FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4225515604> ?p ?o ?g. }

• W4225515604 abstract "Abstract The advent of BTK inhibitors has changed the treatment of patients with chronic lymphocytic leukemia (CLL) and mantle cell lymphoma (MCL). The first-in-class BTK inhibitor ibrutinib has shown remarkable therapeutic effects and manageable toxicities in multiple clinical trials. The second-generation BTK inhibitors, including acalabrutinib and zanubrutinib, also show remarkable efficacies. However, using BTK inhibitors as monotherapies requires continuous treatment. Resistance to BTK inhibitors and severe side effects unavoidably occur during BTK inhibitor monotherapy, frequently resulting in treatment failure. The addition of the BCL2 inhibitor venetoclax to BTK inhibitor may improve the therapeutic effects and result in deeper responses, providing a potential fixed-duration treatment, especially for patients with CLL. In this review, by focusing on CLL and MCL, we discussed the rationale for the combinational use and summarized the current data on the combinations of BTK inhibitors and venetoclax in patients with CLL and MCL." @default.
• W4225515604 created "2022-05-05" @default.
• W4225515604 creator A5004949255 @default.
• W4225515604 creator A5017947172 @default.
• W4225515604 creator A5018556256 @default.
• W4225515604 creator A5040795581 @default.
• W4225515604 date "2022-04-04" @default.
• W4225515604 modified "2023-10-18" @default.
• W4225515604 title "Combining BTK inhibitors with BCL2 inhibitors for treating chronic lymphocytic leukemia and mantle cell lymphoma" @default.
• W4225515604 cites W1829587101 @default.
• W4225515604 cites W2030263904 @default.
• W4225515604 cites W2108206643 @default.
• W4225515604 cites W2120319857 @default.
• W4225515604 cites W2131823788 @default.
• W4225515604 cites W2153923291 @default.
• W4225515604 cites W2154066874 @default.
• W4225515604 cites W2172718055 @default.
• W4225515604 cites W2192121806 @default.
• W4225515604 cites W2233614027 @default.
• W4225515604 cites W2296618733 @default.
• W4225515604 cites W2345930858 @default.
• W4225515604 cites W2512656347 @default.
• W4225515604 cites W2516544744 @default.
• W4225515604 cites W2568089859 @default.
• W4225515604 cites W2580821712 @default.
• W4225515604 cites W2582696216 @default.
• W4225515604 cites W2589238872 @default.
• W4225515604 cites W2611867488 @default.
• W4225515604 cites W2737907117 @default.
• W4225515604 cites W2739393823 @default.
• W4225515604 cites W2773047201 @default.
• W4225515604 cites W2795301499 @default.
• W4225515604 cites W2886452066 @default.
• W4225515604 cites W2891539827 @default.
• W4225515604 cites W2902484351 @default.
• W4225515604 cites W2902706178 @default.
• W4225515604 cites W2904933400 @default.
• W4225515604 cites W2941780980 @default.
• W4225515604 cites W2946307215 @default.
• W4225515604 cites W2962038803 @default.
• W4225515604 cites W2966190920 @default.
• W4225515604 cites W2973195462 @default.
• W4225515604 cites W2980937306 @default.
• W4225515604 cites W2989626047 @default.
• W4225515604 cites W2989894850 @default.
• W4225515604 cites W2999980976 @default.
• W4225515604 cites W3016538158 @default.
• W4225515604 cites W3039488989 @default.
• W4225515604 cites W3088078660 @default.
• W4225515604 cites W3091792544 @default.
• W4225515604 cites W3092038997 @default.
• W4225515604 cites W3094928012 @default.
• W4225515604 cites W3094960558 @default.
• W4225515604 cites W3095558229 @default.
• W4225515604 cites W3096191746 @default.
• W4225515604 cites W3097014789 @default.
• W4225515604 cites W3097263470 @default.
• W4225515604 cites W3097432526 @default.
• W4225515604 cites W3105196097 @default.
• W4225515604 cites W3130132423 @default.
• W4225515604 cites W3132537256 @default.
• W4225515604 cites W3135275383 @default.
• W4225515604 cites W3136990383 @default.
• W4225515604 cites W3139147523 @default.
• W4225515604 cites W3158332554 @default.
• W4225515604 cites W3169739858 @default.
• W4225515604 cites W3200592707 @default.
• W4225515604 cites W3203683811 @default.
• W4225515604 cites W3208067790 @default.
• W4225515604 cites W3208680410 @default.
• W4225515604 cites W3209564082 @default.
• W4225515604 cites W3210638874 @default.
• W4225515604 cites W3211809601 @default.
• W4225515604 cites W3211846518 @default.
• W4225515604 cites W3212153629 @default.
• W4225515604 cites W3212206140 @default.
• W4225515604 cites W4200440187 @default.
• W4225515604 cites W4210458420 @default.
• W4225515604 doi "https://doi.org/10.1186/s40364-022-00357-5" @default.
• W4225515604 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35379357" @default.
• W4225515604 hasPublicationYear "2022" @default.
• W4225515604 type Work @default.
• W4225515604 citedByCount "8" @default.
• W4225515604 countsByYear W42255156042022 @default.
• W4225515604 countsByYear W42255156042023 @default.
• W4225515604 crossrefType "journal-article" @default.
• W4225515604 hasAuthorship W4225515604A5004949255 @default.
• W4225515604 hasAuthorship W4225515604A5017947172 @default.
• W4225515604 hasAuthorship W4225515604A5018556256 @default.
• W4225515604 hasAuthorship W4225515604A5040795581 @default.
• W4225515604 hasBestOaLocation W42255156041 @default.
• W4225515604 hasConcept C126322002 @default.
• W4225515604 hasConcept C143998085 @default.
• W4225515604 hasConcept C170493617 @default.
• W4225515604 hasConcept C203014093 @default.
• W4225515604 hasConcept C2777525834 @default.
• W4225515604 hasConcept C2777938653 @default.
• W4225515604 hasConcept C2778461978 @default.
• W4225515604 hasConcept C2779338263 @default.
• W4225515604 hasConcept C2779675984 @default.

• next