Matches in SemOpenAlex for { <https://semopenalex.org/work/W4225556912> ?p ?o ?g. }
- W4225556912 endingPage "80" @default.
- W4225556912 startingPage "72" @default.
- W4225556912 abstract "Long-term efficacy and mechanisms of action of deep brain stimulation (DBS) for treatment-resistant depression (TRD) are under investigation.To compare long-term outcomes with active electrode's coordinates and its electrical parameters in patients with TRD treated with DBS in the subgenual cingulate gyrus (SCG-DBS).Seventeen patients with TRD underwent SCG-DBS. Demographic and baseline characteristics were recorded. The 17-item Hamilton Depression Rating Scale was used to measure the response to the therapy. The anterior commissure-posterior commissure coordinates of the active contacts and the total electrical energy delivered were calculated and correlated with clinical outcomes. Patient-specific tractographic analysis was performed to identify the modulated pathways in responders.Twelve women (70.6%) and 5 men (29.4%) with a median age of 48 yr (34-70 years) were included. Along the 5-year follow-up, 3 main clinical trajectories were observed according to symptom's improvement: great responders (≥80%), medium responders (≥50%-79%), and poor responders (<50%). Active contacts' coordinates and total electrical energy delivered showed no correlation with clinical outcomes. Brodmann area 10 medial was the most frequently stimulated area and the forceps minor, the most frequently modulated tract.SCG-DBS for TRD is clearly effective in some patients. Active contacts' coordinates were highly variable within the region and, like electrical parameters, did not seem to correlate with clinical outcomes. In the current series, Brodmann area 10 medial and the forceps minor were the most frequently targeted area and modulated pathway, respectively." @default.
- W4225556912 created "2022-05-05" @default.
- W4225556912 creator A5004055966 @default.
- W4225556912 creator A5024509508 @default.
- W4225556912 creator A5036634737 @default.
- W4225556912 creator A5049716977 @default.
- W4225556912 creator A5051773877 @default.
- W4225556912 creator A5060349505 @default.
- W4225556912 creator A5066688172 @default.
- W4225556912 creator A5080949478 @default.
- W4225556912 date "2021-11-29" @default.
- W4225556912 modified "2023-10-14" @default.
- W4225556912 title "Long-Term Results of Deep Brain Stimulation for Treatment-Resistant Depression: Outcome Analysis and Correlation With Lead Position and Electrical Parameters" @default.
- W4225556912 cites W1869776851 @default.
- W4225556912 cites W1965965542 @default.
- W4225556912 cites W1977723029 @default.
- W4225556912 cites W1989615119 @default.
- W4225556912 cites W2008635511 @default.
- W4225556912 cites W2042982960 @default.
- W4225556912 cites W2043220571 @default.
- W4225556912 cites W2058805315 @default.
- W4225556912 cites W2059704767 @default.
- W4225556912 cites W2072296702 @default.
- W4225556912 cites W2081443882 @default.
- W4225556912 cites W2099527308 @default.
- W4225556912 cites W2100802590 @default.
- W4225556912 cites W2122595758 @default.
- W4225556912 cites W2128682567 @default.
- W4225556912 cites W2132324173 @default.
- W4225556912 cites W2132969335 @default.
- W4225556912 cites W2140182471 @default.
- W4225556912 cites W2151821422 @default.
- W4225556912 cites W2169815799 @default.
- W4225556912 cites W2334792938 @default.
- W4225556912 cites W2342584978 @default.
- W4225556912 cites W2606960287 @default.
- W4225556912 cites W2761803381 @default.
- W4225556912 cites W2763173694 @default.
- W4225556912 cites W2777987555 @default.
- W4225556912 cites W2800798196 @default.
- W4225556912 cites W2809637028 @default.
- W4225556912 cites W2906471327 @default.
- W4225556912 cites W2970623573 @default.
- W4225556912 cites W2978891835 @default.
- W4225556912 cites W2996585831 @default.
- W4225556912 cites W3037705498 @default.
- W4225556912 cites W3135590296 @default.
- W4225556912 cites W57359236 @default.
- W4225556912 doi "https://doi.org/10.1227/neu.0000000000001739" @default.
- W4225556912 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34982873" @default.
- W4225556912 hasPublicationYear "2021" @default.
- W4225556912 type Work @default.
- W4225556912 citedByCount "3" @default.
- W4225556912 countsByYear W42255569122022 @default.
- W4225556912 countsByYear W42255569122023 @default.
- W4225556912 crossrefType "journal-article" @default.
- W4225556912 hasAuthorship W4225556912A5004055966 @default.
- W4225556912 hasAuthorship W4225556912A5024509508 @default.
- W4225556912 hasAuthorship W4225556912A5036634737 @default.
- W4225556912 hasAuthorship W4225556912A5049716977 @default.
- W4225556912 hasAuthorship W4225556912A5051773877 @default.
- W4225556912 hasAuthorship W4225556912A5060349505 @default.
- W4225556912 hasAuthorship W4225556912A5066688172 @default.
- W4225556912 hasAuthorship W4225556912A5080949478 @default.
- W4225556912 hasConcept C118552586 @default.
- W4225556912 hasConcept C126322002 @default.
- W4225556912 hasConcept C139719470 @default.
- W4225556912 hasConcept C141071460 @default.
- W4225556912 hasConcept C162324750 @default.
- W4225556912 hasConcept C2776867660 @default.
- W4225556912 hasConcept C2778092261 @default.
- W4225556912 hasConcept C2778542668 @default.
- W4225556912 hasConcept C2779134260 @default.
- W4225556912 hasConcept C2779734285 @default.
- W4225556912 hasConcept C2780723820 @default.
- W4225556912 hasConcept C71924100 @default.
- W4225556912 hasConcept C99508421 @default.
- W4225556912 hasConceptScore W4225556912C118552586 @default.
- W4225556912 hasConceptScore W4225556912C126322002 @default.
- W4225556912 hasConceptScore W4225556912C139719470 @default.
- W4225556912 hasConceptScore W4225556912C141071460 @default.
- W4225556912 hasConceptScore W4225556912C162324750 @default.
- W4225556912 hasConceptScore W4225556912C2776867660 @default.
- W4225556912 hasConceptScore W4225556912C2778092261 @default.
- W4225556912 hasConceptScore W4225556912C2778542668 @default.
- W4225556912 hasConceptScore W4225556912C2779134260 @default.
- W4225556912 hasConceptScore W4225556912C2779734285 @default.
- W4225556912 hasConceptScore W4225556912C2780723820 @default.
- W4225556912 hasConceptScore W4225556912C71924100 @default.
- W4225556912 hasConceptScore W4225556912C99508421 @default.
- W4225556912 hasIssue "1" @default.
- W4225556912 hasLocation W42255569121 @default.
- W4225556912 hasLocation W42255569122 @default.
- W4225556912 hasOpenAccess W4225556912 @default.
- W4225556912 hasPrimaryLocation W42255569121 @default.
- W4225556912 hasRelatedWork W178081488 @default.
- W4225556912 hasRelatedWork W2106215760 @default.
- W4225556912 hasRelatedWork W2114827170 @default.