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• W4225526223 abstract "We described a novel HIV autologous isolation method based in coculturing macrophages and CD4+T-cell-enriched fractions from peripheral blood collected from antiretroviral-treated (ART) HIV patients. This method allows the isolation of high viral titers of autologous viruses, over 1010HIV RNA copies/ml, and reduces the time required to produce necessary amounts for virus for use as antigens presented by monocyte-derived myeloid cells in HIV therapeutic vaccine approaches. By applying these high titer and autologous virus produced in the patient-derived cells, we intended to elicit a boost of the immunological system response in HIV therapeutic vaccines in clinical trials." @default.
• W4225526223 created "2022-05-05" @default.
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• W4225526223 date "2022-04-07" @default.
• W4225526223 modified "2023-10-18" @default.
• W4225526223 title "Highly Efficient Autologous HIV-1 Isolation by Coculturing Macrophage With Enriched CD4+ T Cells From HIV-1 Patients" @default.
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• W4225526223 doi "https://doi.org/10.3389/fviro.2022.869431" @default.
• W4225526223 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35967461" @default.
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