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- W4225519502 abstract "Cassava, a food security crop in Africa, is grown throughout the tropics and subtropics. Although cassava can provide high productivity in suboptimal conditions, the yield in Africa is substantially lower than in other geographies. The yield gap is attributable to many challenges faced by cassava in Africa, including susceptibility to diseases and poor soil conditions. In this study, we carried out 3'RNA sequencing on 150 accessions from the National Crops Resources Research Institute, Uganda for 5 tissue types, providing population-based transcriptomics resources to the research community in a web-based queryable cassava expression atlas. Differential expression and weighted gene co-expression network analysis were performed to detect 8820 significantly differentially expressed genes (DEGs), revealing similarity in expression patterns between tissue types and the clustering of detected DEGs into 18 gene modules. As a confirmation of data quality, differential expression and pathway analysis targeting cassava mosaic disease (CMD) identified 27 genes observed in the plant-pathogen interaction pathway, several previously identified CMD resistance genes, and two peroxidase family proteins different from the CMD2 gene. Present research work represents a novel resource towards understanding complex traits at expression and molecular levels for the development of resistant and high-yielding cassava varieties, as exemplified with CMD." @default.
- W4225519502 created "2022-05-05" @default.
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- W4225519502 date "2021-12-07" @default.
- W4225519502 modified "2023-09-26" @default.
- W4225519502 title "A population based expression atlas provides insights into disease resistance and other physiological traits in cassava (Manihot esculenta Crantz)" @default.
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- W4225519502 doi "https://doi.org/10.1038/s41598-021-02794-y" @default.
- W4225519502 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34876620" @default.
- W4225519502 hasPublicationYear "2021" @default.
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