Matches in SemOpenAlex for { <https://semopenalex.org/work/W4225565502> ?p ?o ?g. }
Showing items 1 to 59 of
59
with 100 items per page.
- W4225565502 abstract "Comparison of clinical and pathological features of secondary IgA nephropathy of ankylosing spondylitis (SIgAN-AS) and primary IgA nephropathy (PIgAN).Clinical characteristics and pathological data of patients diagnosed with IgAN by renal biopsy were collected in our hospital from January 2008 to October 2018. Patients with SIgAN-AS and PIgAN were recruited at a ratio of 1 : 5. Fifteen patients with SIgAN-AS and 75 patients with PIgAN were enrolled in this retrospective study.There were 15 cases in the SIgAN-AS group, including 13 males and 2 females. The cohort of 75 patients with PIgAN included 37 males and 38 females. There were significantly more males in the SIgAN-AS group 13/15 (86.67%) vs 37/75 (49.30%), p < 0.05. Compared with PIgAN patients, SIgAN-AS patients had higher incidences of hematuria (12/15 (80.00%) vs. 37/75 (49.33%), p < 0.05), lower levels of 24-hour urinary protein (0.85 ± 0.68 vs. 1.57 ± 1.54 g, p < 0.05), but higher levels of estimated glomerular filtration rate (eGFR) (CKD-EPI formula; 112.56 ± 24.53 vs. 88.23 ± 29.39, p < 0.05), albumin (44.67 ± 3.48 vs. 41.09 ± 7.07 g/L, p < 0.05), erythrocyte sedimentation rate (ESR) (43.20 ± 33.94 vs. 18.79 ± 16.26 mm/h, p < 0.001), and C-reactive protein (CRP) (21.19 ± 30.61 vs. 2.11 ± 4.58 mg/L, p < 0.001). From the perspective of renal pathology of PIgAN, patients with SIgAN-AS had a lower incidence of renal tubular atrophy/interstitial fibrosis of nephropathy (p < 0.05). Immunohistostaining analysis showed a higher incidence of dominant deposits of single IgA in the mesangial cell area (p < 0.05).SIgAN-AS was more commonly observed in males and displayed a milder progression than those PIgAN. The majority of SIgAN-AS patients can be improved by early intervention." @default.
- W4225565502 created "2022-05-05" @default.
- W4225565502 creator A5023925858 @default.
- W4225565502 creator A5028646197 @default.
- W4225565502 creator A5045970154 @default.
- W4225565502 date "2022-01-24" @default.
- W4225565502 modified "2023-09-25" @default.
- W4225565502 title "Comparison of clinical and pathological features of secondary IgA nephropathy of ankylosing spondylitis and primary IgA nephropathy" @default.
- W4225565502 doi "https://doi.org/10.5414/cn110645" @default.
- W4225565502 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35072620" @default.
- W4225565502 hasPublicationYear "2022" @default.
- W4225565502 type Work @default.
- W4225565502 citedByCount "1" @default.
- W4225565502 countsByYear W42255655022023 @default.
- W4225565502 crossrefType "journal-article" @default.
- W4225565502 hasAuthorship W4225565502A5023925858 @default.
- W4225565502 hasAuthorship W4225565502A5028646197 @default.
- W4225565502 hasAuthorship W4225565502A5045970154 @default.
- W4225565502 hasConcept C126322002 @default.
- W4225565502 hasConcept C134018914 @default.
- W4225565502 hasConcept C159641895 @default.
- W4225565502 hasConcept C207886595 @default.
- W4225565502 hasConcept C2777402515 @default.
- W4225565502 hasConcept C2778143017 @default.
- W4225565502 hasConcept C2779650986 @default.
- W4225565502 hasConcept C2781087799 @default.
- W4225565502 hasConcept C2781184683 @default.
- W4225565502 hasConcept C555293320 @default.
- W4225565502 hasConcept C71924100 @default.
- W4225565502 hasConcept C90924648 @default.
- W4225565502 hasConceptScore W4225565502C126322002 @default.
- W4225565502 hasConceptScore W4225565502C134018914 @default.
- W4225565502 hasConceptScore W4225565502C159641895 @default.
- W4225565502 hasConceptScore W4225565502C207886595 @default.
- W4225565502 hasConceptScore W4225565502C2777402515 @default.
- W4225565502 hasConceptScore W4225565502C2778143017 @default.
- W4225565502 hasConceptScore W4225565502C2779650986 @default.
- W4225565502 hasConceptScore W4225565502C2781087799 @default.
- W4225565502 hasConceptScore W4225565502C2781184683 @default.
- W4225565502 hasConceptScore W4225565502C555293320 @default.
- W4225565502 hasConceptScore W4225565502C71924100 @default.
- W4225565502 hasConceptScore W4225565502C90924648 @default.
- W4225565502 hasLocation W42255655021 @default.
- W4225565502 hasLocation W42255655022 @default.
- W4225565502 hasOpenAccess W4225565502 @default.
- W4225565502 hasPrimaryLocation W42255655021 @default.
- W4225565502 hasRelatedWork W2112058 @default.
- W4225565502 hasRelatedWork W2133091 @default.
- W4225565502 hasRelatedWork W21963069 @default.
- W4225565502 hasRelatedWork W220526 @default.
- W4225565502 hasRelatedWork W2697908 @default.
- W4225565502 hasRelatedWork W2842080 @default.
- W4225565502 hasRelatedWork W28483839 @default.
- W4225565502 hasRelatedWork W3246496 @default.
- W4225565502 hasRelatedWork W3317952 @default.
- W4225565502 hasRelatedWork W5026568 @default.
- W4225565502 isParatext "false" @default.
- W4225565502 isRetracted "false" @default.
- W4225565502 workType "article" @default.