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- W4225524069 abstract "Abstract Objective To describe prescription prevalence of oral bladder pain medications among women with interstitial cystitis/bladder pain syndrome (IC/BPS) and to compare with current treatment guidelines. Methods We sampled female patients with an ICD‐9/10 diagnosis of IC/BPS (595.1/N30.10) by querying active users of the Veterans Health Administration. Medical records were reviewed to determine whether patients met IC/BPS diagnostic criteria. A cohort of women with other pelvic pain disorders was identified. Prescription prevalence of typical non‐narcotic oral bladder pain medications was compared between the two groups and healthy controls. Prescription prevalence was also compared before and after the diagnosis of IC/BPS was made using Poisson regression. Results There were 641 women who met criteria for IC/BPS and 197 women with “Other pelvic pain” disorders. Women with IC/BPS were prescribed a pain medication more often than those with “Other pelvic pain” (77% vs. 59%, p < 0.0001). Of the women with IC/BPS, 44% tried three or more pain medications. Of women with a diagnosis of IC/BPS, only 67% were prescribed an American Urological Association‐recommended medication. Prescription prevalence increased after diagnosis for both pentosan polysulfate (10%–29%, p < 0.0001) and hydroxyzine (17%–40%, p < 0.0001), but not for amitriptyline or cimetidine. Amitriptyline was prescribed to 223 women with IC/BPS, only 125 of which (56%) had a documented history of depression. Conclusions Many women with IC/BPS required multiple bladder prescriptions, highlighting the difficulty in finding an effective treatment for IC/BPS. Pentosan polysulfate and hydroxyzine were preferred IC/BPS medications. Our next step will be to analyze treatment patterns in those patients who did not receive medications." @default.
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- W4225524069 date "2022-04-07" @default.
- W4225524069 modified "2023-10-16" @default.
- W4225524069 title "Do medication prescription patterns follow guidelines in a cohort of women with interstitial cystitis/bladder pain syndrome?" @default.
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- W4225524069 doi "https://doi.org/10.1002/nau.24923" @default.
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