05-05" @default.
- W4225503407 creator A5018799933 @default.
- W4225503407 creator A5040675759 @default.
- W4225503407 creator A5054318696 @default.
- W4225503407 creator A5066769179 @default.
- W4225503407 creator A5068339243 @default.
- W4225503407 creator A5078958199 @default.
- W4225503407 date "2020-11-04" @default.
- W4225503407 modified "2023-10-17" @default.
- W4225503407 title "The effects of surgery on plasma/serum vitamin C concentrations: a systematic review and meta-analysis" @default.
- W4225503407 cites W1491755566 @default.
- W4225503407 cites W1767557134 @default.
- W4225503407 cites W1892541699 @default.
- W4225503407 cites W1944409733 @default.
- W4225503407 cites W1969982879 @default.
- W4225503407 cites W1973914781 @default.
- W4225503407 cites W1974286827 @default.
- W4225503407 cites W1976872554 @default.
- W4225503407 cites W1982187058 @default.
- W4225503407 cites W1983193908 @default.
- W4225503407 cites W1985829807 @default.
- W4225503407 cites W1989712972 @default.
- W4225503407 cites W1990395615 @default.
- W4225503407 cites W1995983924 @default.
- W4225503407 cites W2003184372 @default.
- W4225503407 cites W2006795534 @default.
- W4225503407 cites W2007194734 @default.
- W4225503407 cites W2013559465 @default.
- W4225503407 cites W2014391467 @default.
- W4225503407 cites W2019658801 @default.
- W4225503407 cites W2020143699 @default.
- W4225503407 cites W2024862672 @default.
- W4225503407 cites W2025722003 @default.
- W4225503407 cites W2028948274 @default.
- W4225503407 cites W2029538469 @default.
- W4225503407 cites W2032292945 @default.
- W4225503407 cites W2033242955 @default.
- W4225503407 cites W2038422402 @default.
- W4225503407 cites W2038742191 @default.
- W4225503407 cites W2046106090 @default.
- W4225503407 cites W2048255543 @default.
- W4225503407 cites W2048573347 @default.
- W4225503407 cites W2052639290 @default.
- W4225503407 cites W2056436725 @default.
- W4225503407 cites W2062284472 @default.
- W4225503407 cites W2066129630 @default.
- W4225503407 cites W2066857339 @default.
- W4225503407 cites W2067811178 @default.
- W4225503407 cites W2067812484 @default.
- W4225503407 cites W2071207565 @default.
- W4225503407 cites W2079212138 @default.
- W4225503407 cites W2079567241 @default.
- W4225503407 cites W2079698275 @default.
- W4225503407 cites W2093570404 @default.
- W4225503407 cites W2107128128 @default.
- W4225503407 cites W2125678006 @default.
- W4225503407 cites W2133647786 @default.
- W4225503407 cites W2142774757 @default.
- W4225503407 cites W2145140991 @default.
- W4225503407 cites W2146577725 @default.
- W4225503407 cites W2146644275 @default.
- W4225503407 cites W2152336364 @default.
- W4225503407 cites W2154546880 @default.
- W4225503407 cites W2157183439 @default.
- W4225503407 cites W2159245853 @default.
- W4225503407 cites W2159733957 @default.
- W4225503407 cites W2161975983 @default.
- W4225503407 cites W2162990612 @default.
- W4225503407 cites W2173612202 @default.
- W4225503407 cites W2185467805 @default.
- W4225503407 cites W2288447555 @default.
- W4225503407 cites W2327512031 @default.
- W4225503407 cites W2333388184 @default.
- W4225503407 cites W2470949765 @default.
- W4225503407 cites W2544532204 @default.
- W4225503407 cites W2550453242 @default.
- W4225503407 cites W2567362164 @default.
- W4225503407 cites W2573478684 @default.
- W4225503407 cites W2606879662 @default.
- W4225503407 cites W2619372624 @default.
- W4225503407 cites W2726829318 @default.
- W4225503407 cites W2746056021 @default.
- W4225503407 cites W2752339005 @default.
- W4225503407 cites W2766820812 @default.
- W4225503407 cites W2794422490 @default.
- W4225503407 cites W2795338498 @default.
- W4225503407 cites W2810376094 @default.
- W4225503407 cites W2810864124 @default.
- W4225503407 cites W2887489546 @default.
- W4225503407 cites W2888978102 @default.
- W4225503407 cites W2900468784 @default.
- W4225503407 cites W2912536857 @default.
- W4225503407 cites W2926048608 @default.
- W4225503407 cites W2971932427 @default.
- W4225503407 cites W2997288324 @default.
- W4225503407 cites W2997599418 @default.
- W4225503407 cites W2999085550 @default.