Matches in SemOpenAlex for { <https://semopenalex.org/work/W4225512229> ?p ?o ?g. }
- W4225512229 abstract "Abstract DNA methylation is a central epigenetic mark that has diverse roles in gene regulation, development, and maintenance of genome integrity. 5 methyl cytosine (5mC) can be interrogated at base resolution in single cells by using bisulfite sequencing (scWGBS). Several different scWGBS strategies have been described in recent years to study DNA methylation in single cells. However, there remain limitations with respect to cost-efficiency and yield. Herein, we present a new development in the field of scWGBS library preparation; single cell Splinted Ligation Adapter Tagging (scSPLAT). scSPLAT employs a pooling strategy to facilitate sample preparation at a higher scale and throughput than previously possible. We demonstrate the accuracy and robustness of the method by generating data from 225 single K562 cells and from 309 single liver nuclei and compare scSPLAT against other scWGBS methods." @default.
- W4225512229 created "2022-05-05" @default.
- W4225512229 creator A5019806116 @default.
- W4225512229 creator A5027395445 @default.
- W4225512229 creator A5040276109 @default.
- W4225512229 creator A5041059608 @default.
- W4225512229 creator A5065728135 @default.
- W4225512229 creator A5066763304 @default.
- W4225512229 creator A5088365661 @default.
- W4225512229 creator A5088850256 @default.
- W4225512229 date "2022-04-06" @default.
- W4225512229 modified "2023-09-25" @default.
- W4225512229 title "scSPLAT, a scalable plate-based protocol for single cell WGBS library preparation" @default.
- W4225512229 cites W1927990266 @default.
- W4225512229 cites W2006772779 @default.
- W4225512229 cites W2014677321 @default.
- W4225512229 cites W2065340354 @default.
- W4225512229 cites W2070339716 @default.
- W4225512229 cites W2120432300 @default.
- W4225512229 cites W2131374955 @default.
- W4225512229 cites W2139368808 @default.
- W4225512229 cites W2150936392 @default.
- W4225512229 cites W2259938310 @default.
- W4225512229 cites W2461038129 @default.
- W4225512229 cites W2529694725 @default.
- W4225512229 cites W2559478775 @default.
- W4225512229 cites W2744040456 @default.
- W4225512229 cites W2797310920 @default.
- W4225512229 cites W2885355806 @default.
- W4225512229 cites W2950909085 @default.
- W4225512229 cites W2951699355 @default.
- W4225512229 cites W3011701855 @default.
- W4225512229 cites W3042896257 @default.
- W4225512229 cites W3045759143 @default.
- W4225512229 cites W3089119159 @default.
- W4225512229 cites W3097109460 @default.
- W4225512229 cites W3104116520 @default.
- W4225512229 cites W3124346345 @default.
- W4225512229 cites W3156793915 @default.
- W4225512229 cites W3184729641 @default.
- W4225512229 cites W3203959602 @default.
- W4225512229 cites W4210848872 @default.
- W4225512229 cites W4233234547 @default.
- W4225512229 doi "https://doi.org/10.1038/s41598-022-09798-2" @default.
- W4225512229 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35388090" @default.
- W4225512229 hasPublicationYear "2022" @default.
- W4225512229 type Work @default.
- W4225512229 citedByCount "3" @default.
- W4225512229 countsByYear W42255122292022 @default.
- W4225512229 countsByYear W42255122292023 @default.
- W4225512229 crossrefType "journal-article" @default.
- W4225512229 hasAuthorship W4225512229A5019806116 @default.
- W4225512229 hasAuthorship W4225512229A5027395445 @default.
- W4225512229 hasAuthorship W4225512229A5040276109 @default.
- W4225512229 hasAuthorship W4225512229A5041059608 @default.
- W4225512229 hasAuthorship W4225512229A5065728135 @default.
- W4225512229 hasAuthorship W4225512229A5066763304 @default.
- W4225512229 hasAuthorship W4225512229A5088365661 @default.
- W4225512229 hasAuthorship W4225512229A5088850256 @default.
- W4225512229 hasBestOaLocation W42255122291 @default.
- W4225512229 hasConcept C104317684 @default.
- W4225512229 hasConcept C150194340 @default.
- W4225512229 hasConcept C153911025 @default.
- W4225512229 hasConcept C177284502 @default.
- W4225512229 hasConcept C189235521 @default.
- W4225512229 hasConcept C190727270 @default.
- W4225512229 hasConcept C41008148 @default.
- W4225512229 hasConcept C41091548 @default.
- W4225512229 hasConcept C54355233 @default.
- W4225512229 hasConcept C70721500 @default.
- W4225512229 hasConcept C86803240 @default.
- W4225512229 hasConcept C9390403 @default.
- W4225512229 hasConceptScore W4225512229C104317684 @default.
- W4225512229 hasConceptScore W4225512229C150194340 @default.
- W4225512229 hasConceptScore W4225512229C153911025 @default.
- W4225512229 hasConceptScore W4225512229C177284502 @default.
- W4225512229 hasConceptScore W4225512229C189235521 @default.
- W4225512229 hasConceptScore W4225512229C190727270 @default.
- W4225512229 hasConceptScore W4225512229C41008148 @default.
- W4225512229 hasConceptScore W4225512229C41091548 @default.
- W4225512229 hasConceptScore W4225512229C54355233 @default.
- W4225512229 hasConceptScore W4225512229C70721500 @default.
- W4225512229 hasConceptScore W4225512229C86803240 @default.
- W4225512229 hasConceptScore W4225512229C9390403 @default.
- W4225512229 hasFunder F4320316588 @default.
- W4225512229 hasFunder F4320322581 @default.
- W4225512229 hasFunder F4320324119 @default.
- W4225512229 hasIssue "1" @default.
- W4225512229 hasLocation W42255122291 @default.
- W4225512229 hasLocation W42255122292 @default.
- W4225512229 hasLocation W42255122293 @default.
- W4225512229 hasLocation W42255122294 @default.
- W4225512229 hasLocation W42255122295 @default.
- W4225512229 hasOpenAccess W4225512229 @default.
- W4225512229 hasPrimaryLocation W42255122291 @default.
- W4225512229 hasRelatedWork W172747452 @default.
- W4225512229 hasRelatedWork W2049208989 @default.
- W4225512229 hasRelatedWork W2070339716 @default.
- W4225512229 hasRelatedWork W295630533 @default.
- W4225512229 hasRelatedWork W3004424038 @default.