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- W4225565558 abstract "Substance use disorders (SUDs) are heterogeneous and complex, making the development of translationally predictive rodent and nonhuman primate models to uncover their neurobehavioral underpinnings difficult. Neuroscience-focused outcomes have become highly prevalent, and with this, the notion that SUDs are disorders of the brain embraced as a dominant theoretical orientation to understand SUD etiology and treatment. These efforts, however, have led to few efficacious pharmacotherapies, and in some cases (as with cocaine or methamphetamine), no pharmacotherapies have translated from preclinical models for clinical use. In this theoretical commentary, we first describe the development of animal models of substance use behaviors from a historical perspective. We then define and discuss three logical fallacies including 1) circular explanation, 2) affirming the consequent, and 3) reification that can apply to developed models. We then provide three case examples in which conceptual or logical issues exist in common methods (i.e., behavioral economic demand, escalation, and reinstatement). Alternative strategies to refocus behavioral models are suggested for the field to better bridge the translational divide between animal models, the clinical condition of SUDs, and current and future regulatory pathways for intervention development." @default.
- W4225565558 created "2022-05-05" @default.
- W4225565558 creator A5023437507 @default.
- W4225565558 creator A5027917357 @default.
- W4225565558 creator A5071583939 @default.
- W4225565558 creator A5086703037 @default.
- W4225565558 date "2022-04-01" @default.
- W4225565558 modified "2023-10-14" @default.
- W4225565558 title "Logical fallacies and misinterpretations that hinder progress in translational addiction neuroscience" @default.
- W4225565558 cites W1044539853 @default.
- W4225565558 cites W1480740183 @default.
- W4225565558 cites W1513242235 @default.
- W4225565558 cites W1549471251 @default.
- W4225565558 cites W1555298184 @default.
- W4225565558 cites W1567339226 @default.
- W4225565558 cites W1771206806 @default.
- W4225565558 cites W1951949051 @default.
- W4225565558 cites W1958401950 @default.
- W4225565558 cites W1963514083 @default.
- W4225565558 cites W1965927079 @default.
- W4225565558 cites W1974215173 @default.
- W4225565558 cites W1978108699 @default.
- W4225565558 cites W1978686840 @default.
- W4225565558 cites W1979336889 @default.
- W4225565558 cites W1984708283 @default.
- W4225565558 cites W1989416066 @default.
- W4225565558 cites W1992249631 @default.
- W4225565558 cites W1993788684 @default.
- W4225565558 cites W1996364982 @default.
- W4225565558 cites W1999562402 @default.
- W4225565558 cites W2000825098 @default.
- W4225565558 cites W2002630314 @default.
- W4225565558 cites W2004866865 @default.
- W4225565558 cites W2007335607 @default.
- W4225565558 cites W2007816528 @default.
- W4225565558 cites W2008441751 @default.
- W4225565558 cites W2010890416 @default.
- W4225565558 cites W2013762461 @default.
- W4225565558 cites W2015420762 @default.
- W4225565558 cites W2015559939 @default.
- W4225565558 cites W2017042499 @default.
- W4225565558 cites W2020320083 @default.
- W4225565558 cites W2022677793 @default.
- W4225565558 cites W2022992863 @default.
- W4225565558 cites W2029087690 @default.
- W4225565558 cites W2029991885 @default.
- W4225565558 cites W2030310872 @default.
- W4225565558 cites W2031684877 @default.
- W4225565558 cites W2037639590 @default.
- W4225565558 cites W2037826673 @default.
- W4225565558 cites W2040903782 @default.
- W4225565558 cites W2041139441 @default.
- W4225565558 cites W2041450400 @default.
- W4225565558 cites W2045267424 @default.
- W4225565558 cites W2047831967 @default.
- W4225565558 cites W2051932502 @default.
- W4225565558 cites W2052814807 @default.
- W4225565558 cites W2053414348 @default.
- W4225565558 cites W2054749214 @default.
- W4225565558 cites W2054934812 @default.
- W4225565558 cites W2055610170 @default.
- W4225565558 cites W2057119584 @default.
- W4225565558 cites W2058726521 @default.
- W4225565558 cites W2059057223 @default.
- W4225565558 cites W2060324739 @default.
- W4225565558 cites W2060475215 @default.
- W4225565558 cites W2063753583 @default.
- W4225565558 cites W2064986703 @default.
- W4225565558 cites W2077041350 @default.
- W4225565558 cites W2079376601 @default.
- W4225565558 cites W2081834159 @default.
- W4225565558 cites W2083570864 @default.
- W4225565558 cites W2086313373 @default.
- W4225565558 cites W2087309661 @default.
- W4225565558 cites W2087657646 @default.
- W4225565558 cites W2090078976 @default.
- W4225565558 cites W2105024315 @default.
- W4225565558 cites W2105590889 @default.
- W4225565558 cites W2112323466 @default.
- W4225565558 cites W2114661800 @default.
- W4225565558 cites W2116939069 @default.
- W4225565558 cites W2117064082 @default.
- W4225565558 cites W2118826874 @default.
- W4225565558 cites W2121487646 @default.
- W4225565558 cites W2123766280 @default.
- W4225565558 cites W2125364966 @default.
- W4225565558 cites W2125695034 @default.
- W4225565558 cites W2127186356 @default.
- W4225565558 cites W2128423095 @default.
- W4225565558 cites W2129372385 @default.
- W4225565558 cites W2132099678 @default.
- W4225565558 cites W2132200881 @default.
- W4225565558 cites W2144137995 @default.
- W4225565558 cites W2145146057 @default.
- W4225565558 cites W2147773916 @default.
- W4225565558 cites W2151433332 @default.
- W4225565558 cites W2152023371 @default.
- W4225565558 cites W2152455734 @default.